HUP0203164A2 - Expression products of genes involved in diseases related to cholesterol metabolism - Google Patents
Expression products of genes involved in diseases related to cholesterol metabolismInfo
- Publication number
- HUP0203164A2 HUP0203164A2 HU0203164A HUP0203164A HUP0203164A2 HU P0203164 A2 HUP0203164 A2 HU P0203164A2 HU 0203164 A HU0203164 A HU 0203164A HU P0203164 A HUP0203164 A HU P0203164A HU P0203164 A2 HUP0203164 A2 HU P0203164A2
- Authority
- HU
- Hungary
- Prior art keywords
- subject
- nucleic acids
- genes involved
- diseases related
- expression products
- Prior art date
Links
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title abstract 4
- 230000004060 metabolic process Effects 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 abstract 3
- 102000039446 nucleic acids Human genes 0.000 abstract 3
- 150000007523 nucleic acids Chemical class 0.000 abstract 3
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090001030 Lipoproteins Proteins 0.000 abstract 1
- 102000004895 Lipoproteins Human genes 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 235000012000 cholesterol Nutrition 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
A találmány tárgyát olyan génekből expresszálódott nukleinsavakképezik, amelyek a humán genom olyan régióiban helyezkednek el,amelyek plazma-lipoproteinek metabolizmusával társult állapotokban,pontosabban koleszterin reverz transzportjában játszanak szerepet. Atalálmány tárgyát képezik olyan polipeptidek is, amelyeket az említettnukleinsavak közül néhány kódol, valamint specifikusan ilyenpolipeptidek ellen termeltetett antitestek, amelyek diagnosztikaireagensként alkalmazhatók. Végül a találmány tárgyát képezik ilyennukleinsavakat vagy fragmentumait tartalmazó vektorok és rekombinánsgazdasejtek. ÓThe subject of the invention is nucleic acids expressed from genes that are located in regions of the human genome that play a role in conditions associated with the metabolism of plasma lipoproteins, more specifically in the reverse transport of cholesterol. The subject of the invention are also polypeptides encoded by some of the mentioned nucleic acids, as well as antibodies produced specifically against such polypeptides, which can be used as diagnostic reagents. Finally, the subject of the invention is vectors and recombinant host cells containing such nucleic acids or their fragments. HE
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9906587A FR2794131B1 (en) | 1999-05-25 | 1999-05-25 | GENE EXPRESSION PRODUCTS INVOLVED IN CONDITIONS ASSOCIATED WITH THE METABOLISM OF CHOLESTEROL |
| US13945099P | 1999-06-16 | 1999-06-16 | |
| PCT/FR2000/001426 WO2000071710A2 (en) | 1999-05-25 | 2000-05-25 | Expression products of genes involved in diseases related to cholesterol metabolism |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUP0203164A2 true HUP0203164A2 (en) | 2002-12-28 |
Family
ID=26234967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0203164A HUP0203164A2 (en) | 1999-05-25 | 2000-05-25 | Expression products of genes involved in diseases related to cholesterol metabolism |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1183350A2 (en) |
| JP (1) | JP2003518918A (en) |
| KR (1) | KR20020033627A (en) |
| AU (1) | AU4931800A (en) |
| BR (1) | BR0010916A (en) |
| CA (1) | CA2371500A1 (en) |
| HU (1) | HUP0203164A2 (en) |
| IL (1) | IL145835A0 (en) |
| MX (1) | MXPA01011882A (en) |
| NO (1) | NO20015729L (en) |
| WO (1) | WO2000071710A2 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1100895T1 (en) | 1999-03-15 | 2001-09-06 | The University Of British Columbia, Vancouver | ABC1 POLYPEPTIDES AND METHODS AND REAGENTS FOR MODULATING THE CHOLESTEROL CONTENT |
| MXPA03000979A (en) * | 2000-08-01 | 2004-08-12 | Amgen Inc | C3b/C4b COMPLEMENT RECEPTOR-LIKE MOLECULES AND USES THEREOF. |
| AT413701B (en) * | 2001-11-06 | 2006-05-15 | Bmt Medizinische Forschung Und | STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF CDW92 |
| EP2123676A4 (en) * | 2007-01-05 | 2011-01-05 | Univ Tokyo | Diagnosis and treatment of cancer by using anti-prg-3 antibody |
| CN102112492B (en) | 2007-11-14 | 2015-02-25 | 中外制药株式会社 | Diagnosis and treatment of cancer using anti-GPR49 antibody |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0941366A2 (en) * | 1996-11-06 | 1999-09-15 | Whitehead Institute For Biomedical Research | Biallelic markers |
-
2000
- 2000-05-25 CA CA002371500A patent/CA2371500A1/en not_active Abandoned
- 2000-05-25 JP JP2000620087A patent/JP2003518918A/en not_active Withdrawn
- 2000-05-25 AU AU49318/00A patent/AU4931800A/en not_active Abandoned
- 2000-05-25 MX MXPA01011882A patent/MXPA01011882A/en unknown
- 2000-05-25 IL IL14583500A patent/IL145835A0/en unknown
- 2000-05-25 KR KR1020017015017A patent/KR20020033627A/en not_active Application Discontinuation
- 2000-05-25 BR BR0010916-9A patent/BR0010916A/en not_active IP Right Cessation
- 2000-05-25 HU HU0203164A patent/HUP0203164A2/en unknown
- 2000-05-25 EP EP00931354A patent/EP1183350A2/en not_active Withdrawn
- 2000-05-25 WO PCT/FR2000/001426 patent/WO2000071710A2/en not_active Application Discontinuation
-
2001
- 2001-11-23 NO NO20015729A patent/NO20015729L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU4931800A (en) | 2000-12-12 |
| BR0010916A (en) | 2002-02-19 |
| JP2003518918A (en) | 2003-06-17 |
| EP1183350A2 (en) | 2002-03-06 |
| MXPA01011882A (en) | 2002-05-06 |
| IL145835A0 (en) | 2002-07-25 |
| CA2371500A1 (en) | 2000-11-30 |
| WO2000071710A3 (en) | 2001-05-17 |
| NO20015729D0 (en) | 2001-11-23 |
| NO20015729L (en) | 2002-01-22 |
| KR20020033627A (en) | 2002-05-07 |
| WO2000071710A2 (en) | 2000-11-30 |
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