HK1245272B - 新型1,4-雙(3-氨基丙基)哌嗪衍生物及其用途 - Google Patents
新型1,4-雙(3-氨基丙基)哌嗪衍生物及其用途Info
- Publication number
- HK1245272B HK1245272B HK18104874.3A HK18104874A HK1245272B HK 1245272 B HK1245272 B HK 1245272B HK 18104874 A HK18104874 A HK 18104874A HK 1245272 B HK1245272 B HK 1245272B
- Authority
- HK
- Hong Kong
- Prior art keywords
- aminopropyl
- bis
- novel
- piperazine derivative
- piperazine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/08—Nitrogen atoms
- C07D219/10—Nitrogen atoms attached in position 9
- C07D219/12—Amino-alkylamino radicals attached in position 9
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP15305384 | 2015-03-16 | ||
PCT/EP2016/055633 WO2016146655A1 (en) | 2015-03-16 | 2016-03-16 | Novel 1,4-bis(3-aminopropyl)piperazine derivative and its use |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1245272B true HK1245272B (zh) | 2019-09-27 |
Family
ID=52684177
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18104874.3A HK1245272B (zh) | 2015-03-16 | 2018-04-13 | 新型1,4-雙(3-氨基丙基)哌嗪衍生物及其用途 |
Country Status (8)
Country | Link |
---|---|
US (3) | US10017476B2 (zh) |
EP (1) | EP3271335B8 (zh) |
JP (1) | JP6649396B2 (zh) |
CN (1) | CN107466292B (zh) |
DK (1) | DK3271335T3 (zh) |
ES (1) | ES2715960T3 (zh) |
HK (1) | HK1245272B (zh) |
WO (1) | WO2016146655A1 (zh) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI744300B (zh) * | 2016-03-23 | 2021-11-01 | 里爾中央醫學中心 | 改良性熱處理的血小板顆粒裂解液在製備用於治療神經系統疾病的組合物的用途 |
KR20230083330A (ko) | 2020-10-07 | 2023-06-09 | 알즈프로텍트 | 운동 뉴런 질환 및 신경근 접합 장애 치료를 위한 N-(3-(4-(3-(다이이소부틸아미노)프로필)피페라진-1-일)프로필)-1H-벤조[d]이미다졸-2-아민 황산염 및 이의 용매화물의 용도 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1809288B1 (en) | 2004-11-10 | 2011-09-14 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Use of 1,4-bis (3-aminoalkyl) piperazine derivatives in the treatment of neurodegenerative diseases |
WO2014028777A2 (en) | 2012-08-16 | 2014-02-20 | Ipierian, Inc. | Methods of treating a tauopathy |
EP2938597B1 (en) | 2012-12-27 | 2016-10-26 | Alzprotect | Sulphate salts of n-(3-(4-(3-(diisobutylamino)propyl)piperazin-1-yl)propyl)-1h-benzo[d]imidazol-2-amine, preparation thereof and use of the same |
-
2016
- 2016-03-16 JP JP2017548992A patent/JP6649396B2/ja active Active
- 2016-03-16 CN CN201680013830.5A patent/CN107466292B/zh active Active
- 2016-03-16 WO PCT/EP2016/055633 patent/WO2016146655A1/en active Application Filing
- 2016-03-16 DK DK16710161.7T patent/DK3271335T3/en active
- 2016-03-16 US US15/558,921 patent/US10017476B2/en active Active
- 2016-03-16 EP EP16710161.7A patent/EP3271335B8/en active Active
- 2016-03-16 ES ES16710161T patent/ES2715960T3/es active Active
-
2018
- 2018-04-13 HK HK18104874.3A patent/HK1245272B/zh unknown
- 2018-06-15 US US16/009,979 patent/US10807958B2/en active Active
-
2020
- 2020-09-14 US US17/020,318 patent/US20200407325A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US10807958B2 (en) | 2020-10-20 |
US20200407325A1 (en) | 2020-12-31 |
EP3271335B8 (en) | 2019-03-27 |
ES2715960T3 (es) | 2019-06-07 |
CN107466292A (zh) | 2017-12-12 |
CN107466292B (zh) | 2020-05-01 |
JP6649396B2 (ja) | 2020-02-19 |
US20180072679A1 (en) | 2018-03-15 |
EP3271335A1 (en) | 2018-01-24 |
US10017476B2 (en) | 2018-07-10 |
DK3271335T3 (en) | 2019-04-01 |
EP3271335B1 (en) | 2018-12-26 |
WO2016146655A1 (en) | 2016-09-22 |
JP2018507906A (ja) | 2018-03-22 |
US20180290981A1 (en) | 2018-10-11 |
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