HK1073844A1 - Method for the production and purification of 1,7' - dimethyl - 2'- propyl - 2,5'- bi-1h-benzimidazole - Google Patents

Method for the production and purification of 1,7' - dimethyl - 2'- propyl - 2,5'- bi-1h-benzimidazole

Info

Publication number
HK1073844A1
HK1073844A1 HK05106433.7A HK05106433A HK1073844A1 HK 1073844 A1 HK1073844 A1 HK 1073844A1 HK 05106433 A HK05106433 A HK 05106433A HK 1073844 A1 HK1073844 A1 HK 1073844A1
Authority
HK
Hong Kong
Prior art keywords
benzimidazole
propyl
dimethyl
purification
production
Prior art date
Application number
HK05106433.7A
Other languages
English (en)
Inventor
Werner Belzer
Rolf Dach
Volker Fachinger
Markus Heitzmann
Hartmut Schmidt
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7712431&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1073844(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of HK1073844A1 publication Critical patent/HK1073844A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK05106433.7A 2002-01-18 2005-07-27 Method for the production and purification of 1,7' - dimethyl - 2'- propyl - 2,5'- bi-1h-benzimidazole HK1073844A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10201725A DE10201725A1 (de) 2002-01-18 2002-01-18 Verfahren zur Herstellung und Reinigung von 1,7'-Dimethyl-2'-propyl-2,5'-bi-1H-benzimidazol
PCT/EP2003/000319 WO2003059890A1 (de) 2002-01-18 2003-01-15 Verfahren zur herstellung und reinigung von 1,7'-dimethyl-2'-propyl-2,5'-bi-1h-benzimidazol

Publications (1)

Publication Number Publication Date
HK1073844A1 true HK1073844A1 (en) 2005-10-21

Family

ID=7712431

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05106433.7A HK1073844A1 (en) 2002-01-18 2005-07-27 Method for the production and purification of 1,7' - dimethyl - 2'- propyl - 2,5'- bi-1h-benzimidazole

Country Status (10)

Country Link
EP (2) EP2199286A1 (xx)
JP (2) JP5129918B2 (xx)
CN (1) CN100436426C (xx)
AT (1) ATE465998T1 (xx)
AU (1) AU2003235720A1 (xx)
CA (1) CA2471730C (xx)
DE (2) DE10201725A1 (xx)
ES (1) ES2341235T3 (xx)
HK (1) HK1073844A1 (xx)
WO (1) WO2003059890A1 (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2414019A (en) * 2004-05-11 2005-11-16 Cipla Ltd One-step preparation of telmisartan by condensation and hydrolysis
US7943781B2 (en) 2004-10-18 2011-05-17 Dr. Reddy's Laboratories Limited Process for preparing telmisartan
DE102005034279A1 (de) 2005-07-22 2007-01-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Herstellung von 1,7'-Dimethyl-2'-propyl-2,5'-bi-1H-benzimidazol
CN101172968B (zh) * 2006-11-01 2010-05-12 浙江天宇药业有限公司 2-正丙基-4甲基-6-(甲基苯并咪唑-2-基)苯并咪唑盐及其制备方法
JP2011519840A (ja) * 2008-05-02 2011-07-14 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング １，７’−ジメチル−２’−プロピル−２，５’−ビ−１ｈ−ベンゾイミダゾールの製造
CN101717370A (zh) * 2009-11-30 2010-06-02 常州亚邦制药有限公司 一种制备2-正丙基-4-甲基-6-(1-甲基苯并咪唑-2-基)苯并咪唑的新方法
JP6210599B2 (ja) * 2014-02-26 2017-10-11 株式会社トクヤマ ４−メチル−６（１−メチルベンズイミダゾール−２−イル）−２−ｎ−プロピル−１Ｈ−ベンズイミダゾールの製造方法
CN104974096B (zh) * 2015-07-07 2019-02-01 威海迪素制药有限公司 一种替米沙坦中间体的制备方法
CN107434786A (zh) * 2016-05-27 2017-12-05 广东东阳光药业有限公司 苯并咪唑化合物及其制备方法
US11053203B2 (en) 2017-11-13 2021-07-06 Ecolab Usa Inc. One-pot homogeneous process for the large scale manufacture of 2-substituted benzimidazoles
CN111808027A (zh) * 2020-05-25 2020-10-23 重庆康刻尔制药有限公司 一种替米沙坦中间体的纯化方法
CN115466222B (zh) * 2022-07-28 2024-06-04 江苏中邦制药有限公司 一种替米沙坦中间体的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1225318B (de) * 1959-09-05 1966-09-22 Bayer Ag Verfahren zur Herstellung von Azofarbstoffen und deren Metallkomplexverbindungen
DE19917524C2 (de) 1999-04-17 2001-09-20 Boehringer Ingelheim Pharma Verfahren zur Nitrierung von Anilinderivaten

Also Published As

Publication number Publication date
ATE465998T1 (de) 2010-05-15
DE10201725A1 (de) 2003-08-14
CA2471730A1 (en) 2003-07-24
CN100436426C (zh) 2008-11-26
EP2199286A1 (de) 2010-06-23
WO2003059890A1 (de) 2003-07-24
EP1470111A1 (de) 2004-10-27
EP1470111B1 (de) 2010-04-28
AU2003235720A1 (en) 2003-07-30
CA2471730C (en) 2011-03-29
DE50312660D1 (de) 2010-06-10
JP5129918B2 (ja) 2013-01-30
ES2341235T3 (es) 2010-06-17
JP2010241839A (ja) 2010-10-28
JP2005529064A (ja) 2005-09-29
CN1620437A (zh) 2005-05-25

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20160115