HRPK931105B1 - Mesenchymal regeneration by the use of hypolipemics, esters of aryloxycarbonic acid derivatives in mucocutaneous diseases, neurological diseases, diseases of locomotor system, ocular diseases, mesenchymal tumors, viral diseases and against aging - Google Patents
Mesenchymal regeneration by the use of hypolipemics, esters of aryloxycarbonic acid derivatives in mucocutaneous diseases, neurological diseases, diseases of locomotor system, ocular diseases, mesenchymal tumors, viral diseases and against agingInfo
- Publication number
- HRPK931105B1 HRPK931105B1 HRP931105AA HRP931105A HRPK931105B1 HR PK931105 B1 HRPK931105 B1 HR PK931105B1 HR P931105A A HRP931105A A HR P931105AA HR P931105 A HRP931105 A HR P931105A HR PK931105 B1 HRPK931105 B1 HR PK931105B1
- Authority
- HR
- Croatia
- Prior art keywords
- diseases
- mesenchymal
- neurological
- hypolipemics
- regeneration
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title abstract 10
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 10
- 239000002253 acid Substances 0.000 title abstract 3
- 230000003137 locomotive effect Effects 0.000 title abstract 3
- 201000008806 mesenchymal cell neoplasm Diseases 0.000 title abstract 3
- 208000012902 Nervous system disease Diseases 0.000 title abstract 2
- 208000025966 Neurological disease Diseases 0.000 title abstract 2
- 150000002148 esters Chemical class 0.000 title abstract 2
- 230000000055 hyoplipidemic effect Effects 0.000 title abstract 2
- 230000008929 regeneration Effects 0.000 title abstract 2
- 238000011069 regeneration method Methods 0.000 title abstract 2
- 230000003612 virological effect Effects 0.000 title abstract 2
- 208000022873 Ocular disease Diseases 0.000 title 1
- 230000032683 aging Effects 0.000 title 1
- 230000001684 chronic effect Effects 0.000 abstract 2
- 208000030507 AIDS Diseases 0.000 abstract 1
- 206010002180 Anal ulcer Diseases 0.000 abstract 1
- 208000008789 Anetoderma Diseases 0.000 abstract 1
- 206010003694 Atrophy Diseases 0.000 abstract 1
- 206010007882 Cellulitis Diseases 0.000 abstract 1
- 208000001034 Frostbite Diseases 0.000 abstract 1
- HEMJJKBWTPKOJG-UHFFFAOYSA-N Gemfibrozil Chemical compound CC1=CC=C(C)C(OCCCC(C)(C)C(O)=O)=C1 HEMJJKBWTPKOJG-UHFFFAOYSA-N 0.000 abstract 1
- 206010018691 Granuloma Diseases 0.000 abstract 1
- 201000005099 Langerhans cell histiocytosis Diseases 0.000 abstract 1
- 206010025282 Lymphoedema Diseases 0.000 abstract 1
- 206010056969 Necrobiosis lipoidica diabeticorum Diseases 0.000 abstract 1
- 208000003251 Pruritus Diseases 0.000 abstract 1
- 206010040925 Skin striae Diseases 0.000 abstract 1
- 208000031439 Striae Distensae Diseases 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 206010064996 Ulcerative keratitis Diseases 0.000 abstract 1
- 206010052428 Wound Diseases 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 230000003712 anti-aging effect Effects 0.000 abstract 1
- 230000037444 atrophy Effects 0.000 abstract 1
- 229960000516 bezafibrate Drugs 0.000 abstract 1
- IIBYAHWJQTYFKB-UHFFFAOYSA-N bezafibrate Chemical compound C1=CC(OC(C)(C)C(O)=O)=CC=C1CCNC(=O)C1=CC=C(Cl)C=C1 IIBYAHWJQTYFKB-UHFFFAOYSA-N 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 201000007717 corneal ulcer Diseases 0.000 abstract 1
- 239000003246 corticosteroid Substances 0.000 abstract 1
- 229960001334 corticosteroids Drugs 0.000 abstract 1
- 208000030533 eye disease Diseases 0.000 abstract 1
- 229960003627 gemfibrozil Drugs 0.000 abstract 1
- 208000002502 lymphedema Diseases 0.000 abstract 1
- 201000008043 necrobiosis lipoidica Diseases 0.000 abstract 1
- 230000000926 neurological effect Effects 0.000 abstract 1
- 206010033675 panniculitis Diseases 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 210000004304 subcutaneous tissue Anatomy 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
- 230000001228 trophic effect Effects 0.000 abstract 1
- 231100000397 ulcer Toxicity 0.000 abstract 1
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Regeneracija mezenhima uporabom hipolipemika, estera derivata ariloksikarbonskih kiselina u mukokutanim bolestima, neurološkim bolestima, bolestima lokomotornog aparata, bolestima oka, mezenhimalnim tumorima, virusnim bolestima i protiv starenja naznačena time, što su derivati ariloksikarbonskih kiselina, u prvom redu klofibrat i fenofibrat i nova generacija ovih derivata (bezafibrat, gemfibrosil etc.) uspješno primijenjeni u liječenju kroničnih rana različite etiologije, zatim u trofičnih i verikoznih ulkusa potkoljenica i stopala, kao i kod perianalnih ulkusa oboljelih od AIDS-a, kod ozeblina (posebice u njihovoj profilaksi), u strija i tzv. cellulitisa, kod necrobiosis lipoidica, limfedema, kod akutnih i kroničnih oblika pruritisa različite etiologije, anetodermija, kod paradentoze, zatim kao antagonist kortikosteroida, ali i kod neuroloških atrofija kože i potkožja, bolestima lokomotornog aparata i bolestima oka (ulkus rožnice), kod sistemskih bolesti veziva i histiocitoze X (Granuloma eosinophylicum disseminatum), kod mezenhimalnih tumora, tj. u bolestima gdje je oštečenje mezenhima primarno ili je posljedica temeljne bolesti, a u trećoj životnoj dobi kao pripomoć u revitalizaciji.Konsenzualni patent sadrži još 3 patentna zahtjeva.Mesenchymal regeneration using hypolipemics, aryloxycarboxylic acid ester derivatives in mucocutaneous diseases, neurological diseases, diseases of the locomotor apparatus, eye diseases, mesenchymal tumors, viral diseases and anti-aging, characterized in that the derivatives of aryloxycarboxylic acids and, first and foremost, are cloenofibrate derivatives (bezafibrate, gemfibrosil, etc.) successfully used in the treatment of chronic wounds of different etiology, then in trophic and veic ulcers of the lower legs and feet, as well as in perianal ulcers of AIDS, frostbite (especially in their prophylaxis), in stretch marks and so called. cellulitis, necrobiosis lipoidica, lymphedema, acute and chronic forms of pruritus of different etiology, anetoderma, paradentosis, antagonist of corticosteroids, but also neurological atrophies of the skin and subcutaneous tissue, locomotor apparatus diseases and diseases of the eye (corneal ulcer) binders and histiocytosis X (Granuloma eosinophylicum disseminatum), in mesenchymal tumors, ie in diseases where mesenchymal damage is primary or due to underlying disease, and in the third age as an aid in revitalization.The consensual patent contains 3 more patent claims.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HRP931105AA HRPK931105B1 (en) | 1993-10-25 | 1993-10-25 | Mesenchymal regeneration by the use of hypolipemics, esters of aryloxycarbonic acid derivatives in mucocutaneous diseases, neurological diseases, diseases of locomotor system, ocular diseases, mesenchymal tumors, viral diseases and against aging |
| SI9400395A SI9400395A (en) | 1993-10-25 | 1994-10-25 | Aryloxycarbonic acid derivates and their use for mezenhim's regeneration. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HRP931105AA HRPK931105B1 (en) | 1993-10-25 | 1993-10-25 | Mesenchymal regeneration by the use of hypolipemics, esters of aryloxycarbonic acid derivatives in mucocutaneous diseases, neurological diseases, diseases of locomotor system, ocular diseases, mesenchymal tumors, viral diseases and against aging |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HRP931105A2 HRP931105A2 (en) | 1996-06-30 |
| HRPK931105B1 true HRPK931105B1 (en) | 2001-04-30 |
Family
ID=10945998
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP931105AA HRPK931105B1 (en) | 1993-10-25 | 1993-10-25 | Mesenchymal regeneration by the use of hypolipemics, esters of aryloxycarbonic acid derivatives in mucocutaneous diseases, neurological diseases, diseases of locomotor system, ocular diseases, mesenchymal tumors, viral diseases and against aging |
Country Status (2)
| Country | Link |
|---|---|
| HR (1) | HRPK931105B1 (en) |
| SI (1) | SI9400395A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102716338A (en) * | 2012-06-29 | 2012-10-10 | 遵义臻坤中草医药研究所 | Traditional Chinese medicine composition for activating human body dormancy stem cells and delaying senium |
-
1993
- 1993-10-25 HR HRP931105AA patent/HRPK931105B1/en not_active Application Discontinuation
-
1994
- 1994-10-25 SI SI9400395A patent/SI9400395A/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102716338A (en) * | 2012-06-29 | 2012-10-10 | 遵义臻坤中草医药研究所 | Traditional Chinese medicine composition for activating human body dormancy stem cells and delaying senium |
Also Published As
| Publication number | Publication date |
|---|---|
| HRP931105A2 (en) | 1996-06-30 |
| SI9400395A (en) | 1995-04-30 |
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Legal Events
| Date | Code | Title | Description |
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| A1OB | Publication of a patent application | ||
| AIPI | Request for the grant of a patent on the basis of a substantive examination of a patent application | ||
| AKOB | Publication of a request for the grant of a patent not including a substantive examination of a patent application (a consensual patent) | ||
| ODRP | Renewal fee for the maintenance of a patent |
Payment date: 20001025 Year of fee payment: 9 |
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| PNAN | Change of the applicant name, address/residence |
Owner name: MARIO GLIGORA, HR |
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| PKB1 | Consensual patent granted | ||
| AIPK | Request for the grant of a patent on the basis of a substantive examination of a patent application after grant of consensual patent | ||
| ODBI | Application refused |