HK1061700A1 - An assay for detecting inhibitors of the enzyme myeloperokidase - Google Patents

An assay for detecting inhibitors of the enzyme myeloperokidase

Info

Publication number
HK1061700A1
HK1061700A1 HK04104619A HK04104619A HK1061700A1 HK 1061700 A1 HK1061700 A1 HK 1061700A1 HK 04104619 A HK04104619 A HK 04104619A HK 04104619 A HK04104619 A HK 04104619A HK 1061700 A1 HK1061700 A1 HK 1061700A1
Authority
HK
Hong Kong
Prior art keywords
myeloperokidase
assay
enzyme
detecting inhibitors
inhibitors
Prior art date
Application number
HK04104619A
Other languages
English (en)
Inventor
Anthony Kettle
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/SE2001/001014 external-priority patent/WO2001085146A1/en
Priority claimed from PCT/SE2002/000877 external-priority patent/WO2002090575A1/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of HK1061700A1 publication Critical patent/HK1061700A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0065Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
HK04104619A 2001-05-08 2004-06-28 An assay for detecting inhibitors of the enzyme myeloperokidase HK1061700A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/SE2001/001014 WO2001085146A1 (en) 2000-05-12 2001-05-08 Pharmaceutical compounds for treating copd
SE0103766A SE0103766D0 (sv) 2001-11-09 2001-11-09 Novel assay
PCT/SE2002/000877 WO2002090575A1 (en) 2001-05-08 2002-05-06 An assay for detecting inhibitors of the enzyme mueloperokidase

Publications (1)

Publication Number Publication Date
HK1061700A1 true HK1061700A1 (en) 2004-09-30

Family

ID=20285957

Family Applications (1)

Application Number Title Priority Date Filing Date
HK04104619A HK1061700A1 (en) 2001-05-08 2004-06-28 An assay for detecting inhibitors of the enzyme myeloperokidase

Country Status (10)

Country Link
US (1) US7108997B2 (no)
KR (1) KR100879700B1 (no)
BR (1) BR0209446A (no)
CY (1) CY1107345T1 (no)
HK (1) HK1061700A1 (no)
MX (1) MXPA03010143A (no)
NO (1) NO20034951D0 (no)
PT (1) PT1387893E (no)
SE (1) SE0103766D0 (no)
ZA (1) ZA200308185B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR039385A1 (es) * 2002-04-19 2005-02-16 Astrazeneca Ab Derivados de tioxantina como inhibidores de la mieloperoxidasa
SE0302756D0 (sv) * 2003-10-17 2003-10-17 Astrazeneca Ab Novel Compounds
SE0402591D0 (sv) * 2004-10-25 2004-10-25 Astrazeneca Ab Novel use
MY140748A (en) * 2004-12-06 2010-01-15 Astrazeneca Ab Novel pyrrolo [3,2-d] pyrimidin-4-one derivatives and their use in therapy
TW200804383A (en) * 2006-06-05 2008-01-16 Astrazeneca Ab New compounds
WO2011133581A1 (en) 2010-04-19 2011-10-27 General Atomics Methods and compositions for assaying enzymatic activity of myeloperoxidase in blood samples
CA2839747A1 (en) 2011-07-11 2013-01-17 Exoxemis, Inc. Eosinophil peroxidase compositions and methods of their use
US20150099010A1 (en) 2013-10-07 2015-04-09 Reoxcyn Discoveries Group, Inc Redox signaling gel formulation
WO2017127452A1 (en) 2016-01-19 2017-07-27 Reoxcyn Discoveries Group, Inc. Hypochlorite formulations for wound healing
US11857674B2 (en) 2016-05-18 2024-01-02 Reoxcyn, Llc Lubricant formulations
US9474768B1 (en) 2016-05-18 2016-10-25 Reoxcyn Discoveries Group, Inc. Lubricant formulations
US9833471B1 (en) 2016-09-15 2017-12-05 Reoxcyn Discoveries Group, Inc. Hypochlorous acid-based hand sanitizer
US20180200165A1 (en) 2017-01-16 2018-07-19 Reoxcyn Innovation Group, Llc Dentifrice formulations and methods of oral care

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6046019A (en) * 1991-07-09 2000-04-04 Goumeniouk; Alexander P. Diagnostic kits and methods for making granulocyte cell counts
US5976823A (en) 1997-03-19 1999-11-02 Integrated Biomedical Technology, Inc. Low range total available chlorine test strip
GB2362101A (en) * 2000-05-12 2001-11-14 Astrazeneca Ab Treatment of chronic obstructive pulmonary disease
FR2819723B1 (fr) * 2001-01-23 2006-11-17 Arnaud Mainnemare Composition halogene, son procede de preparation et ses utilisations

Also Published As

Publication number Publication date
KR20030094389A (ko) 2003-12-11
ZA200308185B (en) 2004-07-05
PT1387893E (pt) 2007-02-28
BR0209446A (pt) 2004-08-03
NO20034951D0 (no) 2003-11-06
CY1107345T1 (el) 2012-12-19
MXPA03010143A (es) 2004-05-21
US7108997B2 (en) 2006-09-19
SE0103766D0 (sv) 2001-11-09
US20040142407A1 (en) 2004-07-22
KR100879700B1 (ko) 2009-01-21

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20110506