GR1001366B - Extended-release opthalmic preparations. - Google Patents

Extended-release opthalmic preparations.

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Publication number
GR1001366B
GR1001366B GR920100461A GR920100461A GR1001366B GR 1001366 B GR1001366 B GR 1001366B GR 920100461 A GR920100461 A GR 920100461A GR 920100461 A GR920100461 A GR 920100461A GR 1001366 B GR1001366 B GR 1001366B
Authority
GR
Greece
Prior art keywords
extended
release
opthalmic preparations
contain
opthalmic
Prior art date
Application number
GR920100461A
Other languages
Greek (el)
Inventor
Salvatore Malandrino
Giorgio Pifferi
Roberto Seghizzi
Romano Vitali
Original Assignee
Inverni Della Beffa Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inverni Della Beffa Spa filed Critical Inverni Della Beffa Spa
Publication of GR1001366B publication Critical patent/GR1001366B/en

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Abstract

Περιγράφονται οφ?αλμικά σκευάσματα παρατεταμένης απελευ?ερώσεως τα οποία περιέχουν τις δραστικές ουσίες υπό μορφήν διαλυμάτων μεγάλου ιξώδους που σχηματίζονται από ένα μίγμα ύδατος και συμπολυμερών πολυοξυαι?υλενίου πολυοξυπροπυλενίου (πολοξαμερή) που έχουν περίπου 70% μονάδες πολυοξυαι?υλενίου και μέσο μοριακό βάρος περίπου 12,500 τα οποία χαρακτηρίζονται εκ του ότι περιέχουν ως στα?εροποιητάς μη ιονικές επιφανειακώς δραστικές ουσίες. ωSustained release ophthalmic formulations are described which contain the active substances in the form of high viscosity solutions formed from a mixture of water and polyoxyethylene polyoxypropylene copolymers (poloxamers) having about 70% polyoxyethylene units and an average molecular weight of about 12,500 which are characterized by the fact that they contain non-ionic surfactants as a steriliser. oh

GR920100461A 1992-10-16 1992-10-16 Extended-release opthalmic preparations. GR1001366B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR92100461 1992-10-16

Publications (1)

Publication Number Publication Date
GR1001366B true GR1001366B (en) 1993-10-29

Family

ID=10941213

Family Applications (1)

Application Number Title Priority Date Filing Date
GR920100461A GR1001366B (en) 1992-10-16 1992-10-16 Extended-release opthalmic preparations.

Country Status (1)

Country Link
GR (1) GR1001366B (en)

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2353295A1 (en) * 1976-05-31 1977-12-30 Kaken Chemical Co ANTIGLAUCOMATOUS OPHTHALMIC SOLUTION BASED ON A BUPRANOLOL
US4188373A (en) * 1976-02-26 1980-02-12 Cooper Laboratories, Inc. Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes
US4474751A (en) * 1983-05-16 1984-10-02 Merck & Co., Inc. Ophthalmic drug delivery system utilizing thermosetting gels
US4476140A (en) * 1983-05-16 1984-10-09 Yale University Composition and method for treatment of glaucoma
EP0253472A1 (en) * 1986-05-16 1988-01-20 Green Cross Corporation Ophthalmic flurbiprofen preparation
GB2203039A (en) * 1987-03-02 1988-10-12 American Cyanamid Co Ophthalmic local compositions containing acetazolamide
EP0317405A1 (en) * 1987-11-10 1989-05-24 Marc Plamondon Ophthalmic solution comprising iodine-polyvinylpyrrolidone complex
EP0517160A1 (en) * 1991-06-07 1992-12-09 Inverni Della Beffa S.P.A. Extended-release ophthalmic preparations

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4188373A (en) * 1976-02-26 1980-02-12 Cooper Laboratories, Inc. Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes
FR2353295A1 (en) * 1976-05-31 1977-12-30 Kaken Chemical Co ANTIGLAUCOMATOUS OPHTHALMIC SOLUTION BASED ON A BUPRANOLOL
US4474751A (en) * 1983-05-16 1984-10-02 Merck & Co., Inc. Ophthalmic drug delivery system utilizing thermosetting gels
US4476140A (en) * 1983-05-16 1984-10-09 Yale University Composition and method for treatment of glaucoma
EP0253472A1 (en) * 1986-05-16 1988-01-20 Green Cross Corporation Ophthalmic flurbiprofen preparation
GB2203039A (en) * 1987-03-02 1988-10-12 American Cyanamid Co Ophthalmic local compositions containing acetazolamide
EP0317405A1 (en) * 1987-11-10 1989-05-24 Marc Plamondon Ophthalmic solution comprising iodine-polyvinylpyrrolidone complex
EP0517160A1 (en) * 1991-06-07 1992-12-09 Inverni Della Beffa S.P.A. Extended-release ophthalmic preparations

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 110, no. 22, 29 May 1989, Columbus, Ohio, US; abstract no. 199306x, C. VERTUSCHI ET AL 'application of third derivative uv spectrophotometry to the simultaneous determination of n-methyl-5,6-benzoquinoline methyl sulfate and thonzylamine hydrochloride, in multicomponent collyrium' page 430 ;column 1 ; *

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