HUP0101153A2 - Desaturase - Google Patents

Desaturase

Info

Publication number
HUP0101153A2
HUP0101153A2 HU0101153A HUP0101153A HUP0101153A2 HU P0101153 A2 HUP0101153 A2 HU P0101153A2 HU 0101153 A HU0101153 A HU 0101153A HU P0101153 A HUP0101153 A HU P0101153A HU P0101153 A2 HUP0101153 A2 HU P0101153A2
Authority
HU
Hungary
Prior art keywords
fatty acid
production
acid desaturases
desaturases
acid derivatives
Prior art date
Application number
HU0101153A
Other languages
Hungarian (hu)
Inventor
Louise Michaelson
Johnathan A. Napier
Keith Stobart
Original Assignee
University Of Bristol
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9727256.1A external-priority patent/GB9727256D0/en
Priority claimed from GBGB9814034.6A external-priority patent/GB9814034D0/en
Application filed by University Of Bristol filed Critical University Of Bristol
Publication of HUP0101153A2 publication Critical patent/HUP0101153A2/en
Publication of HUP0101153A3 publication Critical patent/HUP0101153A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • C12P7/6472Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083Miscellaneous (1.14.99)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Abstract

A találmány tárgyát D5-zsírsav deszaturázokat kódoló DNS-szekvenciák,a kódolt D5-zsírsav deszaturázok és a D5-zsírsav deszaturázokalkalmazásai képezik, politelítetlen zsírsavak és politelítetlenzsírsavakat tartalmazó táplálékkiegészítők előállítására. A találmányszerinti megoldás alkalmas egészségmegőrző és terápiás aktivitásútelítetlen zsírsavszármazékok, valamint ilyen zsírsavszármazékokattartalmazó készítmények előállítására. ÓThe subject of the invention is DNA sequences encoding D5-fatty acid desaturases, the encoded D5-fatty acid desaturases and the applications of D5-fatty acid desaturases for the production of polyunsaturated fatty acids and food supplements containing polyunsaturated fatty acids. The solution according to the invention is suitable for the production of health-preserving and therapeutically active unsaturated fatty acid derivatives and preparations containing such fatty acid derivatives. HE

HU0101153A 1997-12-23 1998-12-23 Desaturase HUP0101153A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9727256.1A GB9727256D0 (en) 1997-12-23 1997-12-23 Desaturase gene
GBGB9814034.6A GB9814034D0 (en) 1998-06-29 1998-06-29 Desaturase gene
PCT/GB1998/003895 WO1999033958A2 (en) 1997-12-23 1998-12-23 Desaturase

Publications (2)

Publication Number Publication Date
HUP0101153A2 true HUP0101153A2 (en) 2001-08-28
HUP0101153A3 HUP0101153A3 (en) 2006-03-28

Family

ID=26312844

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0101153A HUP0101153A3 (en) 1997-12-23 1998-12-23 Desaturase

Country Status (11)

Country Link
EP (1) EP1042485A2 (en)
JP (1) JP2002508932A (en)
KR (1) KR20010033517A (en)
CN (1) CN1283230A (en)
AU (1) AU1774899A (en)
BR (1) BR9814434A (en)
CA (1) CA2315297A1 (en)
EE (1) EE200000372A (en)
HU (1) HUP0101153A3 (en)
PL (1) PL344868A1 (en)
WO (1) WO1999033958A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8791327B2 (en) 1998-12-07 2014-07-29 Washington State University Research Foundation Desaturases and methods of using them for synthesis of polyunsaturated fatty acids
WO2001092489A2 (en) * 2000-05-26 2001-12-06 Washington State University Research Foundation Palmitate desaturase gene
CN105483142A (en) * 2000-09-28 2016-04-13 生物源食物及科学公司 FAD4, FAD5, FAD5-2, and FAD6, novel fatty acid desaturase family members and uses thereof
GB0107510D0 (en) 2001-03-26 2001-05-16 Univ Bristol New elongase gene and a process for the production of -9-polyunsaturated fatty acids
GB0229578D0 (en) * 2002-12-19 2003-01-22 Univ Bristol Novel method for the production of polyunsaturated fatty acids
GB0403452D0 (en) * 2004-02-17 2004-03-24 Univ York Desaturase enzymes
CN103451246B (en) 2004-04-22 2018-02-16 联邦科学技术研究组织 With recombinant cell synthesis of long-chain polyunsaturated fatty acids
EP2363492A3 (en) 2004-04-22 2012-03-14 Commonwealth Scientific and Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells.
PT1766023E (en) 2004-06-04 2010-12-09 Fluxome Sciences As Metabolically engineered cells for the production of polyunsaturated fatty acids
WO2006006710A1 (en) 2004-07-12 2006-01-19 Suntory Limited Polypeptide having δ5 fatty acid unsaturating activity, polynucleotide coding for the polypeptide, and use thereof
GB2431158A (en) * 2005-10-13 2007-04-18 Rothamsted Res Ltd Process for the production of arachidonic and/or eicosapentaenoic acid
US8816106B2 (en) 2006-08-29 2014-08-26 Commonwealth Scientific And Industrial Research Organisation Synthesis of fatty acids
CN101376020B (en) * 2007-08-29 2013-05-01 益生生技开发股份有限公司 Application of fungal immunomodulatory protein for inhibiting delta 5-desaturated enzyme
AR074364A1 (en) 2008-11-18 2011-01-12 Commw Scient Ind Res Org ENZYMES AND METHOD TO PRODUCE OMEGA FATTY ACIDS -3
EP3266316A1 (en) 2012-06-15 2018-01-10 Commonwealth Scientific and Industrial Research Organisation Production of long chain polyunsaturated fatty acids in plant cells
WO2015089587A1 (en) 2013-12-18 2015-06-25 Commonwealth Scientific And Industrial Research Organisation Lipid comprising long chain polyunsaturated fatty acids
CN105219789B (en) 2014-06-27 2023-04-07 联邦科学技术研究组织 Extracted plant lipids comprising docosapentaenoic acid

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5972664A (en) * 1997-04-11 1999-10-26 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids

Also Published As

Publication number Publication date
JP2002508932A (en) 2002-03-26
WO1999033958A2 (en) 1999-07-08
AU1774899A (en) 1999-07-19
EP1042485A2 (en) 2000-10-11
HUP0101153A3 (en) 2006-03-28
BR9814434A (en) 2001-10-23
CA2315297A1 (en) 1999-07-08
WO1999033958A3 (en) 1999-09-02
PL344868A1 (en) 2001-11-19
CN1283230A (en) 2001-02-07
EE200000372A (en) 2001-12-17
KR20010033517A (en) 2001-04-25

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees