HUP0002304A2 - The use of proteins extractable from animal organs for the preparation of medicaments for the treatment of pathological conditions characterized by hyperproduction of tumor necrosis factor (tnf) - Google Patents

The use of proteins extractable from animal organs for the preparation of medicaments for the treatment of pathological conditions characterized by hyperproduction of tumor necrosis factor (tnf)

Info

Publication number
HUP0002304A2
HUP0002304A2 HU0002304A HUP0002304A HUP0002304A2 HU P0002304 A2 HUP0002304 A2 HU P0002304A2 HU 0002304 A HU0002304 A HU 0002304A HU P0002304 A HUP0002304 A HU P0002304A HU P0002304 A2 HUP0002304 A2 HU P0002304A2
Authority
HU
Hungary
Prior art keywords
tnf
treatment
necrosis factor
tumor necrosis
pathological conditions
Prior art date
Application number
HU0002304A
Other languages
Hungarian (hu)
Inventor
Alberto Bartorelli
Pier Luigi Meroni
Alberto Panerai
Original Assignee
Zetesis S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zetesis S.P.A. filed Critical Zetesis S.P.A.
Publication of HUP0002304A2 publication Critical patent/HUP0002304A2/en
Publication of HUP0002304A3 publication Critical patent/HUP0002304A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A találmány tárgyát emlősök májából, különösen kecskemájbólperklórsavval kivonható fehérjék képezik. A találmány szerintifehérjék csökkentik a vér tumornekrózis-faktor (TNF)-szintjét, ésalkalmasak sclerosis multiplex, rheumatoid arthritis, szeptikus sokkvagy más, TNF- túltermelődéssel jellemezhető kóros állapotokkezelésére. ÓThe subject of the invention are proteins that can be extracted from the liver of mammals, especially goat liver, with perchloric acid. The proteins according to the invention reduce the level of tumor necrosis factor (TNF) in the blood and are suitable for the treatment of multiple sclerosis, rheumatoid arthritis, septic shock or other pathological conditions characterized by TNF- overproduction. HE

HU0002304A 1997-03-25 1998-03-16 The use of proteins extractable from animal organs for the preparation of medicaments for the treatment of pathological conditions characterized by hyperproduction of tumor necrosis factor (tnf) HUP0002304A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97MI000694A IT1290828B1 (en) 1997-03-25 1997-03-25 USE OF EXTRACTABLE PROTEINS FROM ANIMAL ORGANS FOR THE PREPARATION OF MEDICATIONS FOR THE TREATMENT OF PATHOLOGICAL CONDITIONS

Publications (2)

Publication Number Publication Date
HUP0002304A2 true HUP0002304A2 (en) 2000-11-28
HUP0002304A3 HUP0002304A3 (en) 2001-12-28

Family

ID=11376611

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0002304A HUP0002304A3 (en) 1997-03-25 1998-03-16 The use of proteins extractable from animal organs for the preparation of medicaments for the treatment of pathological conditions characterized by hyperproduction of tumor necrosis factor (tnf)

Country Status (16)

Country Link
US (1) US6255283B1 (en)
EP (1) EP0969859A1 (en)
JP (1) JP2001518107A (en)
KR (1) KR20010005705A (en)
CN (1) CN1251043A (en)
AU (1) AU7207298A (en)
BR (1) BR9808625A (en)
CA (1) CA2284548A1 (en)
HU (1) HUP0002304A3 (en)
IL (1) IL132013A0 (en)
IT (1) IT1290828B1 (en)
NO (1) NO994622D0 (en)
NZ (1) NZ337985A (en)
PL (1) PL335829A1 (en)
TR (1) TR199902331T2 (en)
WO (1) WO1998042366A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001262340A1 (en) * 2000-06-08 2001-12-17 Rakepoll Holding B.V. A method of treatment of parkinson's disease with a protein extractable from mammalian organs
US20030153511A1 (en) * 2000-06-08 2003-08-14 Alberto Panerai Method of treatment of huntington's chorea with a protein extractable from mammalian organs
JP2003535139A (en) * 2000-06-08 2003-11-25 レイクポール ホールディング ビー．ブイ． Method for treating amyotrophic lateral sclerosis using proteins extractable from mammalian organs
US20030165492A1 (en) * 2000-06-08 2003-09-04 Alberto Panerai Method of treatment of alzheimer's disease with a protein extractable from mammalian organs
ITMI20010762A1 (en) * 2001-04-10 2002-10-10 Zetesis Spa USE OF UK114 PROTEIN OR ITS FRAGMENTS FOR THE TREATMENT AND PREVENTION OF ENDOTOXIC SHOCK
ITMI20021205A1 (en) * 2002-06-04 2003-12-04 Pharmaproducts Uk Ltd USE OF PROTEINS FOR THE TREATMENT OF LEISHMANIOSIS
IT201600127428A1 (en) * 2016-12-16 2018-06-16 Cusani Alberto Bartorelli NEW RECOMBINANT UK 114 PROTEIN IN STABLE POLYMER FORM FOR USE IN THERAPY, IN DIAGNOSTICS AND IN THE PREVENTION OF MALIGNE NEOPLASIA

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2251186A (en) 1990-12-04 1992-07-01 Randall Neal Gatz Polypeptide for use in treatment of autoimmune disease
FR2688227A1 (en) * 1992-03-04 1993-09-10 Inst Nat Sante Rech Med PROTEINS FORMING COMPLEXES WITH CHAPERONES AND THEIR LIGANDS, THEIR FRAGMENTS, THEIR PRODUCTION AND THEIR BIOLOGICAL APPLICATIONS.
US5997873A (en) * 1994-01-13 1999-12-07 Mount Sinai School Of Medicine Of The City University Of New York Method of preparation of heat shock protein 70-peptide complexes
IT1270618B (en) 1994-07-14 1997-05-07 Zetesis Spa PROTEIN WITH ANTI-TUMOR ACTIVITY
GB9419553D0 (en) 1994-09-27 1994-11-16 Univ Bristol Polypeptides and their use in the treatment of auto-immune disease
DK0928197T3 (en) 1996-09-18 2003-06-23 Zetesis Spa Use of proteins as agents for autoimmune diseases
US6007821A (en) * 1997-10-16 1999-12-28 Fordham University Method and compositions for the treatment of autoimmune disease using heat shock proteins

Also Published As

Publication number Publication date
BR9808625A (en) 2000-05-16
CA2284548A1 (en) 1998-10-01
IT1290828B1 (en) 1998-12-11
NO994622L (en) 1999-09-23
WO1998042366A1 (en) 1998-10-01
IL132013A0 (en) 2001-03-19
HUP0002304A3 (en) 2001-12-28
TR199902331T2 (en) 2000-01-21
AU7207298A (en) 1998-10-20
EP0969859A1 (en) 2000-01-12
NO994622D0 (en) 1999-09-23
CN1251043A (en) 2000-04-19
NZ337985A (en) 2001-02-23
PL335829A1 (en) 2000-05-22
US6255283B1 (en) 2001-07-03
KR20010005705A (en) 2001-01-15
ITMI970694A1 (en) 1998-09-25
JP2001518107A (en) 2001-10-09

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