HU0301154D0 - Pharmaceutical composition - Google Patents

Pharmaceutical composition

Info

Publication number
HU0301154D0
HU0301154D0 HU0301154A HUP0301154A HU0301154D0 HU 0301154 D0 HU0301154 D0 HU 0301154D0 HU 0301154 A HU0301154 A HU 0301154A HU P0301154 A HUP0301154 A HU P0301154A HU 0301154 D0 HU0301154 D0 HU 0301154D0
Authority
HU
Hungary
Prior art keywords
pharmaceutical composition
pharmaceutical
composition
Prior art date
Application number
HU0301154A
Other languages
English (en)
Original Assignee
Hideg Kalman Dr
Suemegi Balazs Dr
Kalai Tamas Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hideg Kalman Dr, Suemegi Balazs Dr, Kalai Tamas Dr filed Critical Hideg Kalman Dr
Priority to HU0301154A priority Critical patent/HU0301154D0/hu
Publication of HU0301154D0 publication Critical patent/HU0301154D0/hu
Priority to EP04729685A priority patent/EP1622893A1/en
Priority to PCT/HU2004/000043 priority patent/WO2004096793A1/en
Priority to US10/553,937 priority patent/US20070072912A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
HU0301154A 2003-04-28 2003-04-28 Pharmaceutical composition HU0301154D0 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
HU0301154A HU0301154D0 (en) 2003-04-28 2003-04-28 Pharmaceutical composition
EP04729685A EP1622893A1 (en) 2003-04-28 2004-04-27 New alicyclic-amine-substituted 4-carboxamido-benzimidazoles as parp-inhibitors and antioxidants
PCT/HU2004/000043 WO2004096793A1 (en) 2003-04-28 2004-04-27 New alicyclic-amine-substituted 4-carboxamido-benzimidazoles as parp-inhibitors and antioxidants
US10/553,937 US20070072912A1 (en) 2003-04-28 2004-04-27 Alicyclic-amine-substituted 4-carboxamido-benzimidazoles as parp-inhibitors and antioxidants

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU0301154A HU0301154D0 (en) 2003-04-28 2003-04-28 Pharmaceutical composition

Publications (1)

Publication Number Publication Date
HU0301154D0 true HU0301154D0 (en) 2003-07-28

Family

ID=89981334

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0301154A HU0301154D0 (en) 2003-04-28 2003-04-28 Pharmaceutical composition

Country Status (4)

Country Link
US (1) US20070072912A1 (hu)
EP (1) EP1622893A1 (hu)
HU (1) HU0301154D0 (hu)
WO (1) WO2004096793A1 (hu)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005012874A1 (de) * 2005-03-19 2006-09-21 Sanofi-Aventis Deutschland Gmbh Amid substituierte 8-N-Benzimidazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
WO2006110683A1 (en) 2005-04-11 2006-10-19 Abbott Laboratories 2-substituted-1h-benzimidazole-4-carboxamides are parp inhibitors
TWI375673B (en) * 2005-04-11 2012-11-01 Abbott Lab 1h-benzimidazole-4-carboxamides substituted with a quaternary carbon at the 2-position are potent parp inhibitors
CN101316834A (zh) * 2005-09-29 2008-12-03 艾博特公司 在2位取代有苯基的1h-苯并咪唑-4-甲酰胺是强效parp抑制剂
JP5162465B2 (ja) 2005-11-15 2013-03-13 アボット・ラボラトリーズ 置換１ｈ−ベンズイミダゾール−４−カルボキサミド類は強力なｐａｒｐ阻害薬である
ATE553104T1 (de) 2006-05-02 2012-04-15 Abbott Lab Substituierte 1h-benzimidazol-4-carboxamide als potente parp-hemmer
DK2805945T3 (da) 2007-01-10 2019-07-15 Msd Italia Srl Amid-substituerede indazoler som poly(adp-ribose)polymerase- (parp) hæmmere
CA2679066A1 (en) * 2007-02-22 2008-08-28 Othera Holding, Inc. Hydroxylamine compounds and methods of their use
US8067613B2 (en) * 2007-07-16 2011-11-29 Abbott Laboratories Benzimidazole poly(ADP ribose)polymerase inhibitors
US20090062268A1 (en) * 2007-08-27 2009-03-05 Lead Therapeutics, Inc. Novel inhibitors of poly(adp-ribose)polymerase (parp)
KR101007239B1 (ko) 2008-08-20 2011-01-13 한국화학연구원 2-설파닐-벤즈이미다졸-4-카르복스아미드 유도체 또는 이의약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 폴리(ａｄｐ-리보스)폴리머라제-1(ｐａｒｐ-1)의 과활성에 의해 유발되는 질환의 예방 또는 치료용 약학적 조성물
KR101039752B1 (ko) 2008-08-20 2011-06-09 한국화학연구원 2-벤질설파닐-벤즈이미다졸-4-카르복스아미드 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 폴리(ａｄｐ-리보스)폴리머라제-1(ｐａｒｐ-1)의 과활성에 의해 유발되는 질환의 예방 또는 치료용 약학적 조성물
KR101089713B1 (ko) 2008-08-20 2011-12-07 한국화학연구원 2-(2-옥소-2-페닐에틸설파닐)-벤즈이미다졸-4-카르복스아미드 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 폴리(ａｄｐ-리보스)폴리머라제-1(ｐａｒｐ-1)의 과활성에 의해 유발되는 질환의 예방 또는 치료용 약학적 조성물
WO2010081488A1 (en) 2009-01-15 2010-07-22 Humanitas Mirasole S.P.A. Nitric oxide furoxan derivative compounds endowed with antitumoral activity
WO2010083199A1 (en) 2009-01-19 2010-07-22 Abbott Laboratories Benzthiazole inhibitors of poly(adp-ribose)polymerase
AU2010233917B2 (en) * 2009-04-02 2015-07-02 Merck Serono S.A. Dihydroorotate dehydrogenase inhibitors
US8722707B1 (en) 2009-07-06 2014-05-13 The Ohio State University Compositions and methods for inhibition of smooth muscle cell proliferation and neointimal hyperplasia
WO2011058367A2 (en) 2009-11-13 2011-05-19 Astrazeneca Ab Diagnostic test for predicting responsiveness to treatment with poly(adp-ribose) polymerase (parp) inhibitor
US8795850B2 (en) * 2011-05-19 2014-08-05 Universal Display Corporation Phosphorescent heteroleptic phenylbenzimidazole dopants and new synthetic methodology
CA2935857C (en) * 2014-01-05 2020-12-15 Washington University Radiolabeled tracers for poly (adp-ribose) polymerase-1 (parp-1), methods and uses therefor
CN106317069A (zh) * 2015-06-26 2017-01-11 中国科学院上海药物研究所 2-取代苯并咪唑-4-甲酰胺类化合物及制备方法和应用
GB201519573D0 (en) 2015-11-05 2015-12-23 King S College London Combination
EP3615026B1 (en) 2017-04-28 2021-03-03 Akribes Biomedical GmbH A parp inhibitor in combination with a glucocorticoid and/or ascorbic acid and/or a protein growth factor for the treatment of impaired wound healing
CN111819282A (zh) 2018-03-13 2020-10-23 欧恩科斯欧公司 对抗癌症治疗中获得性耐药性的Dbait分子
WO2021148581A1 (en) 2020-01-22 2021-07-29 Onxeo Novel dbait molecule and its use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2001117757A (ru) * 1998-11-27 2004-02-27 БАСФ Акциенгезельшафт (DE) Замещенные бензимидазолы и их применение в качестве ингибиторов поли(аденозиндифосфатрибоза)полимеразы
AU7314200A (en) * 1999-09-17 2001-04-24 Yamanouchi Pharmaceutical Co., Ltd. Benzimidazole derivatives

Also Published As

Publication number Publication date
WO2004096793A1 (en) 2004-11-11
US20070072912A1 (en) 2007-03-29
EP1622893A1 (en) 2006-02-08

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