HK167295A - Precursors of the HIV-2 retrovirus envelope glycoprotein and related antigens - Google Patents

Precursors of the HIV-2 retrovirus envelope glycoprotein and related antigens

Info

Publication number
HK167295A
HK167295A HK167295A HK167295A HK167295A HK 167295 A HK167295 A HK 167295A HK 167295 A HK167295 A HK 167295A HK 167295 A HK167295 A HK 167295A HK 167295 A HK167295 A HK 167295A
Authority
HK
Hong Kong
Prior art keywords
hiv
retrovirus
envelope glycoprotein
precursors
protein
Prior art date
Application number
HK167295A
Inventor
Luc Montagnier
Ara Hovanessian
Anne Laurent
Bernard Krust
Marie-Anne Rey
Original Assignee
Pasteur Institut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8807817A external-priority patent/FR2632644B1/en
Application filed by Pasteur Institut filed Critical Pasteur Institut
Publication of HK167295A publication Critical patent/HK167295A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • AIDS & HIV (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)

Abstract

The invention relates to an antigenic gp300 protein characterised by: - a molecular weight (MW) of approximately 300Kd, - the combination of two units of a gp140 glycoprotein, a precursor, in particular, of the gp125 envelope glycoprotein encoded by the env gene of the genome of an HIV-2 human retrovirus capable of causing LAS or AIDS, or the protein of a retrovirus which crosses immunologically with antibodies directed towards the said gp300 protein of the HIV-2 retrovirus. The invention also relates to the preparation of these proteins, monoclonal antibodies directed towards them and immunogenic compositions containing them.
HK167295A 1988-06-09 1995-10-26 Precursors of the HIV-2 retrovirus envelope glycoprotein and related antigens HK167295A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20434688A 1988-06-09 1988-06-09
FR8807817A FR2632644B1 (en) 1988-06-10 1988-06-10 PRECURSOR ANTIGENS OF HUMAN HIV-2 RETROVIRUS ENVELOPE GLYCOPROTEINS AND ANTIGENS HAVING AN IMMUNOLOGICAL PARENT TO THESE LATTERS. PREPARATION OF THESE ANTIGENS. APPLICATION TO DIAGNOSIS

Publications (1)

Publication Number Publication Date
HK167295A true HK167295A (en) 1995-11-03

Family

ID=26226719

Family Applications (1)

Application Number Title Priority Date Filing Date
HK167295A HK167295A (en) 1988-06-09 1995-10-26 Precursors of the HIV-2 retrovirus envelope glycoprotein and related antigens

Country Status (9)

Country Link
EP (1) EP0354072B1 (en)
JP (1) JP3093763B2 (en)
AT (1) ATE122236T1 (en)
CA (1) CA1341488C (en)
DE (1) DE68922540T2 (en)
DK (1) DK175668B1 (en)
ES (1) ES2074085T3 (en)
HK (1) HK167295A (en)
PT (1) PT90800B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005078443A1 (en) * 2004-02-13 2005-08-25 Inverness Medical Switzerland Gmbh Determination of infection by the immune response to a carbohydrate moiety

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0249611A4 (en) * 1985-11-14 1988-04-26 Harvard College T-lymphotrophic virus.
EP0269520A3 (en) * 1986-11-21 1988-08-24 Institut Pasteur Retrovirus of the type hiv-2, susceptible to provoke aids, and its antigenic and nucleic-acid constituents
WO1988005440A1 (en) * 1987-01-16 1988-07-28 Institut Pasteur Peptides having immunological properties 2-hiv-2

Also Published As

Publication number Publication date
DE68922540D1 (en) 1995-06-14
EP0354072A1 (en) 1990-02-07
EP0354072B1 (en) 1995-05-10
CA1341488C (en) 2005-08-30
DK284389D0 (en) 1989-06-09
DE68922540T2 (en) 1995-10-05
DK284389A (en) 1989-12-10
PT90800A (en) 1989-12-29
JPH02119791A (en) 1990-05-07
PT90800B (en) 1994-11-30
DK175668B1 (en) 2005-01-10
ES2074085T3 (en) 1995-09-01
ATE122236T1 (en) 1995-05-15
JP3093763B2 (en) 2000-10-03

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Legal Events

Date Code Title Description
PF Patent in force
PE Patent expired

Effective date: 20090608