HK1245775A1 - Salts as hepatitis c virus inhibitors - Google Patents

Salts as hepatitis c virus inhibitors

Info

Publication number
HK1245775A1
HK1245775A1 HK18105168.5A HK18105168A HK1245775A1 HK 1245775 A1 HK1245775 A1 HK 1245775A1 HK 18105168 A HK18105168 A HK 18105168A HK 1245775 A1 HK1245775 A1 HK 1245775A1
Authority
HK
Hong Kong
Prior art keywords
hepatitis
salts
virus inhibitors
virus
inhibitors
Prior art date
Application number
HK18105168.5A
Other languages
Chinese (zh)
Inventor
任青雲
陳亮
單岳峰
羅慧超
梁金勝
黃建洲
熊金峰
張道俊
張英俊
張健存
Original Assignee
廣東東陽光藥業有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 廣東東陽光藥業有限公司 filed Critical 廣東東陽光藥業有限公司
Publication of HK1245775A1 publication Critical patent/HK1245775A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK18105168.5A 2016-08-11 2018-04-20 Salts as hepatitis c virus inhibitors HK1245775A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610655907 2016-08-11

Publications (1)

Publication Number Publication Date
HK1245775A1 true HK1245775A1 (en) 2018-08-31

Family

ID=61162862

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18105168.5A HK1245775A1 (en) 2016-08-11 2018-04-20 Salts as hepatitis c virus inhibitors

Country Status (4)

Country Link
CN (1) CN107722014B (en)
HK (1) HK1245775A1 (en)
TW (1) TW201805289A (en)
WO (1) WO2018028634A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110117287B (en) * 2018-02-07 2020-09-11 广东东阳光药业有限公司 Salts as hepatitis c virus inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101580535B (en) * 2008-05-16 2012-10-03 太景生物科技股份有限公司 Hcv protease inhibitors
US20100196321A1 (en) * 2009-01-30 2010-08-05 Glaxosmithkline Llc Compounds
WO2012040242A1 (en) * 2010-09-22 2012-03-29 Intermune, Inc. Substituted proline inhibitors of hepatitis c virus replication
CN105884779B (en) * 2015-02-13 2018-06-12 广东东阳光药业有限公司 Application as the compound of hepatitis c inhibitor and its in drug

Also Published As

Publication number Publication date
CN107722014A (en) 2018-02-23
TW201805289A (en) 2018-02-16
CN107722014B (en) 2020-07-07
WO2018028634A1 (en) 2018-02-15

Similar Documents

Publication Publication Date Title
HK1255847A1 (en) Vaccines against hepatitis b virus
IL280459A (en) Phosphoramidates for the treatment of hepatitis b virus
GB201406608D0 (en) Virus
HK1257565A1 (en) New trifluoromethylpropanamide derivatives as htra1 inhibitors
HK1257567A1 (en) New difluoroketamide derivatives as htra1 inhibitors
HK1249514A1 (en) Inhibitors of hepatitis c virus polymerase
GB201419572D0 (en) Virus
GB201402169D0 (en) Viral inhibitors
ZA201703115B (en) Long acting pharmaceutical compositions for hepatitis c
IL252016A0 (en) Combination long acting compositions and methods for hepatitis c
HK1245775A1 (en) Salts as hepatitis c virus inhibitors
SG11201610453SA (en) Compounds for inhibiting hepatitis c virus, pharmaceutical compositions and uses thereof
EP3445367A4 (en) Hepatitis c virus inhibitors
GB201600380D0 (en) Modified virus
GB201522013D0 (en) Virus
GB201516936D0 (en) Virus
GB201507419D0 (en) Virus
ES1133530Y (en) PERFECTED SHOCK
GB201408266D0 (en) Liver infection
TH1501004918A (en) Amide compounds for HIV therapy
GB201406470D0 (en) Virus
GB201403582D0 (en) Virus