HK1030881A1 - Masking agent in powder form for pharmaceutical flavours - Google Patents
Masking agent in powder form for pharmaceutical flavoursInfo
- Publication number
- HK1030881A1 HK1030881A1 HK01101524A HK01101524A HK1030881A1 HK 1030881 A1 HK1030881 A1 HK 1030881A1 HK 01101524 A HK01101524 A HK 01101524A HK 01101524 A HK01101524 A HK 01101524A HK 1030881 A1 HK1030881 A1 HK 1030881A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- pharmaceutical
- flavours
- flavoring
- taste
- mask
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Seasonings (AREA)
Abstract
A powdered agent to mask the taste of pharmaceutical compositions comprises a flavoring (I) and a potentiator (II) in the form of an intimate and essentially homogeneous mixture, the proportion of (I) and (II) in each particle of the mixture are constant. The flavoring (I) is preferably a sweetener, such as sodium or calcium saccharinates, saccharin, aspartyl-phenylalanine, acesulfame, cyclamates, and stevioside. The poteniators (II) increase the perception of the taste of (I) and mask its off flavors; typically these are thaumatine, neohesperidine dihydrochalcone (NHDC), glycyrrhyzine, and their mixtures. The mixtures are prepared by dissolving (I) and (II) and spray drying this to form a homogeneous powder. The particle size of the final product is preferably 10 - 100 mu m, with a Gaussian distribution. The weight ratio of (I) : (II) is preferably in the range 97:3 - 90:10
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97810941A EP0920861A1 (en) | 1997-12-03 | 1997-12-03 | Taste masking powders for pharmaceuticals |
| PCT/IB1998/001915 WO1999027915A1 (en) | 1997-12-03 | 1998-12-02 | Masking agent in powder form for pharmaceutical flavours |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1030881A1 true HK1030881A1 (en) | 2001-05-25 |
Family
ID=8230505
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK01101524A HK1030881A1 (en) | 1997-12-03 | 2001-03-02 | Masking agent in powder form for pharmaceutical flavours |
Country Status (8)
| Country | Link |
|---|---|
| EP (2) | EP0920861A1 (en) |
| CN (1) | CN1163221C (en) |
| AT (1) | ATE225163T1 (en) |
| AU (1) | AU1170799A (en) |
| DE (1) | DE69808509T2 (en) |
| ES (1) | ES2185228T3 (en) |
| HK (1) | HK1030881A1 (en) |
| WO (1) | WO1999027915A1 (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2380936B (en) * | 2001-10-18 | 2003-07-09 | Reckitt Benckiser Healthcare | Improvements in or relating to compositions |
| FR2859603B1 (en) * | 2003-09-11 | 2005-12-30 | Christian Fenioux | USE OF NEOHESPERIDINE DIHYDROCHALCONE IN ORAL COMPOSITIONS COMPRISING VITAMINS AND / OR MINERALS |
| EP1623630A1 (en) * | 2004-08-03 | 2006-02-08 | Pancosma S.A. | Powdered sweetener for human nutrition |
| US20100092638A1 (en) * | 2006-10-24 | 2010-04-15 | Chad Allen Hansen | Consumables |
| WO2008049258A1 (en) * | 2006-10-24 | 2008-05-02 | Givaudan Sa | Consumables |
| CN101558827B (en) * | 2009-02-18 | 2012-05-02 | 麦仑（厦门）生物科技有限公司 | Compound sweetening agent for producing feed by being combined with spray drying technology and preparation method thereof |
| CN104705618B (en) * | 2015-04-09 | 2017-03-15 | 佛山市金骏康健康科技有限公司 | A kind of manufacture method of new-type compound sweetener |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19617487A1 (en) * | 1996-05-02 | 1997-11-06 | Merck Patent Gmbh | Taste improvement of active pharmaceutical ingredients |
| DE19639343C2 (en) * | 1996-09-25 | 1998-10-08 | Suedzucker Ag | Comprimate containing a sweetener mixture |
-
1997
- 1997-12-03 EP EP97810941A patent/EP0920861A1/en not_active Withdrawn
-
1998
- 1998-12-02 WO PCT/IB1998/001915 patent/WO1999027915A1/en active IP Right Grant
- 1998-12-02 DE DE69808509T patent/DE69808509T2/en not_active Expired - Fee Related
- 1998-12-02 CN CNB988130343A patent/CN1163221C/en not_active Expired - Fee Related
- 1998-12-02 ES ES98954686T patent/ES2185228T3/en not_active Expired - Lifetime
- 1998-12-02 AU AU11707/99A patent/AU1170799A/en not_active Abandoned
- 1998-12-02 AT AT98954686T patent/ATE225163T1/en not_active IP Right Cessation
- 1998-12-02 EP EP98954686A patent/EP1032372B1/en not_active Expired - Lifetime
-
2001
- 2001-03-02 HK HK01101524A patent/HK1030881A1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1285740A (en) | 2001-02-28 |
| DE69808509T2 (en) | 2003-06-18 |
| WO1999027915A1 (en) | 1999-06-10 |
| ATE225163T1 (en) | 2002-10-15 |
| CN1163221C (en) | 2004-08-25 |
| EP1032372B1 (en) | 2002-10-02 |
| DE69808509D1 (en) | 2002-11-07 |
| AU1170799A (en) | 1999-06-16 |
| EP0920861A1 (en) | 1999-06-09 |
| EP1032372A1 (en) | 2000-09-06 |
| ES2185228T3 (en) | 2003-04-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PF | Patent in force | ||
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20071202 |