GEP20002100B - Modification of Endogenic Gene Expression by Regulatory Element - Google Patents

Modification of Endogenic Gene Expression by Regulatory Element

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Publication number
GEP20002100B
GEP20002100B GEAP19931159A GEAP1993001159A GEP20002100B GE P20002100 B GEP20002100 B GE P20002100B GE AP19931159 A GEAP19931159 A GE AP19931159A GE AP1993001159 A GEAP1993001159 A GE AP1993001159A GE P20002100 B GEP20002100 B GE P20002100B
Authority
GE
Georgia
Prior art keywords
gene
endogenic
construct
silent
modification
Prior art date
Application number
GEAP19931159A
Inventor
Scott Chappel
Original Assignee
Applied Res Systems Ars Holding N V Nl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Res Systems Ars Holding N V Nl filed Critical Applied Res Systems Ars Holding N V Nl
Priority to GEAP19931159A priority Critical patent/GEP20002100B/en
Publication of GEP20002100B publication Critical patent/GEP20002100B/en

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Abstract

1. Technical Result Modification of normally transcriptionally “silent” genes expression, as well as of any other endogenic gene in genome of eucariotic cell line. 2. Essence There has been elaborated: DNA construct, which defines the gene transcription induction. The construct contains a homologous chain of transcriptionally “silent” gene. It can also contain a chain of any other endogenic gene. By applying the homologous recombination said construct is inserted in the genome of eucariotic cell line so as to be operatively linked with the “silent” gene or with another endogenic gene. There are obtained eucariotic cell lines containing the construct. 3. Field of Application Biotechnology, gene engineering. Figures: 15
GEAP19931159A 1993-07-26 1993-07-26 Modification of Endogenic Gene Expression by Regulatory Element GEP20002100B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GEAP19931159A GEP20002100B (en) 1993-07-26 1993-07-26 Modification of Endogenic Gene Expression by Regulatory Element

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GEAP19931159A GEP20002100B (en) 1993-07-26 1993-07-26 Modification of Endogenic Gene Expression by Regulatory Element

Publications (1)

Publication Number Publication Date
GEP20002100B true GEP20002100B (en) 2000-05-10

Family

ID=82786960

Family Applications (1)

Application Number Title Priority Date Filing Date
GEAP19931159A GEP20002100B (en) 1993-07-26 1993-07-26 Modification of Endogenic Gene Expression by Regulatory Element

Country Status (1)

Country Link
GE (1) GEP20002100B (en)

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