GR890100349A - Nucleoside and polynucleotide thiophosphoramidite and phosphorodithidate compounds and processes - Google Patents
Nucleoside and polynucleotide thiophosphoramidite and phosphorodithidate compounds and processesInfo
- Publication number
- GR890100349A GR890100349A GR890100349A GR890100349A GR890100349A GR 890100349 A GR890100349 A GR 890100349A GR 890100349 A GR890100349 A GR 890100349A GR 890100349 A GR890100349 A GR 890100349A GR 890100349 A GR890100349 A GR 890100349A
- Authority
- GR
- Greece
- Prior art keywords
- compounds
- processes
- phosphorodithidate
- thiophosphoramidite
- nucleoside
- Prior art date
Links
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- Saccharide Compounds (AREA)
Abstract
The invention hereby is related with a preparation method of new and useful nucleotid- thiophosphamides, poly nucleotid- phosphamide disulphates and poly nucleotid- thiophosphamid- phosphamid compounds as well as with processes where these compounds may be used to synthesise new mono nucleotides and poly nucleotides that have bonds of phosphodisulfate, phosphothiamate ester, phosphosulfate tri-esters and dianucleotid- phosphosulfate ester.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GR89100349 | 1989-05-26 |
Publications (1)
Publication Number | Publication Date |
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GR890100349A true GR890100349A (en) | 1994-03-31 |
Family
ID=10939423
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR890100349A GR890100349A (en) | 1989-05-26 | 1989-05-26 | Nucleoside and polynucleotide thiophosphoramidite and phosphorodithidate compounds and processes |
Country Status (1)
Country | Link |
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GR (1) | GR890100349A (en) |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4373071A (en) * | 1981-04-30 | 1983-02-08 | City Of Hope Research Institute | Solid-phase synthesis of polynucleotides |
US4415732A (en) * | 1981-03-27 | 1983-11-15 | University Patents, Inc. | Phosphoramidite compounds and processes |
JPS6251695A (en) * | 1985-08-29 | 1987-03-06 | Yuki Gosei Yakuhin Kogyo Kk | Synthesis of phosphoroamidite |
US4668777A (en) * | 1981-03-27 | 1987-05-26 | University Patents, Inc. | Phosphoramidite nucleoside compounds |
US4728730A (en) * | 1984-09-12 | 1988-03-01 | Wisconsin Alumini Research Foundation | Synthesis of nucleoside thiophosphoanhydrides |
-
1989
- 1989-05-26 GR GR890100349A patent/GR890100349A/en unknown
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4415732A (en) * | 1981-03-27 | 1983-11-15 | University Patents, Inc. | Phosphoramidite compounds and processes |
US4668777A (en) * | 1981-03-27 | 1987-05-26 | University Patents, Inc. | Phosphoramidite nucleoside compounds |
US4373071A (en) * | 1981-04-30 | 1983-02-08 | City Of Hope Research Institute | Solid-phase synthesis of polynucleotides |
US4728730A (en) * | 1984-09-12 | 1988-03-01 | Wisconsin Alumini Research Foundation | Synthesis of nucleoside thiophosphoanhydrides |
JPS6251695A (en) * | 1985-08-29 | 1987-03-06 | Yuki Gosei Yakuhin Kogyo Kk | Synthesis of phosphoroamidite |
Non-Patent Citations (12)
Title |
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CLAIMS SEARCHED: ALL * |
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 106, 1984, pages 6077-6079, The American Chemical Society, US; W.J. STEC et al.: "Automated solid-phase synthesis, separation, and stereochemistry of phosphorothioate analogues of oligodeoxyribonucleotides" * |
JOURNAL OF THE CHEMICAL SOCIETY. PERKIN TRANSACTIONS I., no. 8, August 1987, pages 1645-1656; J. BARANIAK et al.: "Ribonucleoside cyclic 3',5'-phosphoramidates: Synthesis, stereochemistry, and conversion into ribonucleoside cyclic 3',5'-phosphorothioates and -[18OÜphosphates" * |
PATENT ABSTRACTS OF JAPAN, vol. 11, no. 246 (C-439)[2693], 11th August 1987; & JP-A-62 51 695 (YUKI GOSEI YAKUHIN KOGYO K.K.) 06-03-1987 * |
SYNTHESIS, no. 5, May 1980, pages 397-400, Georg Thieme Verlag, Stuttgart, DE; Z.J. LESNIKOWSKI et al.: "Thymidine 3'-(2-chlorophenyl)-phosphoranilidate as a key intermediate in the synthesis of tetrahymidylic acid bearing phosphoryl of phosphorothioyl end groups" * |
TETRAHEDRON LETTERS, vol. 21, no. 43, 1980, pages 4153-4154, Pergamon Press, Oxford, GB; M.J. NEMER et al.: "Phosphoramidate analogues of diribonucleoside monophosphates" * |
TETRAHEDRON LETTERS, vol. 27, no. 46, 1986, pages 5575-5578, Pergamon Journals Ltd, GB; B.C. FROEHLER: "Deoxynucleoside H-phosphonate diester intermediates in the synthesis of internucleotide phosphate analogues" * |
TETRAHEDRON LETTERS, vol. 29, no. 24, 1988, pages 2911-2914, Pergamon Press, Oxford, GB; J. NIELSEN et al.: "Synthesis and characterization of dinucleoside phosphorodithioates" * |
TETRAHEDRON LETTERS, vol. 29, no. 43, 1988, pages 5517-5520, Pergamon Press, Oxford, GB; W.K.-D. BRILL et al.: "Synthesis of dinucleoside phosphorodithioates via thioamidites" * |
TETRAHEDRON LETTERS, vol. 29, no. 52, 1988, pages 6843-6846, Pergamon Press, Oxford, GB; N. FARSCHTSCHI et al.: "Preparation of a deoxynucleoside thiophosphoramidite intermediate in the synthesis of nucleoside phosphorodithioates" * |
TETRAHEDRON LETTERS, vol. 3, no. 5, 1989, pages 543-546, Pergamon Press, Oxford, GB; A. GRANDAS et al.: "Synthesis of deoxycytidine oligomers containing phosphorodithioate linkages" * |
TETRAHEDRON LETTERS, vol. 30, no. 16, 1989, pages 2157-2160, Pergamon Press, Oxford, GB; J. STAWINSKI et al.: "Nucleoside H-phosphonates. X. Studies on nucleoside hydrogenphosphonothioate diester synthesis" * |
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