GT200300072AA - AMINO ACIDS WITH AFFINITY FOR ALFA2DELTA PROTEIN (FRACTIONARY APPLICATION - Google Patents
AMINO ACIDS WITH AFFINITY FOR ALFA2DELTA PROTEIN (FRACTIONARY APPLICATIONInfo
- Publication number
- GT200300072AA GT200300072AA GT200300072AK GT200300072K GT200300072AA GT 200300072A A GT200300072A A GT 200300072AA GT 200300072A K GT200300072A K GT 200300072AK GT 200300072 K GT200300072 K GT 200300072K GT 200300072A A GT200300072A A GT 200300072AA
- Authority
- GT
- Guatemala
- Prior art keywords
- alfa2delta
- fractionary
- affinity
- protein
- application
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
- A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
LA PRESENTE INVENCION SE REFIERE A COMPUESTOS DE LA FORMULA GENERAL EN DONDE R1,R2,R3, SON GRUPOS FUNCIONALES DESCRITOS EN EL EXPEDIENTE. ESTOS COMPUESTOS SE UNEN A LA SUBUNIDAD ALFA2DELTA POR LO QUE SON DE UTILIDAD ENTHE PRESENT INVENTION REFERS TO COMPOUNDS OF THE GENERAL FORMULA WHERE R1, R2, R3, ARE FUNCTIONAL GROUPS DESCRIBED IN THE RECORD. THESE COMPOUNDS JOIN THE ALFA2DELTA SUBUNITY FOR WHICH THEY ARE USEFUL IN
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36841302P | 2002-03-28 | 2002-03-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
GT200300072AA true GT200300072AA (en) | 2006-08-23 |
Family
ID=28675482
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GT200300072A GT200300072A (en) | 2002-03-28 | 2003-03-28 | AMINO ACIDS WITH AFFINITY FOR THE PROTEIN ALFA-2-DELTA. |
GT200300072AK GT200300072AA (en) | 2002-03-28 | 2003-03-28 | AMINO ACIDS WITH AFFINITY FOR ALFA2DELTA PROTEIN (FRACTIONARY APPLICATION |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GT200300072A GT200300072A (en) | 2002-03-28 | 2003-03-28 | AMINO ACIDS WITH AFFINITY FOR THE PROTEIN ALFA-2-DELTA. |
Country Status (43)
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
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DE10129693A1 (en) * | 2001-06-22 | 2003-01-02 | Jan Loock | Process for the extracorporeal qualitative and / or quantitative detection of neurotoxic substances in the blood plasma of an individual |
NI200300043A (en) * | 2002-03-28 | 2003-11-05 | Warner Lambert Co | AMINO ACIDS WITH AFFINITY FOR THE PROTEIN a2DELTA. |
US7419981B2 (en) | 2002-08-15 | 2008-09-02 | Pfizer Inc. | Synergistic combinations of an alpha-2-delta ligand and a cGMP phosphodieterse 5 inhibitor |
CA2451267A1 (en) | 2002-12-13 | 2004-06-13 | Warner-Lambert Company Llc | Pharmaceutical uses for alpha2delta ligands |
EP1680125A1 (en) * | 2003-07-02 | 2006-07-19 | Warner-Lambert Company LLC | Combination of an allosteric inhibitor of matrix metalloproteinase-13 and a ligand to an alpha-2-delta receptor |
RU2344121C2 (en) * | 2003-09-25 | 2009-01-20 | УОРНЕР-ЛАМБЕРТ КОМПАНИ Эл-Эл-Си | Method of treatment of diseases at mammals |
EP1667957A2 (en) * | 2003-09-25 | 2006-06-14 | Warner-Lambert Company LLC | Amino acids with affinity for the alpha2delta-protein |
KR100847922B1 (en) * | 2004-03-12 | 2008-07-22 | 워너-램버트 캄파니 엘엘씨 | C1-symmetric bisphosphine ligands and their use in the asymmetric synthesis of pregabalin |
AU2005264036A1 (en) * | 2004-07-09 | 2006-01-26 | Warner-Lambert Company Llc | Preparation of beta-amino acids having affinity for the alpha-2-delta protein |
WO2006092692A1 (en) * | 2005-03-01 | 2006-09-08 | Pfizer Limited | Use of combinations of pde7 inhibitors and alpha-2-delty ligands for the treatment of neuropathic pain |
AU2006226046A1 (en) * | 2005-03-24 | 2006-09-28 | Pharmacia & Upjohn Company Llc | Preparation of optically pure beta-amino acids having affinity for the alpha-2-delta protein |
WO2007052134A1 (en) * | 2005-11-04 | 2007-05-10 | Pfizer Limited | (2s)-2-aminomethyl-5-ethyl heptanoic acid its pharmaceutical use |
US20090286875A1 (en) * | 2005-11-17 | 2009-11-19 | Pfizer, Inc. | Isocystene derivatives for the treatment of pain |
KR20080100284A (en) * | 2006-03-06 | 2008-11-14 | 화이자 프로덕츠 인코포레이티드 | Alpha-2-delta ligands for non-restorative sleep |
AR061728A1 (en) * | 2006-06-30 | 2008-09-17 | Pfizer Prod Inc | COMPOSITION FOR TREATMENT USING SELECTIVE COMPOUNDS ALFA-2-DELTA-1 |
US20110124705A1 (en) * | 2009-11-24 | 2011-05-26 | Xenoport, Inc. | Prodrugs of alpha-2-delta ligands, pharmaceutical compositions and uses thereof |
WO2012158795A1 (en) | 2011-05-17 | 2012-11-22 | Principia Biopharma Inc. | Pyrazolopyrimidine derivatives as tyrosine kinase inhibitors |
EA025496B1 (en) | 2011-05-17 | 2016-12-30 | Принсипиа Биофарма Инк. | Tyrosine kinase inhibitors |
DK2710007T3 (en) | 2011-05-17 | 2020-01-27 | Principia Biopharma Inc | kinase inhibitors |
CN103164756A (en) * | 2011-12-12 | 2013-06-19 | 苏州艾隆科技有限公司 | Management method and management system for precious medicines |
PT2892900T (en) | 2012-09-10 | 2017-11-06 | Principia Biopharma Inc | Pyrazolopyrimidine compounds as kinase inhibitors |
US8957080B2 (en) | 2013-04-09 | 2015-02-17 | Principia Biopharma Inc. | Tyrosine kinase inhibitors |
WO2015127310A1 (en) | 2014-02-21 | 2015-08-27 | Principia Biopharma Inc. | Salts and solid form of a btk inhibitor |
AU2015364335B2 (en) | 2014-12-18 | 2020-11-26 | Principia Biopharma Inc. | Treatment of pemphigus |
TW201718572A (en) | 2015-06-24 | 2017-06-01 | 普林斯匹亞生物製藥公司 | Tyrosine kinase inhibitors |
KR102391693B1 (en) | 2016-06-29 | 2022-04-29 | 프린시피아 바이오파마, 인코퍼레이티드 | 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-D]pyrimidin-1-yl]piperidine-1-carbonyl] Modified release formulation of -4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-ennitrile |
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