GR1004330B - Pharmaceutical dosage form for the delivery of organic nitrates - Google Patents

Pharmaceutical dosage form for the delivery of organic nitrates

Info

Publication number
GR1004330B
GR1004330B GR20020100442A GR2002100442A GR1004330B GR 1004330 B GR1004330 B GR 1004330B GR 20020100442 A GR20020100442 A GR 20020100442A GR 2002100442 A GR2002100442 A GR 2002100442A GR 1004330 B GR1004330 B GR 1004330B
Authority
GR
Greece
Prior art keywords
dosage form
organic nitrates
tablet
membrane
delivery
Prior art date
Application number
GR20020100442A
Other languages
Greek (el)
Inventor
Σπυριδων Φωτεινος
Αικατερινη Τσαρδακα
Original Assignee
Lavipharm A.E.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lavipharm A.E. filed Critical Lavipharm A.E.
Priority to GR20020100442A priority Critical patent/GR1004330B/en
Publication of GR1004330B publication Critical patent/GR1004330B/en

Links

Abstract

In the present invention, a pharmaceutical dosage form for the delivery of organic nitrate in patients is described. The dosage form is based on the use of a semipermeable membrane (2) which covers a tablet (1) which contains a combination of one or more organic nitrates with excipients. The membrane (2) determines the water input rate towards the inner tablet (1). The osmotic pressure that develops, drives the contents of the tablet to exit through a hole (5) on the membrane, with a specific and controlled rate, regardless of the conditions of the gastrointestinal tract. It is possible that an amount of the organic nitrates is also released immediately upon administration of the dosage form, from a layer (3) placed outside the semipermeable membrane (2). Thus, the organism is provided with organic nitrates as desired in order to achieve optimum therapeutic results. Lastly, it is possible to have an external protective layer (4) which provides protection, improves stability and a long life to the dosage form, and also facilitates administration to the patient.
GR20020100442A 2002-10-14 2002-10-14 Pharmaceutical dosage form for the delivery of organic nitrates GR1004330B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GR20020100442A GR1004330B (en) 2002-10-14 2002-10-14 Pharmaceutical dosage form for the delivery of organic nitrates

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR20020100442A GR1004330B (en) 2002-10-14 2002-10-14 Pharmaceutical dosage form for the delivery of organic nitrates

Publications (1)

Publication Number Publication Date
GR1004330B true GR1004330B (en) 2003-09-05

Family

ID=29559941

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20020100442A GR1004330B (en) 2002-10-14 2002-10-14 Pharmaceutical dosage form for the delivery of organic nitrates

Country Status (1)

Country Link
GR (1) GR1004330B (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1983002056A1 (en) * 1981-12-18 1983-06-23 Key Pharma Expandable lattice of polyvinyl alcohol and polyethylene glycol
WO1999062496A1 (en) * 1998-06-03 1999-12-09 Alza Corporation Methods and devices for providing prolonged drug therapy

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1983002056A1 (en) * 1981-12-18 1983-06-23 Key Pharma Expandable lattice of polyvinyl alcohol and polyethylene glycol
WO1999062496A1 (en) * 1998-06-03 1999-12-09 Alza Corporation Methods and devices for providing prolonged drug therapy

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