HK1040707A1 - Oxazolidinone antibacterial agents having a thiocarbonyl functionality - Google Patents

Oxazolidinone antibacterial agents having a thiocarbonyl functionality

Info

Publication number
HK1040707A1
HK1040707A1 HK02102339.4A HK02102339A HK1040707A1 HK 1040707 A1 HK1040707 A1 HK 1040707A1 HK 02102339 A HK02102339 A HK 02102339A HK 1040707 A1 HK1040707 A1 HK 1040707A1
Authority
HK
Hong Kong
Prior art keywords
antibacterial agents
oxazolidinone antibacterial
thiocarbonyl functionality
thiocarbonyl
functionality
Prior art date
Application number
HK02102339.4A
Other languages
Chinese (zh)
Inventor
J‧B‧小海斯特
E‧G‧尼迪
S‧C‧派裏克恩
T-J‧波爾
Original Assignee
法瑪西雅厄普約翰美國公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 法瑪西雅厄普約翰美國公司 filed Critical 法瑪西雅厄普約翰美國公司
Publication of HK1040707A1 publication Critical patent/HK1040707A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18Oxygen atoms
    • C07D263/20Oxygen atoms attached in position 2
    • C07D263/22Oxygen atoms attached in position 2 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to other ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK02102339.4A 1998-11-27 2002-03-27 Oxazolidinone antibacterial agents having a thiocarbonyl functionality HK1040707A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1998/025308 WO2000032599A1 (en) 1998-11-27 1998-11-27 Oxazolidinone antibacterial agents having a thiocarbonyl functionality

Publications (1)

Publication Number Publication Date
HK1040707A1 true HK1040707A1 (en) 2002-06-21

Family

ID=22268382

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02102339.4A HK1040707A1 (en) 1998-11-27 2002-03-27 Oxazolidinone antibacterial agents having a thiocarbonyl functionality

Country Status (8)

Country Link
EP (1) EP1133493A1 (en)
JP (1) JP2002531455A (en)
KR (1) KR20010107987A (en)
CN (1) CN1322204A (en)
AU (1) AU764980B2 (en)
CA (1) CA2351062A1 (en)
HK (1) HK1040707A1 (en)
WO (1) WO2000032599A1 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6297242B1 (en) * 1999-08-12 2001-10-02 Ortho-Mcneil Pharmaceutical, Inc. N-substituted amidine and guanidine oxazolidinone antibacterials and methods of use thereof
WO2003008389A1 (en) * 2001-07-16 2003-01-30 Ranbaxy Laboratories Limited Oxazolidinone derivatives as potential antimicrobials
PL363960A1 (en) * 2000-07-17 2004-11-29 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
WO2002032857A1 (en) * 2000-10-17 2002-04-25 Pharmacia & Upjohn Company Methods of producing oxazolidinone compounds
GB0108793D0 (en) * 2001-04-07 2001-05-30 Astrazeneca Ab Chemical compounds
US6956040B2 (en) 2001-07-16 2005-10-18 Ranbaxy Laboratories Limited Oxazolidinone piperazinyl derivatives as potential antimicrobials
WO2004018439A1 (en) * 2002-08-22 2004-03-04 Orchid Chemicals & Pharmaceuticals Ltd Novel antibacterial agents
AU2003215861A1 (en) * 2003-04-07 2004-11-01 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
US7265140B2 (en) * 2003-09-23 2007-09-04 Pfizer Inc Acyloxymethylcarbamate prodrugs of oxazolidinones
US20090247545A1 (en) * 2004-10-11 2009-10-01 Mukund Keshao Gurjar Substituted oxazolidinone derivatives
WO2006043121A1 (en) * 2004-10-20 2006-04-27 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
CA2589171A1 (en) * 2004-11-29 2006-06-01 Pharmacia & Upjohn Company Llc Thiazepine oxazolidinones as antibacterial agents
AU2006231919A1 (en) 2005-04-06 2006-10-12 Pharmacia & Upjohn Company Llc 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents
ATE449773T1 (en) 2005-06-29 2009-12-15 Pharmacia & Upjohn Co Llc HOMOMORPHOLINOXAZOLIDINONES AS ANTIBACTERIAL AGENTS
KR20070038236A (en) * 2005-10-05 2007-04-10 일동제약주식회사 A novel oxazolidinone formamide derivative and manufacturing process thereof
WO2007070506A2 (en) 2005-12-14 2007-06-21 Amgen Inc. Diaza heterocyclic sulfonamide derivatives and their uses
WO2007114326A1 (en) 2006-03-31 2007-10-11 Research Foundation Itsuu Laboratory Novel compound having heterocyclic ring
CA2692255A1 (en) * 2007-06-22 2008-12-31 Orchid Research Laboratories Limited Novel compounds and their use
EP2208729A4 (en) 2007-10-02 2011-04-27 Res Found Itsuu Lab Oxazolidinone derivative having 7-membered hetero ring
WO2012153155A1 (en) * 2011-05-06 2012-11-15 Egis Gyógyszergyár Nyilvãnosan Müködö Részvény-Társaság Process for the preparation of a rivaroxaban and intermediates formed in said process
US10550092B2 (en) * 2015-07-17 2020-02-04 The Global Alliance For Tb Drug Development, Inc. Substituted phenyloxazolidinones for antimicrobial therapy
WO2017066964A1 (en) * 2015-10-22 2017-04-27 Merck Sharp & Dohme Corp. Oxazolidinone compounds and methods of use thereof as antibacterial agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK283420B6 (en) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Oxazolidinones containing a substituted diazine moiety and their use as antimicrobials
MY115155A (en) * 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
JP2002501530A (en) * 1997-05-30 2002-01-15 ファルマシア・アンド・アップジョン・カンパニー Oxazolidinone antimicrobial agents with thiocarbonyl functionality
AU9001598A (en) * 1997-09-11 1999-03-29 Hokuriku Seiyaku Co. Ltd Thiourea derivatives

Also Published As

Publication number Publication date
CN1322204A (en) 2001-11-14
AU764980B2 (en) 2003-09-04
WO2000032599A1 (en) 2000-06-08
EP1133493A1 (en) 2001-09-19
KR20010107987A (en) 2001-12-07
AU1705399A (en) 2000-06-19
JP2002531455A (en) 2002-09-24
CA2351062A1 (en) 2000-06-08

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