GR880100839A - Tromethamine salt of 1-methyl-b-oxo-a-(phenylcarbamoyl)-2-pyrrolepropionitrile - Google Patents

Tromethamine salt of 1-methyl-b-oxo-a-(phenylcarbamoyl)-2-pyrrolepropionitrile

Info

Publication number
GR880100839A
GR880100839A GR880100839A GR880100839A GR880100839A GR 880100839 A GR880100839 A GR 880100839A GR 880100839 A GR880100839 A GR 880100839A GR 880100839 A GR880100839 A GR 880100839A GR 880100839 A GR880100839 A GR 880100839A
Authority
GR
Greece
Prior art keywords
pyrrolepropionitrile
phenylcarbamoyl
oxo
methyl
salt
Prior art date
Application number
GR880100839A
Other languages
Greek (el)
Inventor
Gordon Dr Walker
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of GR880100839A publication Critical patent/GR880100839A/en

Links

Abstract

This invention refers to a new, pharmaceutically accepted, meta tromethamine salt of 1-methyl-beta-oxo-alpha-(phenylcarbamoyl)-2-pyrrolepropionitrile for pharmaceutical compositions including the referred to salt and a therapeutic method of treating inflammatory and arthritic conditions in mammals by administering the referred to salt to mammals in need of such treatment.
GR880100839A 1988-12-15 1988-12-15 Tromethamine salt of 1-methyl-b-oxo-a-(phenylcarbamoyl)-2-pyrrolepropionitrile GR880100839A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR88100839 1988-12-15

Publications (1)

Publication Number Publication Date
GR880100839A true GR880100839A (en) 1994-03-31

Family

ID=10938934

Family Applications (1)

Application Number Title Priority Date Filing Date
GR880100839A GR880100839A (en) 1988-12-15 1988-12-15 Tromethamine salt of 1-methyl-b-oxo-a-(phenylcarbamoyl)-2-pyrrolepropionitrile

Country Status (1)

Country Link
GR (1) GR880100839A (en)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2633891A1 (en) * 1975-07-28 1977-02-17 Roussel Uclaf NEW SALT OF ALPHA-METHYLBENZOYL-5-THIOPHEN-2-ACETIC ACID, PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS
EP0021207A1 (en) * 1979-06-11 1981-01-07 Ciba-Geigy Ag Alphacarbamoyl-pyrrolpropionitriles, process for their preparation and pharmaceutical preparations containing them
DE3036367A1 (en) * 1979-09-27 1981-04-16 Kahan Ilona WATER-SOLUBLE DERIVATIVES OF NONSTEROIDAL ANTI-FLAMMABLE AGENTS, AND METHOD FOR PRODUCING SUCH DERIVATIVES, AND THERAPEUTIC PREPARATIONS CONTAINING SUCH DERIVATIVES
US4644010A (en) * 1982-09-28 1987-02-17 Ciba-Geigy Corporation Certain β-oxo-α-carbamoylpyrrolepropionitriles
EP0230125A1 (en) * 1985-12-23 1987-07-29 Merck & Co. Inc. Admixtures of diflunisal and tromethamine
US4698361A (en) * 1986-05-28 1987-10-06 Schiena Michele G Di Tris-chydroxymethyl) aminomethane salt of 4-chloro-N-furfuryl-5-sulfamoyl anthranilic acid and diuretic compositions containing the same
EP0259990A1 (en) * 1986-08-25 1988-03-16 Merck & Co. Inc. Rapid acting combination of sodium sulindac and a base

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2633891A1 (en) * 1975-07-28 1977-02-17 Roussel Uclaf NEW SALT OF ALPHA-METHYLBENZOYL-5-THIOPHEN-2-ACETIC ACID, PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS
EP0021207A1 (en) * 1979-06-11 1981-01-07 Ciba-Geigy Ag Alphacarbamoyl-pyrrolpropionitriles, process for their preparation and pharmaceutical preparations containing them
DE3036367A1 (en) * 1979-09-27 1981-04-16 Kahan Ilona WATER-SOLUBLE DERIVATIVES OF NONSTEROIDAL ANTI-FLAMMABLE AGENTS, AND METHOD FOR PRODUCING SUCH DERIVATIVES, AND THERAPEUTIC PREPARATIONS CONTAINING SUCH DERIVATIVES
US4644010A (en) * 1982-09-28 1987-02-17 Ciba-Geigy Corporation Certain β-oxo-α-carbamoylpyrrolepropionitriles
EP0230125A1 (en) * 1985-12-23 1987-07-29 Merck & Co. Inc. Admixtures of diflunisal and tromethamine
US4698361A (en) * 1986-05-28 1987-10-06 Schiena Michele G Di Tris-chydroxymethyl) aminomethane salt of 4-chloro-N-furfuryl-5-sulfamoyl anthranilic acid and diuretic compositions containing the same
EP0259990A1 (en) * 1986-08-25 1988-03-16 Merck & Co. Inc. Rapid acting combination of sodium sulindac and a base

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CLAIMS SEARCHED: ALL *
PHARMACOLOGICAL REVIEWS, vol. 14, no. 3, September 1962, pages 447-472, The Williams & Wilkins Co., Baltimore, MD, US; G.G. NAHAS: "The pharmacology of tris(hydroxymethyl) aminomethane (tham)" *

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