HK1220234A1 - 化學修飾的連接酶輔因子、供體和受體 - Google Patents

化學修飾的連接酶輔因子、供體和受體

Info

Publication number
HK1220234A1
HK1220234A1 HK16108230.5A HK16108230A HK1220234A1 HK 1220234 A1 HK1220234 A1 HK 1220234A1 HK 16108230 A HK16108230 A HK 16108230A HK 1220234 A1 HK1220234 A1 HK 1220234A1
Authority
HK
Hong Kong
Prior art keywords
acceptors
donors
chemically modified
modified ligase
ligase cofactors
Prior art date
Application number
HK16108230.5A
Other languages
English (en)
Inventor
Natasha Paul
Sabrina Shore
Jonathan Shum
Alexandre Lebedev
Gerald Zon
Original Assignee
Trilink Biotechnologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trilink Biotechnologies Inc filed Critical Trilink Biotechnologies Inc
Publication of HK1220234A1 publication Critical patent/HK1220234A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/66—General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK16108230.5A 2013-03-15 2016-07-13 化學修飾的連接酶輔因子、供體和受體 HK1220234A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/833,600 US9631227B2 (en) 2009-07-06 2013-03-15 Chemically modified ligase cofactors, donors and acceptors
PCT/US2014/029612 WO2014144979A1 (en) 2013-03-15 2014-03-14 Chemically modified ligase cofactors, donors and acceptors

Publications (1)

Publication Number Publication Date
HK1220234A1 true HK1220234A1 (zh) 2017-04-28

Family

ID=51537845

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16108230.5A HK1220234A1 (zh) 2013-03-15 2016-07-13 化學修飾的連接酶輔因子、供體和受體

Country Status (10)

Country Link
US (2) US9631227B2 (zh)
EP (1) EP2971133A4 (zh)
JP (1) JP2016514460A (zh)
KR (1) KR20150132393A (zh)
CN (1) CN105308187A (zh)
AU (1) AU2014233457A1 (zh)
CA (1) CA2907146A1 (zh)
HK (1) HK1220234A1 (zh)
MX (1) MX2015013101A (zh)
WO (1) WO2014144979A1 (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2949759B1 (en) * 2014-05-27 2017-07-26 Université Paris Sud 11 Multiplexed homogeneous oligonucleotide detection
US10894979B2 (en) 2017-01-27 2021-01-19 Integrated Dna Technologies, Inc. Construction of next generation sequencing (NGS) libraries using competitive strand displacement
EP3573646B1 (en) * 2017-01-27 2022-02-23 Integrated DNA Technologies, Inc. Construction of next generation sequencing (ngs) libraries using competitive strand displacement
WO2019195701A1 (en) * 2018-04-05 2019-10-10 Massachusetts Eye And Ear Infirmary Methods of making and using combinatorial barcoded nucleic acid libraries having defined variation
EP3802864A1 (en) 2018-06-06 2021-04-14 The Regents Of The University Of California Methods of producing nucleic acid libraries and compositions and kits for practicing same
GB202007970D0 (en) * 2020-05-28 2020-07-15 Cambridge Entpr Ltd Method
DE102020216120A1 (de) 2020-12-17 2022-06-23 Robert Bosch Gesellschaft mit beschränkter Haftung Ermittlung der Quantität und Qualität einer DNA-Bibliothek

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5593826A (en) 1993-03-22 1997-01-14 Perkin-Elmer Corporation, Applied Biosystems, Inc. Enzymatic ligation of 3'amino-substituted oligonucleotides
US5508179A (en) 1994-03-18 1996-04-16 Bio-Rad Laboratories, Inc. Use of deoxyribose nicotinamide adenine dinucleotide to enhance the specificity of NAD+ -dependent ligation reactions
US5935788A (en) 1996-06-25 1999-08-10 Lifespan Biosciences, Inc. Subtractive hybridization techniques for identifying differentially expressed and commonly expressed nucleic acid
US6312892B1 (en) 1996-07-19 2001-11-06 Cornell Research Foundation, Inc. High fidelity detection of nucleic acid differences by ligase detection reaction
US6110710A (en) 1996-10-15 2000-08-29 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Sequence modification of oligonucleotide primers to manipulate non-templated nucleotide addition
US6949370B1 (en) 1998-10-30 2005-09-27 Cornell Research Foundation, Inc. High fidelity thermostable ligase and uses thereof
EP1163251A1 (en) 1999-03-24 2001-12-19 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES N-acylphosphoramidites and their use in oligonucleotide synthesis
US6297016B1 (en) 1999-10-08 2001-10-02 Applera Corporation Template-dependent ligation with PNA-DNA chimeric probes
CA2421057A1 (en) 2000-08-21 2002-02-28 Invitrogen Corporation Methods and reagents for molecular cloning
US6635425B2 (en) 2001-01-05 2003-10-21 Molecular Staging, Inc. 5′-thio phosphate directed ligation of oligonucleotides and use in detection of single nucleotide polymorphisms
AU2002312588A1 (en) 2001-06-29 2003-03-03 Rubicon Genomics Inc. Methods of using nick translate libraries for snp analysis
FR2852605B1 (fr) 2003-03-18 2012-11-30 Commissariat Energie Atomique Procede de preparation de fragments d'adn et ses applications
US8808991B2 (en) 2003-09-02 2014-08-19 Keygene N.V. Ola-based methods for the detection of target nucleic avid sequences
US20070031865A1 (en) 2005-07-07 2007-02-08 David Willoughby Novel Process for Construction of a DNA Library
JP5903379B2 (ja) * 2009-07-06 2016-04-13 トリリンク バイオテクノロジーズ インコーポレイテッド 化学修飾リガーゼ補因子、ドナーおよびアクセプター
WO2012094343A1 (en) 2011-01-05 2012-07-12 Trilink Biotechnologies Chemically substituted thermosensitive probes and cofactors for hot start ligation

Also Published As

Publication number Publication date
AU2014233457A1 (en) 2015-10-08
EP2971133A1 (en) 2016-01-20
US20140323354A1 (en) 2014-10-30
CN105308187A (zh) 2016-02-03
EP2971133A4 (en) 2016-11-30
MX2015013101A (es) 2016-05-05
JP2016514460A (ja) 2016-05-23
KR20150132393A (ko) 2015-11-25
CA2907146A1 (en) 2014-09-18
US9631227B2 (en) 2017-04-25
WO2014144979A1 (en) 2014-09-18
US20170275672A1 (en) 2017-09-28

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