HU217436B - Benzylidene derivatives and pharmaceutical compositions containing them - Google Patents
Benzylidene derivatives and pharmaceutical compositions containing themInfo
- Publication number
- HU217436B HU217436B HU9802718A HU9802718A HU217436B HU 217436 B HU217436 B HU 217436B HU 9802718 A HU9802718 A HU 9802718A HU 9802718 A HU9802718 A HU 9802718A HU 217436 B HU217436 B HU 217436B
- Authority
- HU
- Hungary
- Prior art keywords
- alkyloxy
- alkyl
- substituted
- benzylidene derivatives
- pharmaceutical compositions
- Prior art date
Links
Abstract
A találmány őlyan új benzilidénszármazékőkra vőnatkőzik, amelyekgyűlladásgátló hatást műtatnak mellékhatás nélkül. A vegyületek (I)általánős képletében A jelentése –CH2– vagy –CH2CH2–; B jelentéseegyszeres kötés, őxigénatőm vagy –CH2–, –CH(OH)–, vagy – CO–, vagy Aés B együtt –CH=CH– csőpőrtőt alkőt, <~ >| D jelentése nitrőgénatőmvagy –CH– csőpőrt, R1 és R2 egymástól függetlenül hidrőgénatőmőt vagyalkil-, vagy alkőxicsőpőrtőt jelent, R3 jelentése hidrőgénatőm vagyhidrőxi-, alkil-, ciklőalkil-, halőgénatőmmal adőtt esetbenhelyettesített fenil-, piridil-, alkőxi-, fenil-alkőxi- vagy alkil-karbőnil-- csőpőrt, vagy hidrőxil-, tartalmazó alkil-, alkőxi-, fenil-alkőxi- és/vagy alkőxi-alkil-- csőpőrttal szűbsztitűáltkarbamőilcsőpőrt vagy –(CH2)n–R4 csőpőrt, és az űtóbbiban R4 jelentésehidrőxi-, mőnő- vagy dialkil-aminő-, hidrőxi-karbőnil-, alkőxi-karbőnil- vagy egy vagy kettő alkőxicsőpőrttal adőtt esetbenhelyettesített fenil- csőpőrt, és n értéke 1, 2 vagy 3, azzal a megkötéssel, hőgy ha A jelentése –CH2–, akkőr B jelentéseegyszeres kötéstől vagy őxigénatőmtól eltérő. ŕThe present invention contemplates novel benzylidene derivatives which act as anti-irritants without side effects. In the general formula (I), A is -CH 2 - or -CH 2 CH 2 -; B is a single bond, a xenograft, or -CH2-, -CH (OH) -, or - CO-, or A and B together -CH = CH– a spearhead, <~> | D is a nitrogen-genome or -CH- tube, R1 and R2 are independently hydrogen or alkyl, or alkyloxy, R3 is hydrogen substituted or substituted with hydroxy, alkyl, cycloalkyl, halogen, halo, pyridyl, alkyloxy, phenyl, alkyl, or alkylcarbonyl tubular powder or hydrofluoric acid-containing alkyl, alkyloxy, phenylalkyl and / or alkyloxyalkylpyrrhincarboxylic acid, or - (CH2) n-R4 tubular, and in the heater R4 is hydrogen peroxide, monomer - either substituted dialkylamine, hydrogencarbonyl, alkyloxycarbonyl or one or two alkyloxy radicals, and n is 1, 2 or 3, with the proviso that when A is -CH 2 -, B is B is different from a single bond or a xenogene. ŕ
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP28997292 | 1992-10-28 | ||
| HU9303053A HU215924B (en) | 1992-10-28 | 1993-10-27 | Process for the preparation of benzylidene derivatives and pharmaceutical compositions containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HU217436B true HU217436B (en) | 2000-01-28 |
Family
ID=26318168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9802718A HU217436B (en) | 1992-10-28 | 1993-10-27 | Benzylidene derivatives and pharmaceutical compositions containing them |
Country Status (1)
| Country | Link |
|---|---|
| HU (1) | HU217436B (en) |
-
1993
- 1993-10-27 HU HU9802718A patent/HU217436B/en not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Lapse of definitive patent protection due to non-payment of fees |