HK1073994A1 - Method for producing an active ingredient concentrate, and active ingredient concentrate - Google Patents
Method for producing an active ingredient concentrate, and active ingredient concentrateInfo
- Publication number
- HK1073994A1 HK1073994A1 HK05103936A HK05103936A HK1073994A1 HK 1073994 A1 HK1073994 A1 HK 1073994A1 HK 05103936 A HK05103936 A HK 05103936A HK 05103936 A HK05103936 A HK 05103936A HK 1073994 A1 HK1073994 A1 HK 1073994A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- active ingredient
- ingredient concentrate
- producing
- water
- concentrate
- Prior art date
Links
- 239000004480 active ingredient Substances 0.000 title 2
- 239000012141 concentrate Substances 0.000 title 2
- 238000004519 manufacturing process Methods 0.000 title 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- 229940087168 alpha tocopherol Drugs 0.000 abstract 1
- AGBQKNBQESQNJD-UHFFFAOYSA-M lipoate Chemical compound [O-]C(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-M 0.000 abstract 1
- 235000019136 lipoic acid Nutrition 0.000 abstract 1
- 235000020660 omega-3 fatty acid Nutrition 0.000 abstract 1
- 229940012843 omega-3 fatty acid Drugs 0.000 abstract 1
- 239000006014 omega-3 oil Substances 0.000 abstract 1
- 239000004550 soluble concentrate Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 229960002663 thioctic acid Drugs 0.000 abstract 1
- 229960000984 tocofersolan Drugs 0.000 abstract 1
- 239000002076 α-tocopherol Substances 0.000 abstract 1
- 235000004835 α-tocopherol Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
- A23L33/11—Plant sterols or derivatives thereof, e.g. phytosterols
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A23L33/12—Fatty acids or derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Saccharide Compounds (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10109708A DE10109708A1 (de) | 2001-02-11 | 2001-02-11 | Wasserlösliches Wirkstoffkonzentrat |
DE10108614A DE10108614B4 (de) | 2001-02-22 | 2001-02-22 | Wasserlösliches Konzentrat eines stoffwechselbeeinflussenden Wirkstoffes |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1073994A1 true HK1073994A1 (en) | 2005-10-28 |
Family
ID=26008603
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK05103936A HK1073994A1 (en) | 2001-02-11 | 2005-05-10 | Method for producing an active ingredient concentrate, and active ingredient concentrate |
Country Status (11)
Country | Link |
---|---|
US (1) | US20040081670A1 (xx) |
EP (3) | EP1377273B1 (xx) |
JP (2) | JP2004531530A (xx) |
AT (2) | ATE425743T1 (xx) |
AU (1) | AU2002250914A1 (xx) |
CA (1) | CA2436273A1 (xx) |
DE (2) | DE50213362D1 (xx) |
ES (1) | ES2324400T3 (xx) |
HK (1) | HK1073994A1 (xx) |
MX (1) | MXPA03007141A (xx) |
WO (1) | WO2002085328A2 (xx) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1377273B1 (de) * | 2001-02-11 | 2009-03-18 | Aquanova Ag | Verfahren zur herstellung eines isoflavon-konzentrats |
AU2002328824A1 (en) * | 2002-06-29 | 2004-01-19 | Aquanova German Solubilisate Technologies (Agt) Gmbh | Isoflavone concentrate and method for production thereof |
DE10306177A1 (de) * | 2003-02-13 | 2004-09-02 | Aquanova German Solubilisate Technologies (Agt) | Wirkstoffkonzentrate |
DE20319249U1 (de) * | 2003-12-10 | 2004-12-30 | Aquanova German Solubilisate Technologies (Agt) Gmbh | Lutein-Konzentrat |
JP2008506725A (ja) * | 2004-07-22 | 2008-03-06 | アクヴァノヴァ・ジャーマン・ソリュービリセイト・テクノロジーズ・(アーゲーテー)・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | エッセンシャルオイルおよび他の物質の可溶化産物 |
EP1781119B1 (de) * | 2004-08-18 | 2010-01-27 | Aquanova AG | Liponsäure-konzentrat |
EP1814412A1 (en) * | 2004-09-27 | 2007-08-08 | Nestec S.A. | Skin care beverage composition |
US20080220102A1 (en) * | 2005-07-08 | 2008-09-11 | Dariush Behnam | Solubilsation Products of an Active Ingredient Extract |
DE102006024911A1 (de) * | 2006-05-24 | 2007-11-29 | Aquanova Ag | Boswellinsäure-Konzentrat |
JP2007016000A (ja) * | 2005-07-11 | 2007-01-25 | Taiyo Kagaku Co Ltd | チオクト酸含有組成物 |
JP5031777B2 (ja) * | 2006-03-07 | 2012-09-26 | ツェットエーアー・ベタイリグングスゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 保存剤の可溶化物およびそれらの製造方法 |
ATE553748T1 (de) * | 2006-09-22 | 2012-05-15 | Mivital Ag | Emulsionen enthaltend gummi arabicum |
EP2241314B1 (en) * | 2007-12-14 | 2013-04-17 | Ezaki Glico Co., Ltd. | Alpha-lipoic acid nanoparticle and method for producing the same |
ES2661812T3 (es) * | 2009-10-16 | 2018-04-04 | Mochida Pharmaceutical Co., Ltd. | Composiciones |
US8637569B2 (en) | 2009-10-22 | 2014-01-28 | Api Genesis, Llc | Methods of increasing solubility of poorly soluble compounds and methods of making and using formulations of such compounds |
CN102711743A (zh) | 2009-10-22 | 2012-10-03 | Api起源有限责任公司 | 含有黄酮类的组合物的制备和使用方法 |
CA2791693C (en) | 2010-03-12 | 2018-11-27 | Niven Rajin Narain | Intravenous formulations of coenzyme q10 (coq10) and methods of use thereof |
EP3345594B1 (en) * | 2010-10-22 | 2021-11-17 | Technology Investments LC | Solubilized flavonoid composition |
MX369543B (es) | 2011-06-17 | 2019-11-12 | Berg Llc | Composiciones farmaceuticas inhalables. |
DE102012103767A1 (de) * | 2012-04-27 | 2013-10-31 | Chemische Fabrik Budenheim Kg | Antimikrobielles Mittel |
DE202012012130U1 (de) * | 2012-12-19 | 2014-03-21 | Aquanova Ag | Curcuminsolubilisat |
JP7063558B2 (ja) * | 2017-08-03 | 2022-05-09 | 花王株式会社 | 膜構造体の製造方法 |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3052608A (en) * | 1959-05-07 | 1962-09-04 | Joseph J Hirsh | Lanolin transparent emulsions |
US3390098A (en) * | 1964-06-08 | 1968-06-25 | Armour Pharma | Antioxidant composition |
US4146499A (en) * | 1976-09-18 | 1979-03-27 | Rosano Henri L | Method for preparing microemulsions |
DE3048000A1 (de) * | 1980-12-19 | 1982-07-15 | Basf Ag | Stabile injizierbare (beta)-carotin-solubilisate und verfahren zu ihrer herstellung |
JP2565513B2 (ja) * | 1987-09-25 | 1996-12-18 | 三省製薬株式会社 | メラニン生成抑制外用薬剤 |
JPH03165833A (ja) * | 1989-02-28 | 1991-07-17 | Isamu Horikoshi | 新規懸濁化方法及びこの方法によって得られる組成物 |
CA2010894A1 (en) * | 1989-02-28 | 1990-08-31 | Isamu Horikoshi | Method of forming a suspension and composition formed by said method |
PT95826B (pt) * | 1989-11-09 | 1997-11-28 | Asta Medica Ag | Processo para a preparacao de composicoes farmaceuticas contendo como ingrediente activo acido r-alfa-liponico ou acido s-alfa-liponico |
DE4038385C2 (de) * | 1990-12-01 | 1998-09-17 | Hoyer Gmbh & Co Kg | Sitosterol und seine Glykoside mit verbesserter Bioverfügbarkeit |
US5569670A (en) * | 1992-06-05 | 1996-10-29 | Asta Medica Aktiengesellschaft | Combination medications containing alpha-lipoic acid and related |
CH685325A5 (de) * | 1994-01-04 | 1995-06-15 | Marigen Sa | Ultramikroemulsionen aus spontan dispergierbaren Konzentraten mit schwer löslichen Carotinen. |
CA2186034C (en) * | 1994-03-22 | 2002-11-26 | Michael E. Hrinda | Highly efficient production and isolation of viral particles |
WO1997010814A1 (en) * | 1995-09-18 | 1997-03-27 | Vesifact Ag | Propofol nanodispersions |
ATE257698T1 (de) * | 1996-10-03 | 2004-01-15 | Hermes Biosciences Inc | Hydrophile mikropartikel und verfahren zu deren herstellung |
DE19647352C2 (de) * | 1996-11-15 | 2000-06-29 | Aqua Nova Getraenketechnologie | Nicht alkoholisches Getränk mit einem Gehalt an Q 10 |
EP1039893B1 (en) * | 1997-12-10 | 2011-02-02 | Cyclosporine Therapeutics Limited | Pharmaceutical compositions containing an omega-3 fatty acid oil |
WO1999038509A1 (en) * | 1998-01-28 | 1999-08-05 | Dusan Miljkovic | Isoflavanoid formulations for oral administration |
JP3335307B2 (ja) * | 1998-03-19 | 2002-10-15 | 株式会社東芝 | ソルダーペースト及びハンダ接合形成用フラックス |
AU3843999A (en) * | 1998-05-07 | 1999-11-23 | Elan Corporation, Plc | Solvent/cosolvent free microemulsion and emulsion preconcentrate drug delivery systems |
EP0956779A1 (de) * | 1998-05-11 | 1999-11-17 | Vesifact Ag | Nahrungsmittel, welche wasserunlösliche Komponenten enthalten |
US6197340B1 (en) * | 1998-05-28 | 2001-03-06 | Medical Research Institute | Controlled release lipoic acid |
AU7638300A (en) * | 1999-10-20 | 2001-04-30 | Vesifact Ag | Microemulsion preconcentrates and microemulsions |
US6664287B2 (en) * | 2000-03-15 | 2003-12-16 | Bethesda Pharmaceuticals, Inc. | Antioxidants |
DE10104847B4 (de) * | 2000-06-09 | 2006-12-21 | Aquanova German Solubilisate Technologies (Agt) Gmbh | Tocopherol-Konzentrat und Verfahren zu seiner Herstellung |
DE10103454A1 (de) * | 2000-12-29 | 2002-08-01 | Aquanova Getraenketechnologie | Wirkstoffkonzentrate sowie Verfahren zu ihrer Herstellung |
EP1377273B1 (de) * | 2001-02-11 | 2009-03-18 | Aquanova Ag | Verfahren zur herstellung eines isoflavon-konzentrats |
-
2002
- 2002-02-11 EP EP02719799A patent/EP1377273B1/de not_active Expired - Lifetime
- 2002-02-11 WO PCT/EP2002/001416 patent/WO2002085328A2/de active Application Filing
- 2002-02-11 DE DE50213362T patent/DE50213362D1/de not_active Expired - Lifetime
- 2002-02-11 DE DE50211435T patent/DE50211435D1/de not_active Expired - Lifetime
- 2002-02-11 AT AT02719799T patent/ATE425743T1/de active
- 2002-02-11 EP EP05027278A patent/EP1645267A3/de not_active Withdrawn
- 2002-02-11 ES ES02719799T patent/ES2324400T3/es not_active Expired - Lifetime
- 2002-02-11 AU AU2002250914A patent/AU2002250914A1/en not_active Abandoned
- 2002-02-11 EP EP04010510A patent/EP1475083B1/de not_active Expired - Lifetime
- 2002-02-11 US US10/470,749 patent/US20040081670A1/en not_active Abandoned
- 2002-02-11 AT AT04010510T patent/ATE381923T1/de active
- 2002-02-11 CA CA002436273A patent/CA2436273A1/en not_active Abandoned
- 2002-02-11 JP JP2002582902A patent/JP2004531530A/ja active Pending
- 2002-02-11 MX MXPA03007141A patent/MXPA03007141A/es active IP Right Grant
-
2005
- 2005-05-10 HK HK05103936A patent/HK1073994A1/xx not_active IP Right Cessation
-
2006
- 2006-04-19 JP JP2006115962A patent/JP2006241167A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DE50211435D1 (de) | 2008-02-07 |
ATE425743T1 (de) | 2009-04-15 |
EP1377273A2 (de) | 2004-01-07 |
ES2324400T3 (es) | 2009-08-06 |
JP2004531530A (ja) | 2004-10-14 |
JP2006241167A (ja) | 2006-09-14 |
WO2002085328A3 (de) | 2003-11-06 |
DE50213362D1 (de) | 2009-04-30 |
ATE381923T1 (de) | 2008-01-15 |
EP1645267A2 (de) | 2006-04-12 |
EP1475083A1 (de) | 2004-11-10 |
WO2002085328A2 (de) | 2002-10-31 |
EP1475083B1 (de) | 2007-12-26 |
CA2436273A1 (en) | 2002-10-31 |
MXPA03007141A (es) | 2003-11-18 |
EP1377273B1 (de) | 2009-03-18 |
EP1645267A3 (de) | 2007-10-10 |
US20040081670A1 (en) | 2004-04-29 |
AU2002250914A1 (en) | 2002-11-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PE | Patent expired |
Effective date: 20220214 |