HK1088243A1 - Composition comprising active prourokinase, its freeze-drying process and lyophilized preparation - Google Patents

Composition comprising active prourokinase, its freeze-drying process and lyophilized preparation

Info

Publication number
HK1088243A1
HK1088243A1 HK06108807.0A HK06108807A HK1088243A1 HK 1088243 A1 HK1088243 A1 HK 1088243A1 HK 06108807 A HK06108807 A HK 06108807A HK 1088243 A1 HK1088243 A1 HK 1088243A1
Authority
HK
Hong Kong
Prior art keywords
prourokinase
freeze
active
composition
drying process
Prior art date
Application number
HK06108807.0A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of HK1088243A1 publication Critical patent/HK1088243A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49—Urokinase; Tissue plasminogen activator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
HK06108807.0A 2004-08-06 2006-08-08 Composition comprising active prourokinase, its freeze-drying process and lyophilized preparation HK1088243A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNB2004100580060A CN100420485C (en) 2004-08-06 2004-08-06 Composition containing active prourokinase, freeze-drying process and freeze-dried preparation thereof

Publications (1)

Publication Number Publication Date
HK1088243A1 true HK1088243A1 (en) 2006-11-03

Family

ID=35786873

Family Applications (1)

Application Number Title Priority Date Filing Date
HK06108807.0A HK1088243A1 (en) 2004-08-06 2006-08-08 Composition comprising active prourokinase, its freeze-drying process and lyophilized preparation

Country Status (3)

Country Link
CN (1) CN100420485C (en)
HK (1) HK1088243A1 (en)
WO (1) WO2006012791A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104906054B (en) * 2015-06-15 2017-08-25 武汉人福药业有限责任公司 A kind of freeze-dried preparation method of urokinase
CN110151705A (en) * 2018-02-13 2019-08-23 天士力生物医药股份有限公司 The freeze drying process of injection recombinant human urokinase zymogen
CN110339349A (en) * 2018-04-04 2019-10-18 天士力生物医药股份有限公司 A kind of recombinant human urokinase zymogen composition and preparation method thereof
CN113116831A (en) * 2019-12-26 2021-07-16 天士力生物医药股份有限公司 Freeze-drying method of recombinant human prourokinase for injection
CN114191385B (en) * 2021-12-22 2023-06-30 天士力生物医药股份有限公司 Recombinant human urokinase original injection and preparation method thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8809093D0 (en) * 1988-04-18 1988-05-18 Erba Carlo Spa Low molecular weight derivatives of prourokinase
CN1062016C (en) * 1996-09-27 2001-02-14 中国人民解放军军事医学科学院生物工程研究所 Preparation of reorganized human saccharified urokinasen
CN1311076C (en) * 2003-04-16 2007-04-18 普罗特奥姆技术公司 Method for producing recombinaton urokinase

Also Published As

Publication number Publication date
CN100420485C (en) 2008-09-24
CN1730098A (en) 2006-02-08
WO2006012791A1 (en) 2006-02-09

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