HK1231493A1 - 药学上相关的芳香族阳离子肽 - Google Patents
药学上相关的芳香族阳离子肽 Download PDFInfo
- Publication number
- HK1231493A1 HK1231493A1 HK17105171.1A HK17105171A HK1231493A1 HK 1231493 A1 HK1231493 A1 HK 1231493A1 HK 17105171 A HK17105171 A HK 17105171A HK 1231493 A1 HK1231493 A1 HK 1231493A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- cationic peptides
- pharmaceutically relevant
- peptides
- relevant aromatic
- phe
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1021—Tetrapeptides with the first amino acid being acidic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
- C07K5/0817—Tripeptides with the first amino acid being basic the first amino acid being Arg
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461947286P | 2014-03-03 | 2014-03-03 | |
| US201461947286P | 2014-03-03 | ||
| PCT/US2014/072267 WO2015134096A1 (en) | 2014-03-03 | 2014-12-23 | Pharmaceutically relevant aromatic-cationic peptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1231493A1 true HK1231493A1 (zh) | 2017-12-22 |
Family
ID=54055710
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK17105171.1A HK1231493A1 (zh) | 2014-03-03 | 2014-12-23 | 药学上相关的芳香族阳离子肽 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20170081363A1 (https=) |
| EP (1) | EP3114136A4 (https=) |
| JP (1) | JP2017512762A (https=) |
| CN (1) | CN106459169A (https=) |
| CA (1) | CA2942143A1 (https=) |
| HK (1) | HK1231493A1 (https=) |
| WO (1) | WO2015134096A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6626446B2 (ja) * | 2013-12-27 | 2019-12-25 | ステルス バイオセラピューティックス コープ | 薬学的に適切な芳香族カチオン性ペプチド |
| US10633415B2 (en) | 2015-03-06 | 2020-04-28 | Stealth Biotherapeutics Corp | Processes for preparing pharmaceutically relevant peptides |
| JPWO2017043626A1 (ja) * | 2015-09-11 | 2018-06-21 | 株式会社カネカ | 光学活性４−カルバモイル−２，６−ジメチルフェニルアラニン誘導体の製造法 |
| CA3020393A1 (en) | 2016-04-11 | 2017-10-19 | Carnot, Llc | Chiral peptides |
| CN110914287A (zh) | 2017-04-05 | 2020-03-24 | 隐形生物治疗公司 | Boc-d-arg-dmt-lys-(boc)-phe-nh2的结晶盐形式 |
| US20200361987A1 (en) * | 2017-11-15 | 2020-11-19 | Stealth Biotherapeutics Corp. | Deuterated tetrapeptides that target mitochondria |
| US10676506B2 (en) | 2018-01-26 | 2020-06-09 | Stealth Biotherapeutics Corp. | Crystalline bis- and tris-hydrochloride salt of elamipretide |
| EP3898653A4 (en) | 2018-12-18 | 2022-08-24 | Stealth BioTherapeutics Inc. | ANALOGS TARGETING MITOCHONDRIAL DISEASES |
| TW202346255A (zh) * | 2022-01-06 | 2023-12-01 | 日商中外製藥股份有限公司 | 醯胺化合物的製造方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7214663B2 (en) * | 2000-06-14 | 2007-05-08 | Medarex, Inc. | Tripeptide prodrug compounds |
| JP4879020B2 (ja) * | 2003-05-01 | 2012-02-15 | コーネル リサーチ ファウンデイション インコーポレイテッド | 細胞に分子を送達する方法及び担体複合体 |
| US20070213505A1 (en) * | 2006-03-08 | 2007-09-13 | David Epstein | Solution Synthesis of Peptide Cell Growth Stimulators |
| EP3375449A1 (en) * | 2010-03-15 | 2018-09-19 | Stealth Peptides International, Inc. | Combination therapies using cyclosporine and aromatic cationic peptides |
| AU2012271691A1 (en) * | 2011-06-14 | 2014-01-16 | Stealth Peptides International, Inc. | Aromatic-cationic peptides and uses of same |
| HK1204988A1 (en) * | 2012-02-22 | 2015-12-11 | Stealth Peptides International, Inc. | Methods and compositions for preventing or treating ophthalmic conditions |
| EP2928562A4 (en) * | 2012-12-06 | 2016-06-22 | Stealth Peptides Int Inc | PEPTIDE THERAPEUTIC PRODUCTS AND METHODS OF USE |
-
2014
- 2014-12-23 HK HK17105171.1A patent/HK1231493A1/zh unknown
- 2014-12-23 EP EP14884543.1A patent/EP3114136A4/en not_active Withdrawn
- 2014-12-23 US US15/123,437 patent/US20170081363A1/en not_active Abandoned
- 2014-12-23 CN CN201480078597.XA patent/CN106459169A/zh active Pending
- 2014-12-23 WO PCT/US2014/072267 patent/WO2015134096A1/en not_active Ceased
- 2014-12-23 CA CA2942143A patent/CA2942143A1/en not_active Abandoned
- 2014-12-23 JP JP2016555478A patent/JP2017512762A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN106459169A (zh) | 2017-02-22 |
| EP3114136A1 (en) | 2017-01-11 |
| US20170081363A1 (en) | 2017-03-23 |
| JP2017512762A (ja) | 2017-05-25 |
| WO2015134096A1 (en) | 2015-09-11 |
| CA2942143A1 (en) | 2015-09-11 |
| EP3114136A4 (en) | 2017-11-01 |
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