HUP0400351A2 - Eljárás dialkil-3-oxo-glutarátok előállítására - Google Patents

Eljárás dialkil-3-oxo-glutarátok előállítására

Info

Publication number
HUP0400351A2
HUP0400351A2 HU0400351A HUP0400351A HUP0400351A2 HU P0400351 A2 HUP0400351 A2 HU P0400351A2 HU 0400351 A HU0400351 A HU 0400351A HU P0400351 A HUP0400351 A HU P0400351A HU P0400351 A2 HUP0400351 A2 HU P0400351A2
Authority
HU
Hungary
Prior art keywords
glutarates
oxo
producing dialkyl
citric acid
oxoglutarate
Prior art date
Application number
HU0400351A
Other languages
English (en)
Inventor
Elemér Jákfalvi
dr. Boros Lívia Gregorné
Tamás Mórász
Gábor Tóth
Attila Szabó
József Töreki
Sándor Oláh
Original Assignee
EGIS Gyógyszergyár Rt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EGIS Gyógyszergyár Rt. filed Critical EGIS Gyógyszergyár Rt.
Priority to HU0400351A priority Critical patent/HU227138B1/hu
Priority to ES04727059T priority patent/ES2318285T3/es
Priority to AT04727059T priority patent/ATE412625T1/de
Priority to PL04727059T priority patent/PL1615871T3/pl
Priority to DE602004017445T priority patent/DE602004017445D1/de
Priority to PCT/HU2004/000035 priority patent/WO2004089867A2/en
Priority to EP04727059A priority patent/EP1615871B1/en
Publication of HU0400351D0 publication Critical patent/HU0400351D0/hu
Publication of HUP0400351A2 publication Critical patent/HUP0400351A2/hu
Publication of HU227138B1 publication Critical patent/HU227138B1/hu

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A találmány tárgya eljárás az (I) általános képletű dialkil-3-oxo-glutarátok (mely képletben R jelentése metil- vagy etil-csoport)előállítására a (II) képletű citromsav vagy monohidrátja ésklórszulfonsav kis szénatomszámú klórozott alifás szénhidrogénbentörténő reagáltatása, majd a keletkező közbenső termék és metanol vagyetanol reakciója útján oly módon, hogy a kis szénatomszámú klórozottalifás szénhidrogént és a klórszulfonsavat 0,1:1-1:1 térfogataránybanalkalmazzák és a citromsavat 1-2 kg/perc sebességgel adják aklórszulfonsav és a kis szénatomszámú klórozott alifás szénhidrogénelegyéhez: Az (I) általános képletű dialkil-3-oxo-glutarátok értékesgyógyszeripari közbenső termékek.
HU0400351A 2003-04-10 2004-02-04 Method for producing dialkyl-3-oxo-glutarates HU227138B1 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
HU0400351A HU227138B1 (en) 2004-02-04 2004-02-04 Method for producing dialkyl-3-oxo-glutarates
ES04727059T ES2318285T3 (es) 2003-04-10 2004-04-13 Procedimiento para la preparacionb de 3-oxoglutaratos de dialquilo.
AT04727059T ATE412625T1 (de) 2003-04-10 2004-04-13 Verfahren zur herstellung von dialkyl 3- oxoglutaraten
PL04727059T PL1615871T3 (pl) 2003-04-10 2004-04-13 Sposób wytwarzania 3-oksoglutaranów dialkilowych
DE602004017445T DE602004017445D1 (de) 2003-04-10 2004-04-13 Verfahren zur herstellung von dialkyl 3-oxoglutaraten
PCT/HU2004/000035 WO2004089867A2 (en) 2003-04-10 2004-04-13 Process for the preparation of dialkyl 3-oxoglutarates
EP04727059A EP1615871B1 (en) 2003-04-10 2004-04-13 Process for the preparation of dialkyl 3-oxoglutarates

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU0400351A HU227138B1 (en) 2004-02-04 2004-02-04 Method for producing dialkyl-3-oxo-glutarates

Publications (3)

Publication Number Publication Date
HU0400351D0 HU0400351D0 (en) 2004-04-28
HUP0400351A2 true HUP0400351A2 (hu) 2005-10-28
HU227138B1 HU227138B1 (en) 2010-08-30

Family

ID=89981965

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0400351A HU227138B1 (en) 2003-04-10 2004-02-04 Method for producing dialkyl-3-oxo-glutarates

Country Status (1)

Country Link
HU (1) HU227138B1 (hu)

Also Published As

Publication number Publication date
HU227138B1 (en) 2010-08-30
HU0400351D0 (en) 2004-04-28

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HC9A Change of name, address

Owner name: EGIS GYOGYSZERGYAR NYRT., HU

Free format text: FORMER OWNER(S): EGIS GYOGYSZERGYAR RT., HU