GR890100379A - Pharmaceutical composition having good stability - Google Patents

Pharmaceutical composition having good stability

Info

Publication number
GR890100379A
GR890100379A GR890100379A GR890100379A GR890100379A GR 890100379 A GR890100379 A GR 890100379A GR 890100379 A GR890100379 A GR 890100379A GR 890100379 A GR890100379 A GR 890100379A GR 890100379 A GR890100379 A GR 890100379A
Authority
GR
Greece
Prior art keywords
pharmaceutical composition
good stability
binder
caramelose
disintegrators
Prior art date
Application number
GR890100379A
Other languages
Greek (el)
Other versions
GR1002098B (en
Inventor
Pierina Chiesa
Bherulal Nemichand Jain
Mohan Yatindra Joshi
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of GR890100379A publication Critical patent/GR890100379A/en
Publication of GR1002098B publication Critical patent/GR1002098B/en

Links

Abstract

A pharmaceutical composition is provided which has an exceptional stability, when dispersed in water, and with a pH from at least 9, and comprises a medicine sensitive to a low pH environment like pravastatin, one or more excipient(s) like lactose and/ or micro crystalline cellulose, one or more binders like microcrystalline cellulose (dry binder) or poly-vinyl-pyrrolidone (liquid binder), one or more disintegrators like sodium cross caramelose, one or more lubricants like magnesium stearate and one or more basic regulators like magnesium oxide.
GR890100379A 1989-06-08 1989-06-08 Pharmaceutical composition having good stability GR1002098B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR89100379 1989-06-08

Publications (2)

Publication Number Publication Date
GR890100379A true GR890100379A (en) 1991-11-15
GR1002098B GR1002098B (en) 1995-12-28

Family

ID=10939433

Family Applications (1)

Application Number Title Priority Date Filing Date
GR890100379A GR1002098B (en) 1989-06-08 1989-06-08 Pharmaceutical composition having good stability

Country Status (1)

Country Link
GR (1) GR1002098B (en)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0237200A2 (en) * 1986-02-13 1987-09-16 Takeda Chemical Industries, Ltd. Use of basic inorganic salts of magnesium or calcium for the stabilisation of benzimidazole derivatives
EP0244380A2 (en) * 1986-04-30 1987-11-04 Aktiebolaget Hässle Pharmaceutical formulations of acid labile substances for oral use
JPS62263124A (en) * 1986-05-07 1987-11-16 Sankyo Co Ltd Drug preparation for oral administration
EP0276807A2 (en) * 1987-01-27 1988-08-03 Warner-Lambert Company Lipid regulating compositions
EP0300111A1 (en) * 1987-07-22 1989-01-25 Farvalsa AG A moisture stable solid valproic acid formulation and a method of preparing the same
EP0336298A1 (en) * 1988-03-31 1989-10-11 E.R. Squibb & Sons, Inc. Pharmaceutical compositions having good stability

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0237200A2 (en) * 1986-02-13 1987-09-16 Takeda Chemical Industries, Ltd. Use of basic inorganic salts of magnesium or calcium for the stabilisation of benzimidazole derivatives
EP0244380A2 (en) * 1986-04-30 1987-11-04 Aktiebolaget Hässle Pharmaceutical formulations of acid labile substances for oral use
JPS62263124A (en) * 1986-05-07 1987-11-16 Sankyo Co Ltd Drug preparation for oral administration
EP0276807A2 (en) * 1987-01-27 1988-08-03 Warner-Lambert Company Lipid regulating compositions
EP0300111A1 (en) * 1987-07-22 1989-01-25 Farvalsa AG A moisture stable solid valproic acid formulation and a method of preparing the same
EP0336298A1 (en) * 1988-03-31 1989-10-11 E.R. Squibb & Sons, Inc. Pharmaceutical compositions having good stability

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 10, no. 10, 5th September 1988, page 414, abstract no. 79720k, Columbus, Ohio, US; & JP-A-62 263 124 (SANKYO CO., LTD) 16-11-1987 *
CLAIMS SEARCHED: ALL *

Also Published As

Publication number Publication date
GR1002098B (en) 1995-12-28

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