GR920100523A - Compounds. - Google Patents
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- GR920100523A GR920100523A GR920100523A GR920100523A GR920100523A GR 920100523 A GR920100523 A GR 920100523A GR 920100523 A GR920100523 A GR 920100523A GR 920100523 A GR920100523 A GR 920100523A GR 920100523 A GR920100523 A GR 920100523A
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Περιγράφονται νέα παράγωγα κυκλοεξαν-υλιδενίου τα οποία αναστέλλουν την παραγωγήν του TUMOR NECROSIS FACTOR (Παράγοντος Νεκρώσεως Ογκου) και είναι χρήσιμα εις την θεραπευτικήν αγωγήν νοσηρών καταστάσεων μεσολαβουμένων ή επιτεινουμένων υπό παραγωγής TNF. Αι ενώσεις της παρούσης εφευρέσεως είναι επίσης χρήσιμοι εις την παρεμβολή ή αναστολήν ενζυματικής ή καταλυτικής δράσεως της φωσφοροδιεστεράσης IV και είναι συνεπώς χρήσιμοι εις την θεραπευτικήν αγωγήν νοσηρών καταστάσεων εχούσων ανάγκην παρεμβολής ή αναστολής αυτών.ωNew cyclohexanylidene derivatives are described which inhibit the production of TUMOR NECROSIS FACTOR and are useful in the treatment of disease states mediated or exacerbated by TNF production. The compounds of the present invention are also useful in interfering with or inhibiting the enzymatic or catalytic activity of phosphodiesterase IV and are therefore useful in the treatment of disease states in need of interference or inhibition thereof.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GR92100523 | 1992-11-26 |
Publications (1)
Publication Number | Publication Date |
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GR920100523A true GR920100523A (en) | 1994-07-29 |
Family
ID=10941244
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR920100523A GR920100523A (en) | 1992-11-26 | 1992-11-26 | Compounds. |
Country Status (1)
Country | Link |
---|---|
GR (1) | GR920100523A (en) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2723937A1 (en) * | 1976-06-03 | 1977-12-15 | Upjohn Co | 4-AMINO-4-ARYLCYCLOHEXANONE COMPOUNDS, METHODS FOR THEIR MANUFACTURING, INTERMEDIATES USED IN THEIR MANUFACTURING, AND MEDICINAL PRODUCTS |
US4795757A (en) * | 1984-09-04 | 1989-01-03 | Rorer Pharmaceutical Corporation | Bisarylamines |
WO1991015451A1 (en) * | 1990-04-05 | 1991-10-17 | Smithkline Beecham Pharma Gmbh | Novel derivatives of phenyl-cycloalkanes and -cycloalkenes |
-
1992
- 1992-11-26 GR GR920100523A patent/GR920100523A/en unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2723937A1 (en) * | 1976-06-03 | 1977-12-15 | Upjohn Co | 4-AMINO-4-ARYLCYCLOHEXANONE COMPOUNDS, METHODS FOR THEIR MANUFACTURING, INTERMEDIATES USED IN THEIR MANUFACTURING, AND MEDICINAL PRODUCTS |
US4795757A (en) * | 1984-09-04 | 1989-01-03 | Rorer Pharmaceutical Corporation | Bisarylamines |
WO1991015451A1 (en) * | 1990-04-05 | 1991-10-17 | Smithkline Beecham Pharma Gmbh | Novel derivatives of phenyl-cycloalkanes and -cycloalkenes |
Non-Patent Citations (1)
Title |
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CHEMICAL ABSTRACTS, vol. 73, no. 21, 23 November 1970, Columbus, Ohio, US; abstract no. 109530f, '4-CYANO-4-PHENYLAMINOCYCLOHEXANES, BLOOD PRESSURE DEPRESSANTS' page 347 ; * |
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