HK1232289A1 - 分拣蛋白作为针对情感/心境障碍的生物标记的用途 - Google Patents

分拣蛋白作为针对情感/心境障碍的生物标记的用途 Download PDF

Info

Publication number
HK1232289A1
HK1232289A1 HK17105802.8A HK17105802A HK1232289A1 HK 1232289 A1 HK1232289 A1 HK 1232289A1 HK 17105802 A HK17105802 A HK 17105802A HK 1232289 A1 HK1232289 A1 HK 1232289A1
Authority
HK
Hong Kong
Prior art keywords
sortilin
biomarker
affective
mood disorders
levels
Prior art date
Application number
HK17105802.8A
Other languages
English (en)
Chinese (zh)
Inventor
.耶普森
J.L.耶普森
.尼科耶爾
A.尼科耶尔
.莫斯
N.P.O.莫斯
.彼得森
C.M.彼得森
.厄斯特高
S.D.厄斯特高
.格萊若普
S.格莱若普
Original Assignee
H. Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S
Publication of HK1232289A1 publication Critical patent/HK1232289A1/zh

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/30Psychoses; Psychiatry
    • G01N2800/304Mood disorders, e.g. bipolar, depression
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK17105802.8A 2014-02-12 2015-02-06 分拣蛋白作为针对情感/心境障碍的生物标记的用途 HK1232289A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA201400075 2014-02-12
DKPA201400075 2014-02-12
PCT/EP2015/052506 WO2015121166A1 (en) 2014-02-12 2015-02-06 Use of sortilin as biomarker for affective/mood disorders

Publications (1)

Publication Number Publication Date
HK1232289A1 true HK1232289A1 (zh) 2018-01-05

Family

ID=52462923

Family Applications (1)

Application Number Title Priority Date Filing Date
HK17105802.8A HK1232289A1 (zh) 2014-02-12 2015-02-06 分拣蛋白作为针对情感/心境障碍的生物标记的用途

Country Status (6)

Country Link
US (1) US20160349276A1 (https=)
EP (1) EP3105594A1 (https=)
JP (1) JP2017508144A (https=)
CN (1) CN105980858A (https=)
HK (1) HK1232289A1 (https=)
WO (1) WO2015121166A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10849992B1 (en) 2015-04-07 2020-12-01 Alector Llc Methods of screening for sortilin binding antagonists
CN107708733B (zh) 2015-04-07 2022-11-15 艾利妥 抗分拣蛋白抗体和其使用方法
FR3057267A1 (fr) * 2016-10-11 2018-04-13 Centre National De La Recherche Scientifique - Cnrs - Procede de diagnostic/determination de l'efficacite de traitement de la depression
US11622948B2 (en) 2017-11-09 2023-04-11 The Trustees Of Columbia University In The City Of New York Biomarkers for efficacy of prophylactic treatments against stress-induced affective disorders
US11491120B2 (en) 2017-11-09 2022-11-08 The Trustees Of Columbia University In The City Of New York Pharmacological prophylactics against stress-induced affective disorders in females
TWI809147B (zh) 2018-07-13 2023-07-21 美商阿列克特有限責任公司 抗分揀蛋白抗體及其使用方法
CN111351945B (zh) * 2020-03-18 2021-04-23 东南大学 维生素d结合蛋白作为标志物在精神疾病抑郁症诊断中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3165537A1 (en) * 2008-12-19 2017-05-10 H. Lundbeck A/S Modulation of the vps 10-domain receptor family for the treatment of mental and behavioural disorders
GB0903417D0 (en) * 2009-02-27 2009-04-08 Cambridge Entpr Ltd Biomarkers
GB0922240D0 (en) * 2009-12-21 2010-02-03 Cambridge Entpr Ltd Biomarkers
GB201021502D0 (en) * 2010-12-20 2011-02-02 Cambridge Entpr Ltd Biomarkers

Also Published As

Publication number Publication date
JP2017508144A (ja) 2017-03-23
EP3105594A1 (en) 2016-12-21
US20160349276A1 (en) 2016-12-01
CN105980858A (zh) 2016-09-28
WO2015121166A1 (en) 2015-08-20

Similar Documents

Publication Publication Date Title
HK1232289A1 (zh) 分拣蛋白作为针对情感/心境障碍的生物标记的用途
PL3297644T3 (pl) Metody terapii zaburzeń ze spektrum autyzmu i powiązanych objawów
GB2551642B (en) Methods and compositions relating to microbial treatment and diagnosis of disorders
MX381640B (es) Metodos y compuestos agonistas de gip.
IL246917A0 (en) Biomarker and early diagnosis methods for Alzheimer's disease
IL282923A (en) Methods and preparations for the diagnosis and treatment of disorders in patients with high levels of chemokine C.-X.-C. Ligand 9 and other biomarkers
EA201890111A1 (ru) Замещенные производные оксопиридина
IL256166B (en) Compounds for use in treating neuromuscular disorders
HUE059559T2 (hu) 5HT agonisták az epilepsziás rendellenességek kezelésére
NZ720949A (en) Methods and compositions for treating aging-associated conditions
EA201591417A1 (ru) Новый способ диагностики депрессии и мониторинга эффективности терапии
LT3882250T (lt) Tetrahidropiranilamino-pirolopirimidinonas, skirtas panaudoti btk nulemtų sutrikimų gydymui
EP2560681A4 (en) USE OF TAU FOR MONITORING IMMUNOTHERAPY
EA201692529A1 (ru) Способы и композиции для лечения расстройств с использованием фоллистатиновых полипептидов
FI20145492A7 (fi) Menetelmä Parkinsonin taudin diagnostiikkaan, hoitoon ja estämiseen
PT3200582T (pt) Composições, kits e métodos para induzir citorresistência adquirida com utilização de indutores de proteínas de stress
EA201790769A1 (ru) Определение уровней гликозаминогликанов методом масс-спектрометрии
EP3142664A4 (en) Compositions and methods for treating and diagnosing ocular disorders
MX2018000528A (es) Dispositivo para la deteccion de proteinas mal plegadas y metodos de uso del mismo.
EP3218481A4 (en) Biomarkers useful in the treatment of subjects having diseases of the eye
IN2014DN08398A (https=)
MA40406A (fr) Procédés et compositions de diagnostic et de traitement des maladies inflammatoires chroniques de l'intestin
MX377026B (es) Biomarcadores para la progresión de enfermedades en melanoma.
EP3307775A4 (en) Methods for diagnosing and treating affective disorders
SG11201706249RA (en) Biomarkers for diagnosis and prognosis of corneal ectatic disorders