HK1246694A1 - α胸腺肽用於脓毒症治疗的用途 - Google Patents

α胸腺肽用於脓毒症治疗的用途 Download PDF

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Publication number
HK1246694A1
HK1246694A1 HK18106506.4A HK18106506A HK1246694A1 HK 1246694 A1 HK1246694 A1 HK 1246694A1 HK 18106506 A HK18106506 A HK 18106506A HK 1246694 A1 HK1246694 A1 HK 1246694A1
Authority
HK
Hong Kong
Prior art keywords
sepsis
days
thymosin peptide
alpha
administered
Prior art date
Application number
HK18106506.4A
Other languages
English (en)
Chinese (zh)
Inventor
管向東
管向东
吳健鋒
吴健锋
C．塔特希爾
C.塔特希尔
Original Assignee
Sciclone Pharmaceuticals International (Sg) Pte. Ltd.
中山大学附属第一医院
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sciclone Pharmaceuticals International (Sg) Pte. Ltd., 中山大学附属第一医院 filed Critical Sciclone Pharmaceuticals International (Sg) Pte. Ltd.
Publication of HK1246694A1 publication Critical patent/HK1246694A1/zh

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2292—Thymosin; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HK18106506.4A 2012-03-30 2018-05-18 α胸腺肽用於脓毒症治疗的用途 HK1246694A1 (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201261618563P 2012-03-30 2012-03-30
US61/618,563 2012-03-30
US201261643824P 2012-05-07 2012-05-07
US61/643,824 2012-05-07
US13/835,107 US20130296223A1 (en) 2012-03-30 2013-03-15 Use of thymosin alpha for the treatment of sepsis
US13/835,107 2013-03-15

Publications (1)

Publication Number Publication Date
HK1246694A1 true HK1246694A1 (zh) 2018-09-14

Family

ID=49261395

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18106506.4A HK1246694A1 (zh) 2012-03-30 2018-05-18 α胸腺肽用於脓毒症治疗的用途

Country Status (8)

Country Link
US (5) US20130296223A1 (https=)
EP (2) EP3741386A1 (https=)
JP (6) JP2015514093A (https=)
KR (1) KR20150048663A (https=)
CN (2) CN105338996A (https=)
CA (1) CA2866435A1 (https=)
HK (1) HK1246694A1 (https=)
WO (1) WO2013149030A2 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2015303147A1 (en) * 2014-08-12 2017-02-23 Arsanis Biosciences Gmbh Predicting S. aureus disease
WO2019028448A1 (en) * 2017-08-04 2019-02-07 The Johns Hopkins University APPLICATION FOR EARLY PREDICTION OF SEPTIC SHOCK WAITING
US11504071B2 (en) * 2018-04-10 2022-11-22 Hill-Rom Services, Inc. Patient risk assessment based on data from multiple sources in a healthcare facility
FI3781210T3 (fi) * 2018-04-20 2024-09-12 Combioxin Sa Hypotension hoito sepsiksen tai septisen sokin yhteydessä
EP4370129A1 (en) 2021-07-12 2024-05-22 2N Pharma ApS Carnitine-palmitoyl-transferase-1 (cpt-1) inhibitors for use in a method of preventing or treating sepsis in a mammalian subject

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4079127A (en) 1976-10-28 1978-03-14 Board Of Regents Of The University Of Texas Thymosin alpha 1
TW252045B (https=) * 1993-10-07 1995-07-21 Allan L Goldstein
AU7964194A (en) * 1993-10-07 1995-05-01 George Washington University Medical Center, The Method of treating septic shock using thymosin-alpha1
US5972933A (en) * 1998-01-08 1999-10-26 Ed. Geistlich Sohne Ag Fur Chemische Industrie Method of treating microbial infections
UA80957C2 (en) 2001-11-01 2007-11-26 Sciclone Pharmaceuticals Inc Method of administering a thymosin alpha 1 peptide
PL377376A1 (pl) * 2002-11-25 2006-02-06 Sciclone Pharmaceuticals, Inc. Sposoby ochrony przed uszkodzeniem przez promieniowanie z użyciem Ó-tymozyny
MX348936B (es) * 2005-09-29 2017-07-03 Nektar Therapeutics Formulaciones de antibioticos, dosis unitarias, equipos y metodos.
CN101020048A (zh) * 2007-02-12 2007-08-22 广东天普生化医药股份有限公司 一种用于治疗脓毒症的药物组合物
JP2010522192A (ja) * 2007-03-21 2010-07-01 ボーシュ アンド ローム インコーポレイティド 抗菌薬耐性のバクテリアによって引き起こされる感染症を治療、軽減、寛解、又は予防するための組成物及び方法
JP2011506436A (ja) * 2007-12-12 2011-03-03 サイクローン・ファーマシューティカルズ・インコーポレイテッド 細胞傷害性ｔリンパ球抗原４（ｃｔｌａ４）に対する抗体と組み合わせられたアルファチモシンペプチドによる黒色腫の処置の方法
CN101514228A (zh) * 2008-02-21 2009-08-26 张卓兵 N-端修饰的人胸腺肽α1复合物及其制备方法
EP2427213B1 (en) * 2009-05-08 2015-04-01 Sciclone Pharmaceuticals, Inc. Alpha thymosin peptides as vaccine enhancers
US20130225477A1 (en) * 2010-02-25 2013-08-29 Agennix Ag Oral Lactoferrin in the Treatment of Severe Sepsis
WO2012109106A1 (en) * 2011-02-09 2012-08-16 Sciclone Pharmaceuticals, Inc. Thymosin alpha peptide for preventing, reducing the severity of, and treating infection

Also Published As

Publication number Publication date
JP2019156854A (ja) 2019-09-19
HK1207314A1 (en) 2016-01-29
JP2025107346A (ja) 2025-07-17
JP2022176345A (ja) 2022-11-25
WO2013149030A2 (en) 2013-10-03
JP2017214377A (ja) 2017-12-07
US20150024994A1 (en) 2015-01-22
JP2015514093A (ja) 2015-05-18
US20240091314A1 (en) 2024-03-21
CN107519483A (zh) 2017-12-29
CN105338996A (zh) 2016-02-17
EP3741386A1 (en) 2020-11-25
JP2021100983A (ja) 2021-07-08
EP2841088A4 (en) 2015-10-14
CA2866435A1 (en) 2013-10-03
US20180236036A1 (en) 2018-08-23
EP2841088B1 (en) 2020-06-17
US20130296223A1 (en) 2013-11-07
US20210106656A1 (en) 2021-04-15
EP2841088A2 (en) 2015-03-04
KR20150048663A (ko) 2015-05-07

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