GR1004330B - Pharmaceutical dosage form for the delivery of organic nitrates - Google Patents
Pharmaceutical dosage form for the delivery of organic nitratesInfo
- Publication number
- GR1004330B GR1004330B GR20020100442A GR2002100442A GR1004330B GR 1004330 B GR1004330 B GR 1004330B GR 20020100442 A GR20020100442 A GR 20020100442A GR 2002100442 A GR2002100442 A GR 2002100442A GR 1004330 B GR1004330 B GR 1004330B
- Authority
- GR
- Greece
- Prior art keywords
- dosage form
- organic nitrates
- tablet
- membrane
- delivery
- Prior art date
Links
Abstract
In the present invention, a pharmaceutical dosage form for the delivery of organic nitrate in patients is described. The dosage form is based on the use of a semipermeable membrane (2) which covers a tablet (1) which contains a combination of one or more organic nitrates with excipients. The membrane (2) determines the water input rate towards the inner tablet (1). The osmotic pressure that develops, drives the contents of the tablet to exit through a hole (5) on the membrane, with a specific and controlled rate, regardless of the conditions of the gastrointestinal tract. It is possible that an amount of the organic nitrates is also released immediately upon administration of the dosage form, from a layer (3) placed outside the semipermeable membrane (2). Thus, the organism is provided with organic nitrates as desired in order to achieve optimum therapeutic results. Lastly, it is possible to have an external protective layer (4) which provides protection, improves stability and a long life to the dosage form, and also facilitates administration to the patient.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GR20020100442A GR1004330B (en) | 2002-10-14 | 2002-10-14 | Pharmaceutical dosage form for the delivery of organic nitrates |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GR20020100442A GR1004330B (en) | 2002-10-14 | 2002-10-14 | Pharmaceutical dosage form for the delivery of organic nitrates |
Publications (1)
Publication Number | Publication Date |
---|---|
GR1004330B true GR1004330B (en) | 2003-09-05 |
Family
ID=29559941
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR20020100442A GR1004330B (en) | 2002-10-14 | 2002-10-14 | Pharmaceutical dosage form for the delivery of organic nitrates |
Country Status (1)
Country | Link |
---|---|
GR (1) | GR1004330B (en) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1983002056A1 (en) * | 1981-12-18 | 1983-06-23 | Key Pharma | Expandable lattice of polyvinyl alcohol and polyethylene glycol |
WO1999062496A1 (en) * | 1998-06-03 | 1999-12-09 | Alza Corporation | Methods and devices for providing prolonged drug therapy |
-
2002
- 2002-10-14 GR GR20020100442A patent/GR1004330B/en unknown
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1983002056A1 (en) * | 1981-12-18 | 1983-06-23 | Key Pharma | Expandable lattice of polyvinyl alcohol and polyethylene glycol |
WO1999062496A1 (en) * | 1998-06-03 | 1999-12-09 | Alza Corporation | Methods and devices for providing prolonged drug therapy |
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