HK1210805A1 - 重組草酸鹽降解酶的純化和分離以及含有草酸鹽降解酶的噴霧乾燥粒子 - Google Patents

重組草酸鹽降解酶的純化和分離以及含有草酸鹽降解酶的噴霧乾燥粒子

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Publication number
HK1210805A1
HK1210805A1 HK15111425.5A HK15111425A HK1210805A1 HK 1210805 A1 HK1210805 A1 HK 1210805A1 HK 15111425 A HK15111425 A HK 15111425A HK 1210805 A1 HK1210805 A1 HK 1210805A1
Authority
HK
Hong Kong
Prior art keywords
degrading enzymes
oxalate degrading
isolation
purification
spray
Prior art date
Application number
HK15111425.5A
Other languages
English (en)
Inventor
哈密特‧司杜
李青山
阿隆‧布萊克‧科里
卡爾-古斯塔夫‧格蘭德
Original Assignee
Oxthera Intellectual Property Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP09164430.2A external-priority patent/EP2270138B1/en
Priority claimed from US12/497,275 external-priority patent/US8431122B2/en
Application filed by Oxthera Intellectual Property Ab filed Critical Oxthera Intellectual Property Ab
Publication of HK1210805A1 publication Critical patent/HK1210805A1/zh

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/13Transferases (2.) transferring sulfur containing groups (2.8)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/04Drugs for disorders of the urinary system for urolithiasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0008Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK15111425.5A 2009-07-02 2015-11-19 重組草酸鹽降解酶的純化和分離以及含有草酸鹽降解酶的噴霧乾燥粒子 HK1210805A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09164430.2A EP2270138B1 (en) 2009-07-02 2009-07-02 Purification and isolation of recombinant oxalate degrading enzymes
US12/497,275 US8431122B2 (en) 2009-07-02 2009-07-02 Purification and isolation of recombinant oxalate degrading enzymes and spray-dried particles containing oxalate degrading enzymes
CN201080029636.9A CN102597225B (zh) 2009-07-02 2010-07-01 重组草酸盐降解酶的纯化和分离以及含有草酸盐降解酶的喷雾干燥粒子

Publications (1)

Publication Number Publication Date
HK1210805A1 true HK1210805A1 (zh) 2016-05-06

Family

ID=43028177

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15111425.5A HK1210805A1 (zh) 2009-07-02 2015-11-19 重組草酸鹽降解酶的純化和分離以及含有草酸鹽降解酶的噴霧乾燥粒子

Country Status (16)

Country Link
US (1) US20120189604A1 (zh)
EP (1) EP2449098B1 (zh)
JP (2) JP2012531186A (zh)
CN (2) CN102597225B (zh)
BR (1) BRPI1013956B8 (zh)
CA (2) CA2767039C (zh)
DK (1) DK2449098T3 (zh)
ES (1) ES2617917T3 (zh)
HK (1) HK1210805A1 (zh)
HU (1) HUE030905T2 (zh)
IL (1) IL216873A (zh)
IN (1) IN2012DN00592A (zh)
LT (1) LT2449098T (zh)
PL (1) PL2449098T3 (zh)
PT (1) PT2449098T (zh)
WO (1) WO2011000523A1 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8431122B2 (en) 2009-07-02 2013-04-30 Oxthera Intellectual Property Ab Purification and isolation of recombinant oxalate degrading enzymes and spray-dried particles containing oxalate degrading enzymes
US9714456B2 (en) * 2013-01-18 2017-07-25 Allena Pharmaceuticals, Inc. Crystallized oxalate decarboxylase and methods of use
CN103540569A (zh) * 2013-06-05 2014-01-29 黄虹寓 结石酶及其制备方法
EP3003358B1 (en) * 2013-06-07 2021-03-24 Allena Pharmaceuticals Inc. Compositions and devices for dialysis
CN107254453B (zh) * 2014-12-22 2019-10-25 武汉康复得生物科技股份有限公司 一种在生理pH条件下有活力的草酸氧化酶及其应用
CN116124853B (zh) * 2022-11-07 2024-01-16 东北农业大学 一种检测草酸的电化学生物传感器、制备方法及应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8486389B2 (en) * 1997-05-23 2013-07-16 Oxthera, Inc. Compositions and methods for treating or preventing oxalate-related disease
WO2004018634A2 (en) * 2002-08-20 2004-03-04 University Of Florida Polynucleotide encoding oxalate decarboxylase from aspergillus niger and methods of use
US6929940B1 (en) * 2002-08-20 2005-08-16 University Of Florida Research Foundation, Inc. Polynucleotides encoding oxalate decarboxylase from Aspergillus niger and methods of use
PT1962873E (pt) * 2005-12-14 2013-08-29 Oxthera Inc Composições farmacêuticas compreendendo bactérias redutoras de oxalato
ES2362897T3 (es) * 2005-12-16 2011-07-14 Oxthera, Inc. Composiciones y métodos para reducción del oxalato.
WO2008105911A2 (en) * 2006-08-02 2008-09-04 Altus Pharmaceuticals Inc. Crystallized oxalate decarboxylase and methods of use

Also Published As

Publication number Publication date
DK2449098T3 (en) 2017-03-06
US20120189604A1 (en) 2012-07-26
IN2012DN00592A (zh) 2015-06-12
CN104805067A (zh) 2015-07-29
JP6220845B2 (ja) 2017-10-25
CN102597225B (zh) 2015-04-29
CN102597225A (zh) 2012-07-18
HUE030905T2 (en) 2017-06-28
IL216873A (en) 2017-07-31
CA2767039A1 (en) 2011-01-06
BRPI1013956B1 (pt) 2021-04-06
PT2449098T (pt) 2017-03-10
EP2449098B1 (en) 2016-12-07
LT2449098T (lt) 2017-05-25
PL2449098T3 (pl) 2017-06-30
BRPI1013956A2 (pt) 2019-04-09
EP2449098A1 (en) 2012-05-09
CA3012811A1 (en) 2011-01-06
BRPI1013956B8 (pt) 2021-05-25
ES2617917T3 (es) 2017-06-20
JP2016121138A (ja) 2016-07-07
IL216873A0 (en) 2012-02-29
CA2767039C (en) 2018-09-04
JP2012531186A (ja) 2012-12-10
WO2011000523A1 (en) 2011-01-06

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