HK1130258A1 - 用於抑制組織蛋白去乙酰酶的化合物 - Google Patents

用於抑制組織蛋白去乙酰酶的化合物

Info

Publication number
HK1130258A1
HK1130258A1 HK09109348.1A HK09109348A HK1130258A1 HK 1130258 A1 HK1130258 A1 HK 1130258A1 HK 09109348 A HK09109348 A HK 09109348A HK 1130258 A1 HK1130258 A1 HK 1130258A1
Authority
HK
Hong Kong
Prior art keywords
inhibition
compounds
histone deacetylase
deacetylase
histone
Prior art date
Application number
HK09109348.1A
Other languages
English (en)
Inventor
黃中洋
陳嘉南
黃偉展
黃致翔
紀俐伶
游秋萍
Original Assignee
彥臣生技藥品股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 彥臣生技藥品股份有限公司 filed Critical 彥臣生技藥品股份有限公司
Publication of HK1130258A1 publication Critical patent/HK1130258A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/20—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 hydrogenated in the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK09109348.1A 2007-09-14 2009-10-08 用於抑制組織蛋白去乙酰酶的化合物 HK1130258A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07116430.5A EP2045247B1 (en) 2007-09-14 2007-09-14 Compounds for the inhibition of histone deacetylase

Publications (1)

Publication Number Publication Date
HK1130258A1 true HK1130258A1 (zh) 2009-12-24

Family

ID=40352366

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09109348.1A HK1130258A1 (zh) 2007-09-14 2009-10-08 用於抑制組織蛋白去乙酰酶的化合物

Country Status (4)

Country Link
EP (1) EP2045247B1 (zh)
ES (1) ES2539828T3 (zh)
HK (1) HK1130258A1 (zh)
PT (1) PT2045247E (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9914722B2 (en) 2012-03-23 2018-03-13 Ptc Therapeutics, Inc. Compounds for treating spinal muscular atrophy
FR3125047B1 (fr) * 2021-07-06 2024-03-15 Centre Nat Rech Scient Composé de type 7a,8,9,10,11,11a-hexahydro-1H,7H-pyrano[2,3-c]xanthene, leur procédé de préparation, leurs intermédiaires et leurs applications thérapeutiques.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE529418T1 (de) * 2003-06-20 2011-11-15 Pokka Corp Flavanonverbindung und deren verwendungen

Also Published As

Publication number Publication date
PT2045247E (pt) 2015-06-09
EP2045247A1 (en) 2009-04-08
EP2045247B1 (en) 2015-04-08
ES2539828T3 (es) 2015-07-06

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