HUP0200337A2 - Stabilised pharmaceutical composition comprising pravastatin sodium - Google Patents

Stabilised pharmaceutical composition comprising pravastatin sodium

Info

Publication number
HUP0200337A2
HUP0200337A2 HU0200337A HUP0200337A HUP0200337A2 HU P0200337 A2 HUP0200337 A2 HU P0200337A2 HU 0200337 A HU0200337 A HU 0200337A HU P0200337 A HUP0200337 A HU P0200337A HU P0200337 A2 HUP0200337 A2 HU P0200337A2
Authority
HU
Hungary
Prior art keywords
pravastatin sodium
pharmaceutical composition
stabilised pharmaceutical
stabilised
sodium
Prior art date
Application number
HU0200337A
Other languages
Hungarian (hu)
Inventor
Gabriella Ujhelyi
Máthé Irma Kálmánné
Antal Tóth
József Vas
Boglárka Jakab
Márta Venczel
Original Assignee
Sanofi-Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Aventis filed Critical Sanofi-Aventis
Priority to HU0200337A priority Critical patent/HUP0200337A2/en
Publication of HU0200337D0 publication Critical patent/HU0200337D0/en
Priority to PCT/HU2003/000006 priority patent/WO2003063836A1/en
Publication of HUP0200337A2 publication Critical patent/HUP0200337A2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

A találmány tárgya stabilizált gyógyászati készítmény, hatóanyagkéntpravastatin-nátriumot, stabilizálószerként valamely kelátképzésrealkalmas fém laktát sóját, és egy vagy több gyógyszerkészítésbenalkalmazott segédanyagot tartalmaz.The subject of the invention is a stabilized medicinal preparation, containing pravastatin sodium as an active ingredient, a lactate salt of a chelating metal as a stabilizing agent, and one or more excipients used in pharmaceutical preparation.

HU0200337A 2002-01-30 2002-01-30 Stabilised pharmaceutical composition comprising pravastatin sodium HUP0200337A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
HU0200337A HUP0200337A2 (en) 2002-01-30 2002-01-30 Stabilised pharmaceutical composition comprising pravastatin sodium
PCT/HU2003/000006 WO2003063836A1 (en) 2002-01-30 2003-01-28 Stable pharmaceutical composition comprising pravastatin sodium

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU0200337A HUP0200337A2 (en) 2002-01-30 2002-01-30 Stabilised pharmaceutical composition comprising pravastatin sodium

Publications (2)

Publication Number Publication Date
HU0200337D0 HU0200337D0 (en) 2002-03-28
HUP0200337A2 true HUP0200337A2 (en) 2005-09-28

Family

ID=89980110

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0200337A HUP0200337A2 (en) 2002-01-30 2002-01-30 Stabilised pharmaceutical composition comprising pravastatin sodium

Country Status (2)

Country Link
HU (1) HUP0200337A2 (en)
WO (1) WO2003063836A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8163797B2 (en) * 2003-12-31 2012-04-24 Actavis Elizabeth Llc Method of treating with stable pravastatin formulation
KR101683635B1 (en) 2014-12-29 2016-12-09 가천대학교 산학협력단 Pharmaceutical composition for treating cancer comprising lactate metallic salts
MX2020007462A (en) 2018-01-12 2020-09-14 Metimedi Pharmaceuticals Co Ltd Methods of treating chronic inflammatory diseases.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000229855A (en) * 1998-12-07 2000-08-22 Satoshi Takebe Pravastatin sodium tablet
WO2001097800A1 (en) * 2000-06-23 2001-12-27 Sankyo Company, Limited Method of stabilizing medicinal compositions containing pravastatin

Also Published As

Publication number Publication date
WO2003063836A1 (en) 2003-08-07
HU0200337D0 (en) 2002-03-28

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees