HU0301154D0 - Pharmaceutical composition - Google Patents
Pharmaceutical compositionInfo
- Publication number
- HU0301154D0 HU0301154D0 HU0301154A HUP0301154A HU0301154D0 HU 0301154 D0 HU0301154 D0 HU 0301154D0 HU 0301154 A HU0301154 A HU 0301154A HU P0301154 A HUP0301154 A HU P0301154A HU 0301154 D0 HU0301154 D0 HU 0301154D0
- Authority
- HU
- Hungary
- Prior art keywords
- pharmaceutical composition
- pharmaceutical
- composition
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU0301154A HU0301154D0 (en) | 2003-04-28 | 2003-04-28 | Pharmaceutical composition |
US10/553,937 US20070072912A1 (en) | 2003-04-28 | 2004-04-27 | Alicyclic-amine-substituted 4-carboxamido-benzimidazoles as parp-inhibitors and antioxidants |
PCT/HU2004/000043 WO2004096793A1 (en) | 2003-04-28 | 2004-04-27 | New alicyclic-amine-substituted 4-carboxamido-benzimidazoles as parp-inhibitors and antioxidants |
EP04729685A EP1622893A1 (en) | 2003-04-28 | 2004-04-27 | New alicyclic-amine-substituted 4-carboxamido-benzimidazoles as parp-inhibitors and antioxidants |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU0301154A HU0301154D0 (en) | 2003-04-28 | 2003-04-28 | Pharmaceutical composition |
Publications (1)
Publication Number | Publication Date |
---|---|
HU0301154D0 true HU0301154D0 (en) | 2003-07-28 |
Family
ID=89981334
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0301154A HU0301154D0 (en) | 2003-04-28 | 2003-04-28 | Pharmaceutical composition |
Country Status (4)
Country | Link |
---|---|
US (1) | US20070072912A1 (hu) |
EP (1) | EP1622893A1 (hu) |
HU (1) | HU0301154D0 (hu) |
WO (1) | WO2004096793A1 (hu) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102005012874A1 (de) * | 2005-03-19 | 2006-09-21 | Sanofi-Aventis Deutschland Gmbh | Amid substituierte 8-N-Benzimidazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
WO2006110683A1 (en) | 2005-04-11 | 2006-10-19 | Abbott Laboratories | 2-substituted-1h-benzimidazole-4-carboxamides are parp inhibitors |
TWI375673B (en) | 2005-04-11 | 2012-11-01 | Abbott Lab | 1h-benzimidazole-4-carboxamides substituted with a quaternary carbon at the 2-position are potent parp inhibitors |
ATE536349T1 (de) * | 2005-09-29 | 2011-12-15 | Abbott Lab | In der 2-stellung durch phenyl substituierte 1h- benzimidazol-4-carbonsäureamide sind wirksame parp-inhibitoren |
CN101309908A (zh) | 2005-11-15 | 2008-11-19 | 艾博特公司 | 作为有效parp抑制剂的取代的1h-苯并咪唑-4-甲酰胺化合物 |
EP2012780B1 (en) | 2006-05-02 | 2012-04-11 | Abbott Laboratories | Substituted 1h-benzimidazole-4-carboxamides are potent parp inhibitors |
GEP20115337B (en) | 2007-01-10 | 2011-11-25 | St Di Ricerche Di Biologia Molecolare P Angeletti Spa | Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors |
EP2620429A1 (en) * | 2007-02-22 | 2013-07-31 | Colby Pharmaceutical Company | Hydroxylamine compounds and methods of their use |
US8067613B2 (en) | 2007-07-16 | 2011-11-29 | Abbott Laboratories | Benzimidazole poly(ADP ribose)polymerase inhibitors |
US20090062268A1 (en) * | 2007-08-27 | 2009-03-05 | Lead Therapeutics, Inc. | Novel inhibitors of poly(adp-ribose)polymerase (parp) |
KR101039752B1 (ko) | 2008-08-20 | 2011-06-09 | 한국화학연구원 | 2-벤질설파닐-벤즈이미다졸-4-카르복스아미드 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 폴리(adp-리보스)폴리머라제-1(parp-1)의 과활성에 의해 유발되는 질환의 예방 또는 치료용 약학적 조성물 |
KR101007239B1 (ko) | 2008-08-20 | 2011-01-13 | 한국화학연구원 | 2-설파닐-벤즈이미다졸-4-카르복스아미드 유도체 또는 이의약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 폴리(adp-리보스)폴리머라제-1(parp-1)의 과활성에 의해 유발되는 질환의 예방 또는 치료용 약학적 조성물 |
KR101089713B1 (ko) | 2008-08-20 | 2011-12-07 | 한국화학연구원 | 2-(2-옥소-2-페닐에틸설파닐)-벤즈이미다졸-4-카르복스아미드 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 폴리(adp-리보스)폴리머라제-1(parp-1)의 과활성에 의해 유발되는 질환의 예방 또는 치료용 약학적 조성물 |
WO2010081488A1 (en) * | 2009-01-15 | 2010-07-22 | Humanitas Mirasole S.P.A. | Nitric oxide furoxan derivative compounds endowed with antitumoral activity |
WO2010083199A1 (en) | 2009-01-19 | 2010-07-22 | Abbott Laboratories | Benzthiazole inhibitors of poly(adp-ribose)polymerase |
NZ595819A (en) * | 2009-04-02 | 2013-02-22 | Merck Serono Sa | DIHYDROOROTATE DEHYDROGENASE INHIBITORS; benzimidazole-4-carboxylic acid |
US8722707B1 (en) | 2009-07-06 | 2014-05-13 | The Ohio State University | Compositions and methods for inhibition of smooth muscle cell proliferation and neointimal hyperplasia |
WO2011058367A2 (en) | 2009-11-13 | 2011-05-19 | Astrazeneca Ab | Diagnostic test for predicting responsiveness to treatment with poly(adp-ribose) polymerase (parp) inhibitor |
US8795850B2 (en) * | 2011-05-19 | 2014-08-05 | Universal Display Corporation | Phosphorescent heteroleptic phenylbenzimidazole dopants and new synthetic methodology |
ES2700348T3 (es) * | 2014-01-05 | 2019-02-15 | Univ Washington | Trazadores radioetiquetados para poli (ADP-ribosa) polimerasa-1 (PARP-1), métodos y usos para estos |
CN106317069A (zh) * | 2015-06-26 | 2017-01-11 | 中国科学院上海药物研究所 | 2-取代苯并咪唑-4-甲酰胺类化合物及制备方法和应用 |
GB201519573D0 (en) | 2015-11-05 | 2015-12-23 | King S College London | Combination |
EP3615026B1 (en) | 2017-04-28 | 2021-03-03 | Akribes Biomedical GmbH | A parp inhibitor in combination with a glucocorticoid and/or ascorbic acid and/or a protein growth factor for the treatment of impaired wound healing |
WO2019175132A1 (en) | 2018-03-13 | 2019-09-19 | Onxeo | A dbait molecule against acquired resistance in the treatment of cancer |
WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUP0200749A3 (en) * | 1998-11-27 | 2003-03-28 | Basf Ag | Substituted benzimidazoles and their use as parp inhibitors and process for their preparation |
WO2001021615A1 (en) * | 1999-09-17 | 2001-03-29 | Yamanouchi Pharmaceutical Co., Ltd. | Benzimidazole derivatives |
-
2003
- 2003-04-28 HU HU0301154A patent/HU0301154D0/hu unknown
-
2004
- 2004-04-27 US US10/553,937 patent/US20070072912A1/en not_active Abandoned
- 2004-04-27 EP EP04729685A patent/EP1622893A1/en not_active Withdrawn
- 2004-04-27 WO PCT/HU2004/000043 patent/WO2004096793A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2004096793A1 (en) | 2004-11-11 |
EP1622893A1 (en) | 2006-02-08 |
US20070072912A1 (en) | 2007-03-29 |
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