GEP19981036B - Manufacturing method of aminothioazolyl derivatives of cephalosporin and of sodium and potassium salts thereof - Google Patents
Manufacturing method of aminothioazolyl derivatives of cephalosporin and of sodium and potassium salts thereofInfo
- Publication number
- GEP19981036B GEP19981036B GEAP19931224A GEAP1993001224A GEP19981036B GE P19981036 B GEP19981036 B GE P19981036B GE AP19931224 A GEAP19931224 A GE AP19931224A GE AP1993001224 A GEAP1993001224 A GE AP1993001224A GE P19981036 B GEP19981036 B GE P19981036B
- Authority
- GE
- Georgia
- Prior art keywords
- group
- cephalosporin
- derivatives
- atoms
- carbon
- Prior art date
Links
- -1 aminothioazolyl Chemical class 0.000 title abstract 4
- 229930186147 Cephalosporin Natural products 0.000 title abstract 3
- 229940124587 cephalosporin Drugs 0.000 title abstract 3
- 150000001780 cephalosporins Chemical class 0.000 title abstract 3
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 title abstract 2
- 229910052708 sodium Inorganic materials 0.000 title abstract 2
- 239000011734 sodium Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 159000000001 potassium salts Chemical class 0.000 title 1
- 125000004429 atom Chemical group 0.000 abstract 5
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 3
- 229910052799 carbon Inorganic materials 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 239000011591 potassium Substances 0.000 abstract 1
- 238000001228 spectrum Methods 0.000 abstract 1
Landscapes
- Cephalosporin Compounds (AREA)
Abstract
The invention refers to reception of aminothioazolyl derivatives of cephalosporin with the general formula: In which X designates atom of hydrogen, acetoxile group not substituted or substituted by group with С1-С6 by atoms of carbon N-piridil group, or heterocyclic thiol, in particular, 2-methylo-5,6 dioxy-1,2,5,6-tetrahydro-1,2,4-triazinthiol -3 group or its tautomer, tetrazolthiol or thiazolthiol groups, R designates methyl or adcarboxilic group with С2-С8 atoms of carbon, and R means atom of hydrogen, sodium or potassium, ammonium, silil, alkyl or alkylaril groups with С1-С20 atoms of carbon. Aminothiazolyl derivatives of cephalosporin reveal strong bactericidal action and are applied in medicine as modern antibiotics with a wide spectrum of action.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GEAP19931224A GEP19981036B (en) | 1993-07-27 | 1993-07-27 | Manufacturing method of aminothioazolyl derivatives of cephalosporin and of sodium and potassium salts thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GEAP19931224A GEP19981036B (en) | 1993-07-27 | 1993-07-27 | Manufacturing method of aminothioazolyl derivatives of cephalosporin and of sodium and potassium salts thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GEP19981036B true GEP19981036B (en) | 1998-10-27 |
Family
ID=82484209
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GEAP19931224A GEP19981036B (en) | 1993-07-27 | 1993-07-27 | Manufacturing method of aminothioazolyl derivatives of cephalosporin and of sodium and potassium salts thereof |
Country Status (1)
| Country | Link |
|---|---|
| GE (1) | GEP19981036B (en) |
-
1993
- 1993-07-27 GE GEAP19931224A patent/GEP19981036B/en unknown
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