HU214194B - Process for the preparation of n--dichloracetyl-1-oxa-4-azaspiro-(4,5)-decane - Google Patents
Process for the preparation of n--dichloracetyl-1-oxa-4-azaspiro-(4,5)-decaneInfo
- Publication number
- HU214194B HU214194B HU9403302A HU9403302A HU214194B HU 214194 B HU214194 B HU 214194B HU 9403302 A HU9403302 A HU 9403302A HU 9403302 A HU9403302 A HU 9403302A HU 214194 B HU214194 B HU 214194B
- Authority
- HU
- Hungary
- Prior art keywords
- oxa
- decane
- dichloroacetyl
- aza
- spiro
- Prior art date
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
A találmány tárgya eljárás N-(diklór-acetil)-1-őxa-4- -aza-spirő[4,5]dekán előállítására őldószeres közegben, mőnő-etanől-amin, ciklőhexanőn és diklór-acetil-klőrid 1:1:(1–1,2) mólaránybantörténő reagáltatásával savmegkötő szer jelenlétében őly m dőn, hőgyaz N- -(diklór-acetil)-1-őxa-4-aza-spirő[4,5]dekán előállítását egylépésben, a kiindűlási anyagők 20 řC alatti hőmérsékleten 7–14 pH-értéken történő reagáltatásával őldószerként telített alifás és/v gyciklőalifás szénhidrőgént alkalmazva végzik, majd a reakcióelegyből azN-(diklór-acetil)-1-őxa-4-aza-spirő[4,5]dekánt ismert módőn kinyerik. ŕThe present invention relates to a process for the preparation of N- (dichloroacetyl) -1-oxa-4-aza-spiro [4,5] decane in a brewing medium, from 1: 1 ethanolic amine, cyclohexane and dichloroacetyl chlorine. 1-1.2) reacting in molar ratio in the presence of an acid scavenger in the same manner, producing a thermoplastic N- (dichloroacetyl) -1-oxa-4-aza-spiro [4,5] decane in a single step at a temperature below 20 20C. Reaction at pH 7-14 is carried out using saturated aliphatic and / or cyclic aliphatic hydrocarbon as the cooling agent, and then the N- (dichloroacetyl) -1-oxa-4-aza-spiro [4,5] decane is recovered in a known manner. ŕ
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU9403302A HU214194B (en) | 1994-11-18 | 1994-11-18 | Process for the preparation of n--dichloracetyl-1-oxa-4-azaspiro-(4,5)-decane |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU9403302A HU214194B (en) | 1994-11-18 | 1994-11-18 | Process for the preparation of n--dichloracetyl-1-oxa-4-azaspiro-(4,5)-decane |
Publications (2)
Publication Number | Publication Date |
---|---|
HU9403302D0 HU9403302D0 (en) | 1995-01-30 |
HU214194B true HU214194B (en) | 1998-04-28 |
Family
ID=10985767
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9403302A HU214194B (en) | 1994-11-18 | 1994-11-18 | Process for the preparation of n--dichloracetyl-1-oxa-4-azaspiro-(4,5)-decane |
Country Status (1)
Country | Link |
---|---|
HU (1) | HU214194B (en) |
-
1994
- 1994-11-18 HU HU9403302A patent/HU214194B/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HU9403302D0 (en) | 1995-01-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0582790T3 (en) | New Process for Preparation of 7-Substituted-9 - [(Substituted Glycyl) Amino] -6-Demethyl-6-Deoxytetracyclines | |
DE3680800D1 (en) | METHOD FOR PRODUCING (6R) -TETRAHYDRO-L-BIOPTERIN. | |
IL116281A0 (en) | Process for the purification of(rr-ss)-2- dimethyl-aminomethyl-1-(3-methoxyphenyl) cyclohexanol and its salts | |
MY113863A (en) | Method for preparing n, n' - disubstituted cyclic ureas | |
UA43341C2 (en) | Process for urea synthesis (variants) | |
HUT42287A (en) | Fungicides containing as active substance morfolinioalcane carbonic acid amid salts and process for production of the active substance | |
HU214194B (en) | Process for the preparation of n--dichloracetyl-1-oxa-4-azaspiro-(4,5)-decane | |
GB1435187A (en) | Normorphinone derivatives and pharmaceutical uses thereof | |
ATE68478T1 (en) | PROCESS FOR THE PRODUCTION OF 1,6-DI(N3-CYANO-N1-GUANIDINO)HEXANE. | |
NO20012492L (en) | Process for the preparation of N-alkyl-N'-nitroguanidine | |
DE69031623D1 (en) | THIOACYLATING AGENTS AND INTERMEDIATE PRODUCTS, THIOPEPTIDES, AND METHOD FOR THE PRODUCTION AND USE THEREOF | |
ATE69800T1 (en) | PROCESSES FOR THE PRODUCTION OF AMINES. | |
NO20010121L (en) | Process for Preparation of (1R, 4S) -2-Azabicyclo [2.2.1] Hept-5-En-3-One Derivatives | |
MY122033A (en) | Process for the preparation of a mixture of e-caprolactam, 6-aminocaproic acid and 6-aminocaproic amide | |
RU94045250A (en) | Processes for preparing 2-perfluoroalkyl-3-oxazoline-5- one intermediate compounds | |
Tsunoda et al. | An efficient method for hydrolysis of N-monosubstituted amides via acetoxypivalimides | |
ATE236875T1 (en) | METHOD FOR PRODUCING CYCLIC LACTAMS | |
HK1027560A1 (en) | Method for producing 1,3-disubstituted 2-nitroguanidines | |
ATE45727T1 (en) | PROCESS FOR THE PREPARATION OF N-SUBSTITUTED, ALPHA, BETA-UNSATURATED CARBONIC AMIDES. | |
JPS5686184A (en) | Novel mitomycin c derivative | |
JPS55122750A (en) | Production of aminonitrile | |
WO2000009509A3 (en) | Process for the large-scale synthesis of 4,10-dinitro -2,6,8,12- tetraoxa- 4,10-diazatetracyclo- [5.5.0.0?5,903,11¿]- dodecane | |
TH2473B (en) | 2 - Alkoxi aminosulfonyl-benzene-sulfonylurea, a new type of herbicide. | |
GB1358700A (en) | Method of producing a tetrachlorinated cyclic ketone | |
SU1732666A1 (en) | Thiophosphorylated lactam oximes showing insecto-acaricidic activity |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
HPC4 | Succession in title of patentee |
Owner name: NITROKEMIA 2000 IPARI ES VAGYONKEZELOE RT., HU |
|
MM4A | Lapse of definitive patent protection due to non-payment of fees | ||
GB9A | Succession in title |
Owner name: AGAN CHEMICAL MANUFACTURERS LTD., IL Free format text: FORMER OWNER(S): NITROKEMIA 2000 IPARI ES VAGYONKEZELOE RT., HU; NITROKEMIA RT., HU |
|
NF4A | Restoration of patent protection | ||
MM4A | Lapse of definitive patent protection due to non-payment of fees |