HUE061008T2 - Policiklusos aromás amin radioizotóppal jelzett kvaterner ammóniumsója, a radioaktív izotóppal jelzett vegyület használata pozitronemissziós tomográfia (pet) diagnosztikai eljárásban, valamint a policiklusos aromás amin radioaktív izotóppal jelzett kvaterner ammóniumsó vegyületét tartalmazó gyógyszerészeti készítmény - Google Patents

Policiklusos aromás amin radioizotóppal jelzett kvaterner ammóniumsója, a radioaktív izotóppal jelzett vegyület használata pozitronemissziós tomográfia (pet) diagnosztikai eljárásban, valamint a policiklusos aromás amin radioaktív izotóppal jelzett kvaterner ammóniumsó vegyületét tartalmazó gyógyszerészeti készítmény

Info

Publication number
HUE061008T2
HUE061008T2 HUE19786404A HUE19786404A HUE061008T2 HU E061008 T2 HUE061008 T2 HU E061008T2 HU E19786404 A HUE19786404 A HU E19786404A HU E19786404 A HUE19786404 A HU E19786404A HU E061008 T2 HUE061008 T2 HU E061008T2
Authority
HU
Hungary
Prior art keywords
radiolabelled compound
quaternary ammonium
ammonium salt
aromatic amine
polycyclic aromatic
Prior art date
Application number
HUE19786404A
Other languages
English (en)
Inventor
Joanna Towpik
Seweryn Krajewski
Lukasz Steczek
Joanna Wlostowska
Original Assignee
Synektik S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synektik S A filed Critical Synektik S A
Publication of HUE061008T2 publication Critical patent/HUE061008T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/041Heterocyclic compounds
    • A61K51/044Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D219/00Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/002Heterocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/227Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D219/00Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/02Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with only hydrogen, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D219/00Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/06Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • C07D221/06Ring systems of three rings
    • C07D221/10Aza-phenanthrenes
    • C07D221/12Phenanthridines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05Isotopically modified compounds, e.g. labelled

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HUE19786404A 2018-09-05 2019-09-04 Policiklusos aromás amin radioizotóppal jelzett kvaterner ammóniumsója, a radioaktív izotóppal jelzett vegyület használata pozitronemissziós tomográfia (pet) diagnosztikai eljárásban, valamint a policiklusos aromás amin radioaktív izotóppal jelzett kvaterner ammóniumsó vegyületét tartalmazó gyógyszerészeti készítmény HUE061008T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL426916A PL239871B1 (pl) 2018-09-05 2018-09-05 Znakowany radioizotopem związek czwartorzędowej soli amoniowej wielopierścieniowej aminy aromatycznej, zastosowanie znakowanego radioizotopem związku w metodzie diagnostycznej pozytonowej tomografii emisyjnej, a także kompozycja farmaceutyczna zawierająca znakowany radioizotopem związek czwartorzędowej soli amoniowej wielopierścieniowej aminy aromatycznej

Publications (1)

Publication Number Publication Date
HUE061008T2 true HUE061008T2 (hu) 2023-06-28

Family

ID=68208328

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE19786404A HUE061008T2 (hu) 2018-09-05 2019-09-04 Policiklusos aromás amin radioizotóppal jelzett kvaterner ammóniumsója, a radioaktív izotóppal jelzett vegyület használata pozitronemissziós tomográfia (pet) diagnosztikai eljárásban, valamint a policiklusos aromás amin radioaktív izotóppal jelzett kvaterner ammóniumsó vegyületét tartalmazó gyógyszerészeti készítmény

Country Status (9)

Country Link
US (1) US20210338847A1 (hu)
EP (1) EP3814325B1 (hu)
JP (1) JP7438197B2 (hu)
DK (1) DK3814325T3 (hu)
ES (1) ES2938415T3 (hu)
FI (1) FI3814325T3 (hu)
HU (1) HUE061008T2 (hu)
PL (1) PL239871B1 (hu)
WO (1) WO2020050729A1 (hu)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4062849A (en) 1968-05-02 1977-12-13 Produits Chimiques Ugine Kuhlmann Perfluoroalkylene quaternary heterocyclic nitrogen salts
US8524193B2 (en) * 2002-02-06 2013-09-03 The Johns Hopkins University Non-invasive diagnostic imaging technology for mitochondria using radiolabeled lipophilic salts
WO2011084585A2 (en) 2009-12-16 2011-07-14 Washington University Dihydroethidine analogues and uses thereof
WO2018207193A1 (en) * 2017-05-11 2018-11-15 Hadasit Medical Research Services And Development Ltd. Radiolabeled compounds that target organic cation transporters and uses thereof in radioimaging

Also Published As

Publication number Publication date
DK3814325T3 (da) 2023-01-30
FI3814325T3 (fi) 2023-03-01
EP3814325A1 (en) 2021-05-05
ES2938415T3 (es) 2023-04-10
EP3814325B1 (en) 2022-11-30
WO2020050729A1 (en) 2020-03-12
JP2021536495A (ja) 2021-12-27
JP7438197B2 (ja) 2024-02-26
PL426916A1 (pl) 2020-03-09
US20210338847A1 (en) 2021-11-04
PL239871B1 (pl) 2022-01-24

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