HU9203032D0 - An improved process for expression of recombinant polypeptides of small molecular mass - Google Patents
An improved process for expression of recombinant polypeptides of small molecular massInfo
- Publication number
- HU9203032D0 HU9203032D0 HU9203032A HU9203032A HU9203032D0 HU 9203032 D0 HU9203032 D0 HU 9203032D0 HU 9203032 A HU9203032 A HU 9203032A HU 9203032 A HU9203032 A HU 9203032A HU 9203032 D0 HU9203032 D0 HU 9203032D0
- Authority
- HU
- Hungary
- Prior art keywords
- expression
- molecular mass
- improved process
- small molecular
- recombinant polypeptides
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Diabetes (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/764,655 US5378613A (en) | 1991-09-24 | 1991-09-24 | Method for increased expression of low molecular weight recombinant polypeptides |
Publications (2)
Publication Number | Publication Date |
---|---|
HU9203032D0 true HU9203032D0 (en) | 1992-11-30 |
HUT62659A HUT62659A (en) | 1993-05-28 |
Family
ID=25071354
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9203032A HUT62659A (en) | 1991-09-24 | 1992-09-23 | Process for the increased expression of recombinant polypeptides of small molecular weight |
Country Status (8)
Country | Link |
---|---|
US (1) | US5378613A (hu) |
EP (1) | EP0534705A3 (hu) |
JP (1) | JPH05304978A (hu) |
AU (1) | AU655316B2 (hu) |
CA (1) | CA2079027A1 (hu) |
HU (1) | HUT62659A (hu) |
IL (1) | IL103203A0 (hu) |
MX (1) | MX9205312A (hu) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3406244B2 (ja) * | 1999-04-30 | 2003-05-12 | 伊藤ハム株式会社 | 新規な融合蛋白質からの組み換えインスリンの製造方法 |
EP1183357A2 (en) * | 1999-05-20 | 2002-03-06 | Scios Inc. | Vascular endothelial growth factor dimers |
JP2003507006A (ja) * | 1999-05-20 | 2003-02-25 | サイオス,インコーポレーテッド | 血管内皮増殖因子改変体 |
US6689747B2 (en) | 2000-03-24 | 2004-02-10 | Genentech, Inc. | Use of insulin for the treatment of cartilagenous disorders |
WO2002051238A2 (en) * | 2000-12-26 | 2002-07-04 | Monsanto Technology Llc | Recombinant dna vectors for expression of somatotropins |
WO2012048856A1 (en) * | 2010-10-12 | 2012-04-19 | Glucometrix Pvs Gmbh | Proinsulin with helper sequence |
WO2013149729A2 (en) * | 2012-04-04 | 2013-10-10 | Glucometrix Ag | Proinsulin with enhanced helper sequence |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4782139A (en) * | 1985-10-28 | 1988-11-01 | Eli Lilly And Company | Selective chemical removal of a protein amino-terminal residue |
JPH03503596A (ja) * | 1987-06-24 | 1991-08-15 | ノボ・ノルディスク エー/エス | 蛋白質若しくはポリペプチドの調製方法、該ポリペプチドをコードするdna配列、該dna配列およびポリペプチドを有する微生物および該ポリペプチドの薬学的製剤としての利用 |
DK470689A (da) * | 1988-09-30 | 1990-03-31 | Lilly Co Eli | Hidtil ukendte dna-sekvenser, der koder for protein-derivater, som tillader hoej udtrykkelse af rekombinante proteiner med ringe molekylevaegt |
US5158875A (en) * | 1989-08-25 | 1992-10-27 | Amgen Inc. | Production of biologically active insulin-like growth factor i from high expression host cell systems |
US5304473A (en) * | 1991-06-11 | 1994-04-19 | Eli Lilly And Company | A-C-B proinsulin, method of manufacturing and using same, and intermediates in insulin production |
-
1991
- 1991-09-24 US US07/764,655 patent/US5378613A/en not_active Expired - Fee Related
-
1992
- 1992-09-17 IL IL103203A patent/IL103203A0/xx unknown
- 1992-09-18 MX MX9205312A patent/MX9205312A/es unknown
- 1992-09-22 EP EP92308601A patent/EP0534705A3/en not_active Withdrawn
- 1992-09-22 JP JP4252727A patent/JPH05304978A/ja not_active Withdrawn
- 1992-09-22 AU AU25280/92A patent/AU655316B2/en not_active Ceased
- 1992-09-23 HU HU9203032A patent/HUT62659A/hu unknown
- 1992-09-24 CA CA002079027A patent/CA2079027A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP0534705A2 (en) | 1993-03-31 |
MX9205312A (es) | 1993-07-01 |
US5378613A (en) | 1995-01-03 |
AU2528092A (en) | 1993-03-25 |
JPH05304978A (ja) | 1993-11-19 |
AU655316B2 (en) | 1994-12-15 |
IL103203A0 (en) | 1993-02-21 |
EP0534705A3 (en) | 1994-12-14 |
HUT62659A (en) | 1993-05-28 |
CA2079027A1 (en) | 1993-03-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
DFD9 | Temporary protection cancelled due to non-payment of fee |