HUP9902890A2 - Substituted pyrimidine derivatives and their pharmaceutical use - Google Patents
Substituted pyrimidine derivatives and their pharmaceutical useInfo
- Publication number
- HUP9902890A2 HUP9902890A2 HU9902890A HUP9902890A HUP9902890A2 HU P9902890 A2 HUP9902890 A2 HU P9902890A2 HU 9902890 A HU9902890 A HU 9902890A HU P9902890 A HUP9902890 A HU P9902890A HU P9902890 A2 HUP9902890 A2 HU P9902890A2
- Authority
- HU
- Hungary
- Prior art keywords
- alkyl
- pyrimidine derivatives
- halo
- alkenyl
- alkoxy
- Prior art date
Links
- 229940083082 pyrimidine derivative acting on arteriolar smooth muscle Drugs 0.000 title abstract 2
- 150000003230 pyrimidines Chemical class 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- 125000003342 alkenyl group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000001475 halogen functional group Chemical group 0.000 abstract 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 3
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 2
- 125000003282 alkyl amino group Chemical group 0.000 abstract 2
- 125000000304 alkynyl group Chemical group 0.000 abstract 2
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 2
- 125000005236 alkanoylamino group Chemical group 0.000 abstract 1
- 125000005115 alkyl carbamoyl group Chemical group 0.000 abstract 1
- 125000004644 alkyl sulfinyl group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000005530 alkylenedioxy group Chemical group 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000003831 tetrazolyl group Chemical group 0.000 abstract 1
Abstract
Substituted pyrimidine derivatives of formula (I) and their salts are new. T1 = N or CR; R = H, 1-4C alkyl, 2-4C alkenyl or 2-4C alkynyl; R1 = H, amino, halo, CN, 1-6C alkyl, 1-6C alkylamino, 2-6C dialkylamino or 1-6C alkoxy; m = 1-2; T2 = CH or N; T3 = N or CR; provided that when T2 = CH then T3 is not CR and when T1 = CR then T3 is not CR; a, b = 2-3; c, d = 1-2; the heterocycles containing T1 and T2 are optionally further substituted by 1-6C alkyl, 1-6C alkoxy, phenyl-1-4C alkyl, halo and/or 2-7C alkoxycarbonyl; X = O, CO, S, SO, SO2 or CH2; Q = Ph, naphthyl, phenyl-2-6C alkenyl or a 5-6 membered monocyclic heteroaryl containing 1-3 or N, O and/or S (optionally substituted by halo, OH, amino, NO2, CN, COOH, carbamoyl, 1-6C alkyl, 2-6C alkenyl, 2-6C alkynyl, 1-6C alkoxy, 3-6C cycloalkyl, 3-6C cycloalkyl-1-4C alkyl, 1-4C alkylenedioxy, 1-6C alkylamino, di-(1-6Calkyl) amino, N-1-6C alkylcarbamoyl, di (N-1-6C alkyl)carbamoyl, 1-6C alkanoylamino, 2-7C alkoxycarbonyl, 1-6C alkylthio, 1-6C alkylsulphinyl, 1-6C alkylsulphonyl, 1-6C haloalkyl, 1-6C alkanoyl or tetrazolyl).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9902890A HUP9902890A2 (en) | 1997-07-25 | 1997-07-25 | Substituted pyrimidine derivatives and their pharmaceutical use |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9902890A HUP9902890A2 (en) | 1997-07-25 | 1997-07-25 | Substituted pyrimidine derivatives and their pharmaceutical use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUP9902890A2 true HUP9902890A2 (en) | 1999-12-28 |
Family
ID=89999130
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9902890A HUP9902890A2 (en) | 1997-07-25 | 1997-07-25 | Substituted pyrimidine derivatives and their pharmaceutical use |
Country Status (1)
| Country | Link |
|---|---|
| HU (1) | HUP9902890A2 (en) |
-
1997
- 1997-07-25 HU HU9902890A patent/HUP9902890A2/en unknown
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