GR3026444T3 - Anthracycline prodrugs - Google Patents

Anthracycline prodrugs

Info

Publication number
GR3026444T3
GR3026444T3 GR980400636T GR980400636T GR3026444T3 GR 3026444 T3 GR3026444 T3 GR 3026444T3 GR 980400636 T GR980400636 T GR 980400636T GR 980400636 T GR980400636 T GR 980400636T GR 3026444 T3 GR3026444 T3 GR 3026444T3
Authority
GR
Greece
Prior art keywords
anthracycline prodrugs
anthracycline
prodrugs
Prior art date
Application number
GR980400636T
Other languages
Greek (el)
Inventor
Peter D Senter
Mark G Saulnier
Joseph P Brown
David E Kerr
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/211,301 external-priority patent/US4975278A/en
Priority claimed from EP88112646A external-priority patent/EP0302473B1/en
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of GR3026444T3 publication Critical patent/GR3026444T3/en

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6891Pre-targeting systems involving an antibody for targeting specific cells
    • A61K47/6899Antibody-Directed Enzyme Prodrug Therapy [ADEPT]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/252Naphthacene radicals, e.g. daunomycins, adriamycins
GR980400636T 1987-08-04 1998-03-24 Anthracycline prodrugs GR3026444T3 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US8138287A 1987-08-04 1987-08-04
US16106888A 1988-02-26 1988-02-26
US07/211,301 US4975278A (en) 1988-02-26 1988-06-29 Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells
EP88112646A EP0302473B1 (en) 1987-08-04 1988-08-03 Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells

Publications (1)

Publication Number Publication Date
GR3026444T3 true GR3026444T3 (en) 1998-06-30

Family

ID=27441445

Family Applications (1)

Application Number Title Priority Date Filing Date
GR980400636T GR3026444T3 (en) 1987-08-04 1998-03-24 Anthracycline prodrugs

Country Status (2)

Country Link
ES (1) ES2113904T3 (en)
GR (1) GR3026444T3 (en)

Also Published As

Publication number Publication date
ES2113904T3 (en) 1998-05-16

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