HUP9902420A2 - 3-[(1,2,3,4-tetrahydroisoquinoline-2-yl)methyl]-8-azabicyclo[3,2,1]octane derivatives, their preparation and medicaments containing the same - Google Patents
3-[(1,2,3,4-tetrahydroisoquinoline-2-yl)methyl]-8-azabicyclo[3,2,1]octane derivatives, their preparation and medicaments containing the sameInfo
- Publication number
- HUP9902420A2 HUP9902420A2 HU9902420A HUP9902420A HUP9902420A2 HU P9902420 A2 HUP9902420 A2 HU P9902420A2 HU 9902420 A HU9902420 A HU 9902420A HU P9902420 A HUP9902420 A HU P9902420A HU P9902420 A2 HUP9902420 A2 HU P9902420A2
- Authority
- HU
- Hungary
- Prior art keywords
- tetrahydroisoquinoline
- azabicyclo
- methyl
- preparation
- same
- Prior art date
Links
- UECAYLDMIDGWPE-UHFFFAOYSA-N 2-(8-azabicyclo[3.2.1]octan-3-ylmethyl)-3,4-dihydro-1h-isoquinoline Chemical class C1CC2=CC=CC=C2CN1CC1CC(N2)CCC2C1 UECAYLDMIDGWPE-UHFFFAOYSA-N 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- -1 2-methoxyethoxy Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000001475 halogen functional group Chemical group 0.000 abstract 3
- IHXWLVHWFQATDJ-UHFFFAOYSA-N C1(NCCC2=CC=CC=C12)CC1N2CCC(CC1)C2 Chemical class C1(NCCC2=CC=CC=C12)CC1N2CCC(CC1)C2 IHXWLVHWFQATDJ-UHFFFAOYSA-N 0.000 abstract 1
- 125000001301 ethoxy group Chemical group [H]C([H])([H])C([H])([H])O* 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Tetrahydroisoquinolinylmethylazabicyclo[3.2.1]octane derivatives of formula (I), their salts and optical isomers are new. R1- R3 = H, halo, OH, 1-4C alkyl or 1-4C alkoxy; R4 = H, halo, 1-4C alkyl, 2-methoxyethoxy, 1-6C alkoxy, 3-6C cycloalkylmethoxy or phenylmethoxy; or R3+R4 = methylenedioxy; Z = O or (H,H); R = ethoxy (when Z is O) or phenyl (optionally substituted by one or more halo, 1-4C alkyl, 1-4C alkoxy or amino).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9902420A HUP9902420A3 (en) | 1997-04-10 | 1997-04-10 | 3-[(1,2,3,4-tetrahydroisoquinoline-2-yl)methyl]-8-azabicyclo[3,2,1]octane derivatives, their preparation and medicaments containing the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9902420A HUP9902420A3 (en) | 1997-04-10 | 1997-04-10 | 3-[(1,2,3,4-tetrahydroisoquinoline-2-yl)methyl]-8-azabicyclo[3,2,1]octane derivatives, their preparation and medicaments containing the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP9902420A2 true HUP9902420A2 (en) | 1999-12-28 |
| HUP9902420A3 HUP9902420A3 (en) | 2000-01-28 |
Family
ID=89998789
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9902420A HUP9902420A3 (en) | 1997-04-10 | 1997-04-10 | 3-[(1,2,3,4-tetrahydroisoquinoline-2-yl)methyl]-8-azabicyclo[3,2,1]octane derivatives, their preparation and medicaments containing the same |
Country Status (1)
| Country | Link |
|---|---|
| HU (1) | HUP9902420A3 (en) |
-
1997
- 1997-04-10 HU HU9902420A patent/HUP9902420A3/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUP9902420A3 (en) | 2000-01-28 |
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