HUP0203152A2 - Method and compositions for treating pulmonary diseases - Google Patents
Method and compositions for treating pulmonary diseasesInfo
- Publication number
- HUP0203152A2 HUP0203152A2 HU0203152A HUP0203152A HUP0203152A2 HU P0203152 A2 HUP0203152 A2 HU P0203152A2 HU 0203152 A HU0203152 A HU 0203152A HU P0203152 A HUP0203152 A HU P0203152A HU P0203152 A2 HUP0203152 A2 HU P0203152A2
- Authority
- HU
- Hungary
- Prior art keywords
- pulmonary diseases
- compositions
- treating pulmonary
- reducing
- methods
- Prior art date
Links
- 208000019693 Lung disease Diseases 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 3
- MSYGAHOHLUJIKV-UHFFFAOYSA-N 3,5-dimethyl-1-(3-nitrophenyl)-1h-pyrazole-4-carboxylic acid ethyl ester Chemical compound CC1=C(C(=O)OCC)C(C)=NN1C1=CC=CC([N+]([O-])=O)=C1 MSYGAHOHLUJIKV-UHFFFAOYSA-N 0.000 abstract 2
- 102000011017 Type 4 Cyclic Nucleotide Phosphodiesterases Human genes 0.000 abstract 2
- 108010037584 Type 4 Cyclic Nucleotide Phosphodiesterases Proteins 0.000 abstract 2
- 229940123932 Phosphodiesterase 4 inhibitor Drugs 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000003246 corticosteroid Substances 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000002587 phosphodiesterase IV inhibitor Substances 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A találmány pulmonalis betegségek tüneteinek megelőzésére vagycsökkentésére, illetve a pulmonalis betegségek súlyosságánakkezelésére vagy csökkentésére szolgáló kompozíciókra és eljárásokravonatkozik. Közelebbről a találmány foszfodiészteráz-4(PDE4) általmediált pulmonalis betegségek kezelésére szolgáló kompozíciókra éseljárásokra vonatkozik, ahol az eljárás során egy gyulladáselleneskortiko<- >szteroiddal együtt adnak be egy PDE4 inhibitort. ÓThe invention relates to compositions and methods for preventing or reducing the symptoms of pulmonary diseases, or treating or reducing the severity of pulmonary diseases. More specifically, the invention relates to compositions and methods for the treatment of pulmonary diseases mediated by phosphodiesterase-4 (PDE4), where a PDE4 inhibitor is administered together with an anti-inflammatory corticosteroid. HE
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16315899P | 1999-11-02 | 1999-11-02 | |
| PCT/US2000/030113 WO2001032127A2 (en) | 1999-11-02 | 2000-11-01 | Method and compositions for treating pulmonary diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0203152A2 true HUP0203152A2 (en) | 2003-01-28 |
| HUP0203152A3 HUP0203152A3 (en) | 2004-06-28 |
Family
ID=22588737
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0203152A HUP0203152A3 (en) | 1999-11-02 | 2000-11-01 | Method and compositions for treating pulmonary diseases |
Country Status (29)
| Country | Link |
|---|---|
| EP (1) | EP1225866A4 (en) |
| JP (1) | JP2003513028A (en) |
| KR (1) | KR20020057988A (en) |
| CN (1) | CN1387404A (en) |
| AP (1) | AP2002002496A0 (en) |
| AR (1) | AR029189A1 (en) |
| AU (1) | AU1357501A (en) |
| BG (1) | BG106748A (en) |
| BR (1) | BR0015270A (en) |
| CA (1) | CA2388333A1 (en) |
| CO (1) | CO5261512A1 (en) |
| CZ (1) | CZ20021512A3 (en) |
| DZ (1) | DZ3225A1 (en) |
| EA (1) | EA200200518A1 (en) |
| EC (1) | ECSP003747A (en) |
| HK (1) | HK1049107A1 (en) |
| HU (1) | HUP0203152A3 (en) |
| IL (1) | IL149367A0 (en) |
| MA (1) | MA26841A1 (en) |
| MX (1) | MXPA02004350A (en) |
| NO (1) | NO20022057L (en) |
| OA (1) | OA12076A (en) |
| PE (1) | PE20011005A1 (en) |
| PL (1) | PL355261A1 (en) |
| SK (1) | SK7592002A3 (en) |
| TR (1) | TR200201211T2 (en) |
| TW (1) | TWI242431B (en) |
| WO (1) | WO2001032127A2 (en) |
| ZA (1) | ZA200203435B (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60218497T2 (en) * | 2001-09-19 | 2007-11-08 | Nycomed Gmbh | COMBINATION OF A NSAID AND A PDE-4 INHIBITOR |
| SK1862004A3 (en) * | 2001-10-31 | 2004-08-03 | Type 4 phosphodiesterase inhibitors and uses thereof | |
| UA82323C2 (en) * | 2002-08-09 | 2008-04-10 | Меда Фарма Гмбх & Ко. Кг | Novel combination of a glucocorticoid and pde-inhibitor for the treatment of respiratory diseases, allergic diseases, asthma and chronic obstructive pulmonary diseases |
| TW200410923A (en) * | 2002-10-17 | 2004-07-01 | Ono Pharmaceutical Co | Therapeutic agent for chronic obstructive pulmonary disease |
| EP1616569A1 (en) * | 2003-03-31 | 2006-01-18 | Kyowa Hakko Kogyo Co., Ltd. | Medicinal composition |
| US20050026883A1 (en) * | 2003-07-31 | 2005-02-03 | Robinson Cynthia B. | Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a PDE-4 inhibitor for treatment of asthma or chronic obstructive pulmonary disease |
| CA2584169A1 (en) * | 2004-10-13 | 2006-04-20 | Kyowa Hakko Kogyo Co., Ltd. | Remedies/preventives for chronic skin disease |
| WO2007045980A1 (en) * | 2005-10-19 | 2007-04-26 | Ranbaxy Laboratories Limited | Compositions of phosphodiesterase type iv inhibitors |
| EP3431128A1 (en) | 2010-01-05 | 2019-01-23 | MicroDose Therapeutx, Inc. | Inhalation device and method |
| WO2015063669A1 (en) | 2013-10-30 | 2015-05-07 | Wockhardt Limited | Pharmaceutical compositions comprising combination of roflumilast and acebrophylline or pharmaceutically acceptable salts thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT710109E (en) * | 1993-06-18 | 2005-01-31 | Smithkline Beecham Corp | METHOD FOR IDENTIFYING A PDE IV INHIBITOR |
| DE4332041C2 (en) * | 1993-09-21 | 1997-12-11 | Rentschler Arzneimittel | Use of pentoxifylline in certain lung diseases |
| PE44995A1 (en) * | 1994-01-27 | 1995-12-18 | Schering Corp | MOMETASONE FUROATE FOR THE TREATMENT OF LUNG DISEASES AND RESPIRATORY TRACT |
| SE9801368D0 (en) * | 1998-04-20 | 1998-04-20 | Astra Ab | New use |
-
2000
- 2000-10-31 EC EC2000003747A patent/ECSP003747A/en unknown
- 2000-10-31 AR ARP000105742A patent/AR029189A1/en not_active Application Discontinuation
- 2000-11-01 JP JP2001534335A patent/JP2003513028A/en active Pending
- 2000-11-01 CN CN00815265A patent/CN1387404A/en active Pending
- 2000-11-01 WO PCT/US2000/030113 patent/WO2001032127A2/en active Search and Examination
- 2000-11-01 AU AU13575/01A patent/AU1357501A/en not_active Abandoned
- 2000-11-01 HU HU0203152A patent/HUP0203152A3/en unknown
- 2000-11-01 AP APAP/P/2002/002496A patent/AP2002002496A0/en unknown
- 2000-11-01 SK SK759-2002A patent/SK7592002A3/en unknown
- 2000-11-01 CZ CZ20021512A patent/CZ20021512A3/en unknown
- 2000-11-01 IL IL14936700A patent/IL149367A0/en unknown
- 2000-11-01 DZ DZ003225A patent/DZ3225A1/en active
- 2000-11-01 PL PL00355261A patent/PL355261A1/en not_active Application Discontinuation
- 2000-11-01 TR TR2002/01211T patent/TR200201211T2/en unknown
- 2000-11-01 BR BR0015270-6A patent/BR0015270A/en not_active IP Right Cessation
- 2000-11-01 KR KR1020027005609A patent/KR20020057988A/en not_active Application Discontinuation
- 2000-11-01 EA EA200200518A patent/EA200200518A1/en unknown
- 2000-11-01 OA OA1200200124A patent/OA12076A/en unknown
- 2000-11-01 MX MXPA02004350A patent/MXPA02004350A/en unknown
- 2000-11-01 CA CA002388333A patent/CA2388333A1/en not_active Abandoned
- 2000-11-01 EP EP00975533A patent/EP1225866A4/en not_active Withdrawn
- 2000-11-02 CO CO00083427A patent/CO5261512A1/en not_active Application Discontinuation
- 2000-11-02 PE PE2000001168A patent/PE20011005A1/en not_active Application Discontinuation
- 2000-11-22 TW TW089123039A patent/TWI242431B/en not_active IP Right Cessation
-
2002
- 2002-04-30 NO NO20022057A patent/NO20022057L/en not_active Application Discontinuation
- 2002-04-30 ZA ZA200203435A patent/ZA200203435B/en unknown
- 2002-05-02 MA MA26621A patent/MA26841A1/en unknown
- 2002-05-29 BG BG106748A patent/BG106748A/en unknown
- 2002-12-19 HK HK02109234.5A patent/HK1049107A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL149367A0 (en) | 2002-11-10 |
| BR0015270A (en) | 2002-06-18 |
| CO5261512A1 (en) | 2003-03-31 |
| AP2002002496A0 (en) | 2002-06-30 |
| DZ3225A1 (en) | 2001-05-10 |
| JP2003513028A (en) | 2003-04-08 |
| WO2001032127A2 (en) | 2001-05-10 |
| ZA200203435B (en) | 2003-06-25 |
| BG106748A (en) | 2003-02-28 |
| HUP0203152A3 (en) | 2004-06-28 |
| EP1225866A2 (en) | 2002-07-31 |
| CA2388333A1 (en) | 2001-05-10 |
| PL355261A1 (en) | 2004-04-05 |
| AR029189A1 (en) | 2003-06-18 |
| NO20022057L (en) | 2002-06-27 |
| OA12076A (en) | 2006-05-04 |
| KR20020057988A (en) | 2002-07-12 |
| TWI242431B (en) | 2005-11-01 |
| MXPA02004350A (en) | 2002-11-07 |
| SK7592002A3 (en) | 2002-11-06 |
| AU1357501A (en) | 2001-05-14 |
| EP1225866A4 (en) | 2004-04-21 |
| EA200200518A1 (en) | 2002-10-31 |
| CZ20021512A3 (en) | 2003-04-16 |
| TR200201211T2 (en) | 2002-08-21 |
| CN1387404A (en) | 2002-12-25 |
| PE20011005A1 (en) | 2001-09-28 |
| ECSP003747A (en) | 2002-05-23 |
| NO20022057D0 (en) | 2002-04-30 |
| HK1049107A1 (en) | 2003-05-02 |
| MA26841A1 (en) | 2004-12-20 |
| WO2001032127A3 (en) | 2001-12-06 |
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