HUP9902563A2 - Piperidine derivatives, intermediates, preparation and use thereof - Google Patents
Piperidine derivatives, intermediates, preparation and use thereofInfo
- Publication number
- HUP9902563A2 HUP9902563A2 HU9902563A HUP9902563A HUP9902563A2 HU P9902563 A2 HUP9902563 A2 HU P9902563A2 HU 9902563 A HU9902563 A HU 9902563A HU P9902563 A HUP9902563 A HU P9902563A HU P9902563 A2 HUP9902563 A2 HU P9902563A2
- Authority
- HU
- Hungary
- Prior art keywords
- alkyl
- preparation
- aryl
- formula
- piperidine derivatives
- Prior art date
Links
- 150000003053 piperidines Chemical class 0.000 title abstract 2
- 239000000543 intermediate Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
- -1 piperidine compound Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- NQRYJNQNLNOLGT-UHFFFAOYSA-N tetrahydropyridine hydrochloride Natural products C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Preparation of piperidine derivatives of formula (I) or (II) comprises converting a regio-isomer of formula (III) to a compound (I) or (II) with a piperidine compound. In (I), X = C(O); in (II), X = CH(OH); n = 0 or 1; R1 = H or OH; R2 = H; or when n = 0, R1+R2 = a second C-C bond, provided that when n=1, R1 = R2 = H; R3 = COOH or COOR4 ; R4 = alkyl or aryl; A, B, D = H, halo, alkyl, OH, alkoxy or another substituent; Z = CG1G2G3 or a group of formula (a) or (b); m = 1-6; Q, Y = O, S or NR5; G1, G2, G3 = OR8, SR8 or NR8R9; R6, R7 = H, alkyl, aryl, OR8, SR8 or NR8R9; and R5, R8, R9 = H, alkyl or aryl. Compounds of formulae (III), (IV), (IX), (XIX), (XXV) and (XXVI) are new. ((XXV) = (I) with R3 replaced by Z; (XXVI) = (II) with R3 replaced by Z).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9902563A HUP9902563A3 (en) | 1996-12-19 | 1996-12-19 | Piperidine derivatives, intermediates, preparation and use thereof |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1996/020189 WO1997023213A1 (en) | 1995-12-21 | 1996-12-19 | Process for production of piperidine derivatives |
| HU9902563A HUP9902563A3 (en) | 1996-12-19 | 1996-12-19 | Piperidine derivatives, intermediates, preparation and use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP9902563A2 true HUP9902563A2 (en) | 1999-12-28 |
| HUP9902563A3 HUP9902563A3 (en) | 2001-10-29 |
Family
ID=89998890
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9902563A HUP9902563A3 (en) | 1996-12-19 | 1996-12-19 | Piperidine derivatives, intermediates, preparation and use thereof |
Country Status (1)
| Country | Link |
|---|---|
| HU (1) | HUP9902563A3 (en) |
-
1996
- 1996-12-19 HU HU9902563A patent/HUP9902563A3/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUP9902563A3 (en) | 2001-10-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB9A | Succession in title |
Owner name: ALBANY MOLECULAR RESEARCH, INC., US Free format text: FORMER OWNER(S): AMR TECHNOLOGY, INC., US; ALBANY MOLECULAR RESEARCH, INC., US |
|
| FH91 | Appointment of a representative |
Free format text: FORMER REPRESENTATIVE(S): IFJ. SZENTPETERI ADAM, S.B.G. & K. BUDAPESTI NEMZETKOEZI SZABADALMI IRODA, HU Representative=s name: DANUBIA SZABADALMI ES JOGI IRODA KFT., HU |
|
| FH92 | Termination of representative |
Representative=s name: IFJ. SZENTPETERI ADAM, S.B.G. & K. BUDAPESTI N, HU |
|
| FA9A | Lapse of provisional patent protection due to relinquishment or protection considered relinquished |