HUP1500577A2 - New polymorph and solvate of idelalisib - Google Patents

New polymorph and solvate of idelalisib

Info

Publication number
HUP1500577A2
HUP1500577A2 HU1500577A HUP1500577A HUP1500577A2 HU P1500577 A2 HUP1500577 A2 HU P1500577A2 HU 1500577 A HU1500577 A HU 1500577A HU P1500577 A HUP1500577 A HU P1500577A HU P1500577 A2 HUP1500577 A2 HU P1500577A2
Authority
HU
Hungary
Prior art keywords
idelalisib
solvate
new polymorph
polymorph
new
Prior art date
Application number
HU1500577A
Other languages
Hungarian (hu)
Inventor
Endrene Florian
Detrich Adam Dezsoe Dr
Jozsef Kovacs
Karoly Lozsi
Gregor Tamas Dr
Zoltan Varga
Simig Gyula Dr
Fadgyas Katalin Kataine
Volk Balazs Dr
Porcs-Makkay Marta Dr
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Priority to HU1500577A priority Critical patent/HU231016B1/en
Priority to PCT/HU2016/050031 priority patent/WO2017093773A1/en
Publication of HUP1500577A2 publication Critical patent/HUP1500577A2/en
Publication of HU231016B1 publication Critical patent/HU231016B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
HU1500577A 2015-11-30 2015-11-30 New polymorph and solvate of idelalisib HU231016B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
HU1500577A HU231016B1 (en) 2015-11-30 2015-11-30 New polymorph and solvate of idelalisib
PCT/HU2016/050031 WO2017093773A1 (en) 2015-11-30 2016-07-01 New polymorphic and solvate form of idelalisib

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU1500577A HU231016B1 (en) 2015-11-30 2015-11-30 New polymorph and solvate of idelalisib

Publications (2)

Publication Number Publication Date
HUP1500577A2 true HUP1500577A2 (en) 2017-06-28
HU231016B1 HU231016B1 (en) 2019-11-28

Family

ID=89992005

Family Applications (1)

Application Number Title Priority Date Filing Date
HU1500577A HU231016B1 (en) 2015-11-30 2015-11-30 New polymorph and solvate of idelalisib

Country Status (2)

Country Link
HU (1) HU231016B1 (en)
WO (1) WO2017093773A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019178596A1 (en) 2018-03-16 2019-09-19 Johnson Matthey Public Limited Company Pyridine or n,n-dimethyl acetamide solvated solid state forms of solvated idelalisib, their use and preparation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005245875C1 (en) * 2004-05-13 2017-08-31 Icos Corporation Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta
WO2013134288A1 (en) * 2012-03-05 2013-09-12 Gilead Calistoga Llc Polymorphic forms of (s)-2-(1-(9h-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3h)-one
WO2015014315A1 (en) * 2013-08-01 2015-02-05 杭州普晒医药科技有限公司 Inhibitor crystalline form and preparation method and use thereof
CN104130261B (en) * 2014-08-04 2016-03-02 山东康美乐医药科技有限公司 The synthetic method of Chinese mugwort Delibes
CN104262344B (en) * 2014-08-22 2015-11-04 苏州明锐医药科技有限公司 The preparation method of Chinese mugwort Dana Delany

Also Published As

Publication number Publication date
HU231016B1 (en) 2019-11-28
WO2017093773A1 (en) 2017-06-08

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Legal Events

Date Code Title Description
MM4A Lapse of definitive patent protection due to non-payment of fees