HUE043759T2 - Aurora a kinase inhibitor - Google Patents

Aurora a kinase inhibitor

Info

Publication number
HUE043759T2
HUE043759T2 HUE15798602A HUE15798602A HUE043759T2 HU E043759 T2 HUE043759 T2 HU E043759T2 HU E15798602 A HUE15798602 A HU E15798602A HU E15798602 A HUE15798602 A HU E15798602A HU E043759 T2 HUE043759 T2 HU E043759T2
Authority
HU
Hungary
Prior art keywords
aurora
kinase inhibitor
kinase
inhibitor
Prior art date
Application number
HUE15798602A
Other languages
Hungarian (hu)
Inventor
James Robert Henry
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HUE043759T2 publication Critical patent/HUE043759T2/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
HUE15798602A 2014-11-14 2015-11-06 Aurora a kinase inhibitor HUE043759T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462079742P 2014-11-14 2014-11-14

Publications (1)

Publication Number Publication Date
HUE043759T2 true HUE043759T2 (en) 2019-09-30

Family

ID=54697647

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE18204389A HUE051530T2 (en) 2014-11-14 2015-11-06 Aurora a kinase inhibitor
HUE15798602A HUE043759T2 (en) 2014-11-14 2015-11-06 Aurora a kinase inhibitor

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HUE18204389A HUE051530T2 (en) 2014-11-14 2015-11-06 Aurora a kinase inhibitor

Country Status (41)

Country Link
US (2) US9637474B2 (en)
EP (2) EP3218366B1 (en)
JP (1) JP6159029B2 (en)
KR (1) KR101930182B1 (en)
CN (1) CN107108567B (en)
AR (1) AR102463A1 (en)
AU (1) AU2015347043B2 (en)
BR (1) BR112017007239B1 (en)
CA (1) CA2963473C (en)
CL (1) CL2017001209A1 (en)
CO (1) CO2017004784A2 (en)
CR (1) CR20170158A (en)
CY (2) CY1121334T1 (en)
DK (2) DK3473619T3 (en)
DO (1) DOP2017000111A (en)
EA (1) EA032102B1 (en)
EC (1) ECSP17029203A (en)
ES (2) ES2826448T3 (en)
HR (2) HRP20190324T1 (en)
HU (2) HUE051530T2 (en)
IL (1) IL251406B (en)
JO (1) JO3488B1 (en)
LT (2) LT3218366T (en)
ME (1) ME03325B (en)
MX (1) MX2017006275A (en)
MY (1) MY188313A (en)
NZ (1) NZ730771A (en)
PE (1) PE20170898A1 (en)
PH (1) PH12017500881B1 (en)
PL (1) PL3218366T3 (en)
PT (2) PT3218366T (en)
RS (2) RS58347B1 (en)
SG (1) SG11201703394RA (en)
SI (2) SI3218366T1 (en)
SV (1) SV2017005418A (en)
TN (1) TN2017000116A1 (en)
TR (1) TR201902686T4 (en)
TW (1) TWI693218B (en)
UA (1) UA117983C2 (en)
WO (1) WO2016077161A1 (en)
ZA (1) ZA201702199B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7227968B2 (en) * 2018-05-29 2023-02-22 大鵬薬品工業株式会社 Antitumor agent and tumor treatment method
CN113038950A (en) 2018-11-30 2021-06-25 伊莱利利公司 Aurora A kinase inhibitors for the treatment of neuroblastoma
CN112239465A (en) * 2019-07-16 2021-01-19 微境生物医药科技(上海)有限公司 Aurora kinase inhibitor and use thereof
CN112898292A (en) * 2019-12-03 2021-06-04 微境生物医药科技(上海)有限公司 Novel aurora kinase inhibitor and use thereof
TWI785474B (en) 2020-01-22 2022-12-01 大陸商北京加科思新藥研發有限公司 Novel heterocyclic compounds useful as selective aurora a inhibitors
KR20240012437A (en) 2021-05-24 2024-01-29 지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 Nitrogen-containing heterocyclic compounds, methods for their preparation and their applications in medicine
AR126581A1 (en) * 2021-07-28 2023-10-25 Jacobio Pharmaceuticals Co Ltd POLYMORPHIC FORMS OF SELECTIVE AURORA A INHIBITORS AND USES THEREOF
WO2023196887A1 (en) 2022-04-08 2023-10-12 Eli Lilly And Company Method of treatment including kras g12c inhibitors and aurora a inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006008874A1 (en) * 2004-05-21 2006-01-26 Banyu Pharmaceutical Co., Ltd. SELECTIVE INHIBITORS AGAINST Cdk4 AND Cdk6 HAVING AMINOTHIAZOLE SKELETON
NZ554441A (en) * 2004-10-29 2009-07-31 Banyu Pharma Co Ltd Novel aminopyridine derivatives having aurora A selective inhibitory action
JP2008081492A (en) 2006-08-31 2008-04-10 Banyu Pharmaceut Co Ltd New aminopyridine derivative having aurora a selective inhibitory action
ES2531398T3 (en) * 2008-02-22 2015-03-13 Msd Kk New aminopyridine derivatives that have a selective inhibitory action on Aurora A
KR20120004467A (en) * 2009-03-24 2012-01-12 엠에스디 가부시키가이샤 Novel aminopyridine derivatives having aurora a selective inhibitory action
TWI485146B (en) * 2012-02-29 2015-05-21 Taiho Pharmaceutical Co Ltd Novel piperidine compounds or salts thereof

Also Published As

Publication number Publication date
EP3218366B1 (en) 2019-01-09
EP3473619B1 (en) 2020-09-09
HUE051530T2 (en) 2021-03-01
LT3473619T (en) 2020-11-10
RS58347B1 (en) 2019-03-29
SG11201703394RA (en) 2017-05-30
EA201790838A1 (en) 2017-12-29
DOP2017000111A (en) 2017-06-15
ES2716732T3 (en) 2019-06-14
US10010540B2 (en) 2018-07-03
TN2017000116A1 (en) 2018-07-04
CA2963473C (en) 2018-12-18
ES2826448T3 (en) 2021-05-18
AU2015347043A1 (en) 2017-05-04
EP3473619A1 (en) 2019-04-24
MX2017006275A (en) 2017-08-14
RS60999B1 (en) 2020-11-30
JO3488B1 (en) 2020-07-05
CY1121334T1 (en) 2020-05-29
SI3218366T1 (en) 2019-02-28
US20170119751A1 (en) 2017-05-04
DK3218366T3 (en) 2019-04-01
IL251406B (en) 2019-08-29
EA032102B1 (en) 2019-04-30
CR20170158A (en) 2017-06-21
AU2015347043B2 (en) 2018-03-22
PH12017500881A1 (en) 2017-11-06
HRP20201681T1 (en) 2020-12-25
CN107108567B (en) 2020-01-10
ECSP17029203A (en) 2018-01-31
WO2016077161A1 (en) 2016-05-19
PE20170898A1 (en) 2017-07-12
DK3473619T3 (en) 2020-09-21
SV2017005418A (en) 2018-10-09
TR201902686T4 (en) 2019-03-21
JP2016539942A (en) 2016-12-22
NZ730771A (en) 2018-07-27
TWI693218B (en) 2020-05-11
CL2017001209A1 (en) 2018-01-12
PL3218366T3 (en) 2019-06-28
US20160137628A1 (en) 2016-05-19
CA2963473A1 (en) 2016-05-19
BR112017007239A2 (en) 2017-12-19
MY188313A (en) 2021-11-27
KR101930182B1 (en) 2018-12-17
ME03325B (en) 2019-10-20
CN107108567A (en) 2017-08-29
JP6159029B2 (en) 2017-07-05
BR112017007239B1 (en) 2023-01-31
HRP20190324T1 (en) 2019-04-19
UA117983C2 (en) 2018-10-25
PH12017500881B1 (en) 2017-11-06
AR102463A1 (en) 2017-03-01
PT3218366T (en) 2019-04-01
CO2017004784A2 (en) 2017-08-31
EP3473619B8 (en) 2020-11-04
US9637474B2 (en) 2017-05-02
EP3218366A1 (en) 2017-09-20
KR20170066623A (en) 2017-06-14
CY1123592T1 (en) 2022-03-24
LT3218366T (en) 2019-04-10
ZA201702199B (en) 2018-12-19
PT3473619T (en) 2020-11-11
TW201629038A (en) 2016-08-16
SI3473619T1 (en) 2020-10-30
IL251406A0 (en) 2017-05-29

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