HUP9902452A1 - Probe for analysis of nucleic acids - Google Patents
Probe for analysis of nucleic acidsInfo
- Publication number
- HUP9902452A1 HUP9902452A1 HU9902452A HUP9902452A HUP9902452A1 HU P9902452 A1 HUP9902452 A1 HU P9902452A1 HU 9902452 A HU9902452 A HU 9902452A HU P9902452 A HUP9902452 A HU P9902452A HU P9902452 A1 HUP9902452 A1 HU P9902452A1
- Authority
- HU
- Hungary
- Prior art keywords
- probe
- sre
- binding
- nucleic acid
- analysis
- Prior art date
Links
- 150000007523 nucleic acids Chemical class 0.000 title abstract 5
- 102000039446 nucleic acids Human genes 0.000 title abstract 4
- 108020004707 nucleic acids Proteins 0.000 title abstract 4
- 239000000523 sample Substances 0.000 title abstract 4
- 125000006853 reporter group Chemical group 0.000 abstract 6
- 230000008863 intramolecular interaction Effects 0.000 abstract 2
- 230000004075 alteration Effects 0.000 abstract 1
- ANRHNWWPFJCPAZ-UHFFFAOYSA-M thionine Chemical class [Cl-].C1=CC(N)=CC2=[S+]C3=CC(N)=CC=C3N=C21 ANRHNWWPFJCPAZ-UHFFFAOYSA-M 0.000 abstract 1
Abstract
A probe for target nucleic acid sequences comprises a sequence recognising element (SRE) covalently bound to a reporter group (RG) whose signal properties are considerably altered when it binds to nucleic acid (NA). The probe (i) at least in its part nearest to the RG, has a structure such that any intramolecular interaction between the SRE and RG is suppressed, or such that this intramolecular interaction minimally affects the signal properties, and/or (ii) upon binding to target sequences, creates a structure that increases the signal alteration caused by the binding of the RG to NA. Also claimed are three specific groups of asymmetric cyanine compounds which can be used as reporter groups in the above probe.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU9902452A HUP9902452A3 (en) | 1997-05-30 | 1997-05-30 | Probe for analysis of nucleic acids |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU9902452A HUP9902452A3 (en) | 1997-05-30 | 1997-05-30 | Probe for analysis of nucleic acids |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP9902452A1 true HUP9902452A1 (en) | 2000-02-28 |
HUP9902452A3 HUP9902452A3 (en) | 2001-04-28 |
Family
ID=89998807
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9902452A HUP9902452A3 (en) | 1997-05-30 | 1997-05-30 | Probe for analysis of nucleic acids |
Country Status (1)
Country | Link |
---|---|
HU (1) | HUP9902452A3 (en) |
-
1997
- 1997-05-30 HU HU9902452A patent/HUP9902452A3/en unknown
Also Published As
Publication number | Publication date |
---|---|
HUP9902452A3 (en) | 2001-04-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |