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Priority to GT200700006ApriorityCriticalpatent/GT200700006A/en
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Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
HETEROCICLOS DE 1,4-DIHIDROPIRIDINA-CONDENSADOS, PROCESOS PARA PREPARAR LOS MISMOS, USO Y COMPOSICIONES QUE LOS CONTIENEN. LA INVENCIÓN SE REFIERE A HETEROCICLOS DIHIDROPIRIDINA-CONDENSADOS SUSTITUIDOS ÚTILES PARA EL TRATAMIENTO DE ENFERMEDAD DE CÁNCER, ESPECIALMENTE PARA PREVENIR LA DIVISIÓN DE CÉLULAS CANCERÍGENAS. ESTOS COMPUESTOS ACTÚAN COMO INHIBIDORES DE AURORA A Y/O B QUINASAS. T20071,4-DIHYDROPIRIDINE-CONDENSED HETEROCICLES, PROCESSES TO PREPARE THE SAME, USE AND COMPOSITIONS CONTAINING THEM. THE INVENTION REFERS TO USED SUBSTITUTED DIHYDROPIRIDINE-CONDENSED HETEROCICLES FOR THE TREATMENT OF CANCER DISEASE, ESPECIALLY TO PREVENT THE DIVISION OF CANCERIGENE CELLS. THESE COMPOUNDS ACT AS AURORA A AND / OR B KINASAS INHIBITORS. T2007
GT200700006A2007-01-262007-01-26
1,4-DIHYDROPIRIDINE-CONDENSED HETEROCICLES, PROCESSES TO PREPARE THE SAME, USE AND COMPOSITIONS CONTAINING THEM
GT200700006A
(en)
Use of a compound derived from quinazoline to treat cancer; use of the compound and another antineoplastic compound; quinazoline derived compounds; and pharmaceutical composition comprising them.
Compounds derived from substituted quinazolines, inhibitors of potassium ion channels; pharmaceutical composition comprising them; use of the compound to treat or prevent arrhythmias, control heart rate, among others.
Compounds derived from substituted nicotinamide; pharmaceutical composition that includes them; use for the treatment and / or prevention of cancer, infections, inflammatory and autoimmune diseases.
Compounds derived from isoindolones; pharmaceutical composition comprising them; and its use as mek kinase inhibitors to treat hyperproliferative and / or inflammatory diseases such as cancer, rheumatoid arthritis among others.
Compounds derived from 5-alkynyl-pyrimidines, kinase inhibitors; pharmaceutical compositions containing them; and its use for the treatment and / or prevention of cancer, infections, inflammatory and autoimmune diseases.
Compounds derived from 2-oxo-piperidine and 1,1-dioxide-thiazine, mdm2 inhibitors; pharmaceutical composition that includes them; and its use for the treatment of cancer.