GEP20022658B - Method For Preparing And Purifying An N-Alkylated Aspartame Derivative - Google Patents

Method For Preparing And Purifying An N-Alkylated Aspartame Derivative

Info

Publication number
GEP20022658B
GEP20022658B GEAP19984971A GEAP1998004971A GEP20022658B GE P20022658 B GEP20022658 B GE P20022658B GE AP19984971 A GEAP19984971 A GE AP19984971A GE AP1998004971 A GEAP1998004971 A GE AP1998004971A GE P20022658 B GEP20022658 B GE P20022658B
Authority
GE
Georgia
Prior art keywords
organic solvent
purifying
preparing
solvent solution
aqueous
Prior art date
Application number
GEAP19984971A
Inventor
Prakash, (Us) Indra
Original Assignee
Nutrasweet Co Us
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nutrasweet Co Us filed Critical Nutrasweet Co Us
Publication of GEP20022658B publication Critical patent/GEP20022658B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Seasonings (AREA)

Abstract

1. Technical Result Providing high purity aspartame derivatives. 2. Essence A method for preparing and purifying the compound of the formula (1) wherein N-[N-(3,3-dimethylbutyl)-L- alpha -aspartyl]-L-phenylalanine 1-methyl ester is purified from aspartame and 3,3-dimethylbutyraldehyde by hydrogenation in an organic solvent solution followed by the formation of an aqueous/organic solvent solution having an organic solvent content of about 17% to about 30% by weight of the aqueous/organic solvent solution 3. Field of Application Chemistry.
GEAP19984971A 1998-01-29 1998-01-29 Method For Preparing And Purifying An N-Alkylated Aspartame Derivative GEP20022658B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79011398A 1998-01-29 1998-01-29

Publications (1)

Publication Number Publication Date
GEP20022658B true GEP20022658B (en) 2002-03-25

Family

ID=82607954

Family Applications (1)

Application Number Title Priority Date Filing Date
GEAP19984971A GEP20022658B (en) 1998-01-29 1998-01-29 Method For Preparing And Purifying An N-Alkylated Aspartame Derivative

Country Status (1)

Country Link
GE (1) GEP20022658B (en)

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