HK1226095B - Mn/ca ix-specific monoclonal antibodies generated from mn/ca ix-deficient mice and methods of use - Google Patents

Mn/ca ix-specific monoclonal antibodies generated from mn/ca ix-deficient mice and methods of use Download PDF

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Publication number
HK1226095B
HK1226095B HK16114292.8A HK16114292A HK1226095B HK 1226095 B HK1226095 B HK 1226095B HK 16114292 A HK16114292 A HK 16114292A HK 1226095 B HK1226095 B HK 1226095B
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HK
Hong Kong
Prior art keywords
antibodies
protein
cells
antibody
domain
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HK16114292.8A
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German (de)
English (en)
French (fr)
Chinese (zh)
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HK1226095A1 (en
Inventor
Jaromir Pastorek
Silvia Pastorekova
Miriam Zatovicova
Jan Zavada
Marta Ortova Gut
Zuzanna Zavadova
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Institute Of Virology
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Publication of HK1226095A1 publication Critical patent/HK1226095A1/en
Publication of HK1226095B publication Critical patent/HK1226095B/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/82—Translation products from oncogenes

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
HK16114292.8A 2002-02-21 2016-12-15 Mn/ca ix-specific monoclonal antibodies generated from mn/ca ix-deficient mice and methods of use HK1226095B (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US35882402P 2002-02-21 2002-02-21
US358824P 2002-02-21
US38306802P 2002-05-23 2002-05-23
US383068P 2002-05-23
US43149902P 2002-12-05 2002-12-05
US431499P 2002-12-05

Publications (2)

Publication Number Publication Date
HK1226095A1 HK1226095A1 (en) 2017-09-22
HK1226095B true HK1226095B (en) 2017-09-22

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
HK16114292.8A HK1226095B (en) 2002-02-21 2016-12-15 Mn/ca ix-specific monoclonal antibodies generated from mn/ca ix-deficient mice and methods of use

Country Status (9)

Country Link
US (5) US7846673B2 (OSRAM)
EP (1) EP1487972B1 (OSRAM)
JP (4) JP4488351B2 (OSRAM)
AU (1) AU2003217606C1 (OSRAM)
CA (1) CA2477163C (OSRAM)
DK (2) DK3031910T3 (OSRAM)
HK (1) HK1226095B (OSRAM)
HU (3) HUE026218T2 (OSRAM)
WO (1) WO2004005348A1 (OSRAM)

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Also Published As

Publication number Publication date
AU2003217606A1 (en) 2003-12-12
US20050031623A1 (en) 2005-02-10
EP1487972B1 (en) 2015-08-12
JP2009114198A (ja) 2009-05-28
US7816493B2 (en) 2010-10-19
JP5271443B2 (ja) 2013-08-21
JP2013060452A (ja) 2013-04-04
EP1487972A4 (en) 2006-05-31
AU2003217606C1 (en) 2008-07-17
US7846673B2 (en) 2010-12-07
HUE036891T2 (hu) 2018-08-28
JP2005535601A (ja) 2005-11-24
US20080176258A1 (en) 2008-07-24
CA2477163A1 (en) 2003-12-04
JP4488351B2 (ja) 2010-06-23
HK1177474A1 (en) 2013-08-23
JP4514820B2 (ja) 2010-07-28
HUE026218T2 (en) 2016-05-30
CA2477163C (en) 2010-07-27
AU2003217606B8 (en) 2003-12-12
US7833728B2 (en) 2010-11-16
WO2004005348A1 (en) 2004-01-15
US20080177046A1 (en) 2008-07-24
US20080176310A1 (en) 2008-07-24
DK3031910T3 (en) 2017-10-23
HUE026277T2 (en) 2016-05-30
DK1487972T3 (en) 2015-10-19
JP2010111679A (ja) 2010-05-20
AU2003217606B2 (en) 2007-11-22
EP1487972A2 (en) 2004-12-22
AU2003217606A2 (en) 2003-12-12
US20150266971A1 (en) 2015-09-24
JP5199228B2 (ja) 2013-05-15

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Effective date: 20220224