HK1245272B - 新型1，4-雙(3-氨基丙基)哌嗪衍生物及其用途 - Google Patents

新型1，4-雙(3-氨基丙基)哌嗪衍生物及其用途

Info

Publication number
HK1245272B
HK1245272B HK18104874.3A HK18104874A HK1245272B HK 1245272 B HK1245272 B HK 1245272B HK 18104874 A HK18104874 A HK 18104874A HK 1245272 B HK1245272 B HK 1245272B
Authority
HK
Hong Kong
Prior art keywords
aminopropyl
bis
novel
piperazine derivative
piperazine
Prior art date
Application number
HK18104874.3A
Other languages
English (en)
Inventor
Sergeant Nicolas
Buee Luc
Melnyk Patricia
GAY Marion
Le Fur Nicolas
Original Assignee
Inst Nat Sante Rech Med
Centre Hospitalier Regional Et Univ De Lille Chru
Univ Lille Ii Droit & Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Nat Sante Rech Med, Centre Hospitalier Regional Et Univ De Lille Chru, Univ Lille Ii Droit & Sante filed Critical Inst Nat Sante Rech Med
Publication of HK1245272B publication Critical patent/HK1245272B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9
    • C07D219/12—Amino-alkylamino radicals attached in position 9
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
HK18104874.3A 2015-03-16 2018-04-13 新型1，4-雙(3-氨基丙基)哌嗪衍生物及其用途 HK1245272B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15305384 2015-03-16
PCT/EP2016/055633 WO2016146655A1 (en) 2015-03-16 2016-03-16 Novel 1,4-bis(3-aminopropyl)piperazine derivative and its use

Publications (1)

Publication Number Publication Date
HK1245272B true HK1245272B (zh) 2019-09-27

Family

ID=52684177

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18104874.3A HK1245272B (zh) 2015-03-16 2018-04-13 新型1，4-雙(3-氨基丙基)哌嗪衍生物及其用途

Country Status (8)

Country Link
US (3) US10017476B2 (zh)
EP (1) EP3271335B8 (zh)
JP (1) JP6649396B2 (zh)
CN (1) CN107466292B (zh)
DK (1) DK3271335T3 (zh)
ES (1) ES2715960T3 (zh)
HK (1) HK1245272B (zh)
WO (1) WO2016146655A1 (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI744300B (zh) * 2016-03-23 2021-11-01 里爾中央醫學中心 改良性熱處理的血小板顆粒裂解液在製備用於治療神經系統疾病的組合物的用途
KR20230083330A (ko) 2020-10-07 2023-06-09 알즈프로텍트 운동 뉴런 질환 및 신경근 접합 장애 치료를 위한 N-(3-(4-(3-(다이이소부틸아미노)프로필)피페라진-1-일)프로필)-1H-벤조[d]이미다졸-2-아민 황산염 및 이의 용매화물의 용도

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1809288B1 (en) 2004-11-10 2011-09-14 Institut National De La Sante Et De La Recherche Medicale (Inserm) Use of 1,4-bis (3-aminoalkyl) piperazine derivatives in the treatment of neurodegenerative diseases
WO2014028777A2 (en) 2012-08-16 2014-02-20 Ipierian, Inc. Methods of treating a tauopathy
EP2938597B1 (en) 2012-12-27 2016-10-26 Alzprotect Sulphate salts of n-(3-(4-(3-(diisobutylamino)propyl)piperazin-1-yl)propyl)-1h-benzo[d]imidazol-2-amine, preparation thereof and use of the same

Also Published As

Publication number Publication date
US10807958B2 (en) 2020-10-20
US20200407325A1 (en) 2020-12-31
EP3271335B8 (en) 2019-03-27
ES2715960T3 (es) 2019-06-07
CN107466292A (zh) 2017-12-12
CN107466292B (zh) 2020-05-01
JP6649396B2 (ja) 2020-02-19
US20180072679A1 (en) 2018-03-15
EP3271335A1 (en) 2018-01-24
US10017476B2 (en) 2018-07-10
DK3271335T3 (en) 2019-04-01
EP3271335B1 (en) 2018-12-26
WO2016146655A1 (en) 2016-09-22
JP2018507906A (ja) 2018-03-22
US20180290981A1 (en) 2018-10-11

Similar Documents

Publication Publication Date Title
HK1254654A1 (zh) 4，6-亞嘧啶基衍生物及其用途
PL3407888T3 (pl) Związki pirydopirolochinoksaliny, ich kompozycje i zastosowania
IL246987B (en) Heteroaryl amides, preparations containing it and their uses
IL272055A (en) 8,1-naphthyridinone compounds and their uses
HK1254379A1 (zh) 烯基苯氧基取代的1，1-二苯基乙烯、它們的製備方法和它們的用途
SG11201803584RA (en) 1,4-dicarbonyl-piperidyl derivatives
HK1254800A1 (zh) 2，3，4，5-四氫吡啶-6-胺衍生物
HK1245272B (zh) 新型1，4-雙(3-氨基丙基)哌嗪衍生物及其用途
IL249122A0 (en) History of imidazole- or 4,2,1-triazole and their use
GB201718324D0 (en) Zenaura 1
PL3386988T3 (pl) Nowe pochodne dihydropiranopirymidynonu i ich zastosowanie
IL259900A (en) Aminoazole derivatives, compositions containing same and uses thereof
GB201717334D0 (en) Perfect 11
AU201717501S (en) Table
AU201810142S (en) Tables
AU201810141S (en) Tables
AU201810137S (en) Tables
AU201810136S (en) Tables
AU201810135S (en) Tables
AU201810145S (en) Tables
AU201810155S (en) Tables
AU201715147S (en) Table
AU201715146S (en) Table
AU201715145S (en) Table
AU201715148S (en) Table