GR3030314T3 - Process for selectively isolating bêta-2'-deoxy-2',2'-difluorocytidine or its salts. - Google Patents

Process for selectively isolating bêta-2'-deoxy-2',2'-difluorocytidine or its salts.

Info

Publication number
GR3030314T3
GR3030314T3 GR990401401T GR990401401T GR3030314T3 GR 3030314 T3 GR3030314 T3 GR 3030314T3 GR 990401401 T GR990401401 T GR 990401401T GR 990401401 T GR990401401 T GR 990401401T GR 3030314 T3 GR3030314 T3 GR 3030314T3
Authority
GR
Greece
Prior art keywords
bêta
difluorocytidine
deoxy
salts
selectively isolating
Prior art date
Application number
GR990401401T
Other languages
Greek (el)
Inventor
Ta-Sen Chou
Perry Clark Heath
Lawrence Edward Patterson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP88307750A external-priority patent/EP0306190B1/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of GR3030314T3 publication Critical patent/GR3030314T3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
GR990401401T 1987-08-28 1999-05-27 Process for selectively isolating bêta-2'-deoxy-2',2'-difluorocytidine or its salts. GR3030314T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9072587A 1987-08-28 1987-08-28
EP88307750A EP0306190B1 (en) 1987-08-28 1988-08-22 Process for preparing intermediates useful in the preparation of 2',2'-difluoronucleosides

Publications (1)

Publication Number Publication Date
GR3030314T3 true GR3030314T3 (en) 1999-09-30

Family

ID=26116719

Family Applications (2)

Application Number Title Priority Date Filing Date
GR990401401T GR3030314T3 (en) 1987-08-28 1999-05-27 Process for selectively isolating bêta-2'-deoxy-2',2'-difluorocytidine or its salts.
GR20010401360T GR3036500T3 (en) 1987-08-28 2001-08-31 Method for preparing 2',deoxy-2',2'-difluornucleosides

Family Applications After (1)

Application Number Title Priority Date Filing Date
GR20010401360T GR3036500T3 (en) 1987-08-28 2001-08-31 Method for preparing 2',deoxy-2',2'-difluornucleosides

Country Status (1)

Country Link
GR (2) GR3030314T3 (en)

Also Published As

Publication number Publication date
GR3036500T3 (en) 2001-11-30

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