GR3019961T3 - Inhibition of aggregation of drug containing particles - Google Patents

Inhibition of aggregation of drug containing particles

Info

Publication number
GR3019961T3
GR3019961T3 GR960401334T GR960401334T GR3019961T3 GR 3019961 T3 GR3019961 T3 GR 3019961T3 GR 960401334 T GR960401334 T GR 960401334T GR 960401334 T GR960401334 T GR 960401334T GR 3019961 T3 GR3019961 T3 GR 3019961T3
Authority
GR
Greece
Prior art keywords
aggregation
inhibition
containing particles
drug containing
liposomes
Prior art date
Application number
GR960401334T
Other languages
Greek (el)
Inventor
Crispin G S Eley
Eric A Forssen
Original Assignee
Vestar Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vestar Inc filed Critical Vestar Inc
Publication of GR3019961T3 publication Critical patent/GR3019961T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient

Abstract

A method and composition for the prevention of aggregation of liposomes which include a multivalent anion disposed on the outer surface thereof comprises the addition of a divalent cation to the external aqueous phase.
GR960401334T 1992-02-11 1996-05-17 Inhibition of aggregation of drug containing particles GR3019961T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA002108026A CA2108026C (en) 1992-02-11 1992-02-11 Inhibition of aggregation of drug containing particles
PCT/US1992/001083 WO1993015720A1 (en) 1992-02-11 1992-02-11 Inhibition of aggregation of drug containing particles

Publications (1)

Publication Number Publication Date
GR3019961T3 true GR3019961T3 (en) 1996-08-31

Family

ID=4152422

Family Applications (1)

Application Number Title Priority Date Filing Date
GR960401334T GR3019961T3 (en) 1992-02-11 1996-05-17 Inhibition of aggregation of drug containing particles

Country Status (10)

Country Link
EP (1) EP0579703B1 (en)
JP (1) JPH06506460A (en)
AT (1) ATE136457T1 (en)
AU (1) AU652247B2 (en)
CA (1) CA2108026C (en)
DE (1) DE69209830T2 (en)
DK (1) DK0579703T3 (en)
ES (1) ES2088135T3 (en)
GR (1) GR3019961T3 (en)
WO (1) WO1993015720A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4420727A1 (en) * 1994-06-15 1995-12-21 Rovi Gmbh Skin-friendly aqueous liposome dispersions containing alpha-hydroxycarboxylic acids and / or alpha-hydroxyketo acids in their salt form
US6120751A (en) 1997-03-21 2000-09-19 Imarx Pharmaceutical Corp. Charged lipids and uses for the same
US20040146551A1 (en) 2002-11-01 2004-07-29 Biodelivery Sciences International, Inc. Geodate delivery vehicles
CN1859906A (en) * 2003-10-15 2006-11-08 株式会社纳米卵 Composition containing retinoic acid nanoparticles coated with polyvalent metal inorganic salt
JP4422681B2 (en) * 2003-10-15 2010-02-24 株式会社ナノエッグ Method for producing polyvalent metal inorganic salt-coated retinoic acid nanoparticles and nanoparticles obtained by the production method

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE63518B1 (en) * 1987-11-18 1995-05-03 Vestar Inc Multiple step entrapment/loading procedure for preparing lipophilic drug-containing liposomes

Also Published As

Publication number Publication date
AU652247B2 (en) 1994-08-18
DE69209830T2 (en) 1996-11-28
EP0579703B1 (en) 1996-04-10
EP0579703A1 (en) 1994-01-26
ATE136457T1 (en) 1996-04-15
DK0579703T3 (en) 1996-08-05
CA2108026A1 (en) 1993-08-12
CA2108026C (en) 2003-08-19
WO1993015720A1 (en) 1993-08-19
ES2088135T3 (en) 1996-08-01
DE69209830D1 (en) 1996-05-15
AU1645692A (en) 1993-09-03
JPH06506460A (en) 1994-07-21

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