GR1005716B - New, gradually aminomethylated polystyrene resins for solid phase peptid and organic synthesis. - Google Patents

New, gradually aminomethylated polystyrene resins for solid phase peptid and organic synthesis.

Info

Publication number
GR1005716B
GR1005716B GR20060100401A GR20060100401A GR1005716B GR 1005716 B GR1005716 B GR 1005716B GR 20060100401 A GR20060100401 A GR 20060100401A GR 20060100401 A GR20060100401 A GR 20060100401A GR 1005716 B GR1005716 B GR 1005716B
Authority
GR
Greece
Prior art keywords
solid phase
gradually
aminomethylated
new
organic synthesis
Prior art date
Application number
GR20060100401A
Other languages
Greek (el)
Inventor
Χρηστος Ζηκος
Νικολαος Φερδεριγος
Original Assignee
Βιομεντικα Λαϊφ Σαϊενσις Α.Ε.
Χρηστος Ζηκος
Νικολαος Φερδεριγος
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Βιομεντικα Λαϊφ Σαϊενσις Α.Ε., Χρηστος Ζηκος, Νικολαος Φερδεριγος filed Critical Βιομεντικα Λαϊφ Σαϊενσις Α.Ε.
Priority to GR20060100401A priority Critical patent/GR1005716B/en
Publication of GR1005716B publication Critical patent/GR1005716B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
    • C08F8/32—Introducing nitrogen atoms or nitrogen-containing groups by reaction with amines

Landscapes

  • Chemical & Material Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

Abstract

The present invention refers to the development of novel, aminomethylated copolymers of polystyrene with divinylbenzene which are gradually aminomethylated groups from the center of the polymer beads to their surface, with less aminomethylated groups in the center of the polymer beads and more in their surface. The new resins, are characterized of low cost, controlled substitution, and can be made with relative ease in a short period of time. The new resins are suitable supports for solid phasepeptide synthesis and in general for solid phase peptide synthesis and in general for solid phase organic synthesis.
GR20060100401A 2006-07-13 2006-07-13 New, gradually aminomethylated polystyrene resins for solid phase peptid and organic synthesis. GR1005716B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GR20060100401A GR1005716B (en) 2006-07-13 2006-07-13 New, gradually aminomethylated polystyrene resins for solid phase peptid and organic synthesis.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR20060100401A GR1005716B (en) 2006-07-13 2006-07-13 New, gradually aminomethylated polystyrene resins for solid phase peptid and organic synthesis.

Publications (1)

Publication Number Publication Date
GR1005716B true GR1005716B (en) 2007-11-07

Family

ID=37943992

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20060100401A GR1005716B (en) 2006-07-13 2006-07-13 New, gradually aminomethylated polystyrene resins for solid phase peptid and organic synthesis.

Country Status (1)

Country Link
GR (1) GR1005716B (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3763271A (en) * 1969-07-01 1973-10-02 Gen Electric Method for introducing imido alkylene substitution into aromatic carbo cyclic organic polymers
US5464875A (en) * 1993-08-20 1995-11-07 Bayer Aktiengesellschaft Process for preparing weakly-basic anion exchangers and reagents suitable for this purpose
WO1996025440A1 (en) * 1995-02-16 1996-08-22 British Technology Group Limited Polymeric compounds

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3763271A (en) * 1969-07-01 1973-10-02 Gen Electric Method for introducing imido alkylene substitution into aromatic carbo cyclic organic polymers
US5464875A (en) * 1993-08-20 1995-11-07 Bayer Aktiengesellschaft Process for preparing weakly-basic anion exchangers and reagents suitable for this purpose
WO1996025440A1 (en) * 1995-02-16 1996-08-22 British Technology Group Limited Polymeric compounds

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ADAMS J H ET AL.: "A Reinvestigation of the Preparation, Properties, and Applications of Aminomethyl and 4-Methylbenzhydramine Polystyrene Resins", JOURNAL OF ORGANIC CHEMISTRY, vol. 63, 1998, pages 3706 - 3716, XP002430922 *
ZIKOS C C ET AL: "Preparation of High Capacity Aminomethyl-Polystyrene Resin", 22 May 1995, TETRAHEDRON LETTERS, ELSEVIER, AMSTERDAM, NL, PAGE(S) 3741-3744, ISSN: 0040-4039, XP004028067 *

Similar Documents

Publication Publication Date Title
MY173629A (en) Dosage form
HK1185357A1 (en) Modified antigen binding molecules with altered cell signaling activity
GB2477701B (en) Capacitive deionization cell with radial flow
TW200728389A (en) Stable polyamides for simultaneous solid phase polymerization of polyesters and polyamides
GB0821611D0 (en) Indenofluorene polymer based organic semiconductor materials
EP1913126A4 (en) Co-culture bioreactor system
EP2567964A3 (en) Monomer Compositions for the Synthesis of RNA, Methods of Synthesis, and Methods of Deprotection
MY158219A (en) Method for activation of helper t cell and composition for use in the method
PL2125639T3 (en) Anaerobic digester employing circular tank
WO2006050433A3 (en) Methods for detection of microrna molecules
EP2021382A4 (en) Supported antistatic polymerization catalyst
WO2010104865A3 (en) Single protein nanocapsules for protein delivery with long-term effect
WO2008042289A3 (en) Polymer synthetic technique
ZA201002078B (en) Bubble column type hydrocarbon synthesis reactor,and hydrocarbon synthesis reaction system having the same
WO2008054725A3 (en) Spheronized polymer particles
EP2116608A3 (en) Polyester synthesis
EP1964918A4 (en) Protein which can serve as nucleus for polymerization of protein polymer, cell having the polymer introduced therein, and process for production of the cell
EP2163581A4 (en) Polyester resin composition for injection molding, light reflector base, and light reflector
WO2010057014A3 (en) Capturing and delivering molecules in a mammal
GR1005716B (en) New, gradually aminomethylated polystyrene resins for solid phase peptid and organic synthesis.
PL1694755T3 (en) Expandable polystyrene granulates with a bi- or multi-modal molecular-weight distribution
ATE444117T1 (en) POLYMERIZATION PROCESS WITH OPTIMIZED REACTOR DESIGN
WO2011115812A8 (en) Affinity peptides toward bmp-2
WO2009120379A3 (en) Small diameter calcium-aluminate based catalyst supports by extrusion and pelletizing
WO2008069940A3 (en) Multi-microrna methods and compositions

Legal Events

Date Code Title Description
PG Patent granted
ML Lapse due to non-payment of fees

Effective date: 20110202