GB9818244D0 - Macrolide compositions - Google Patents

Macrolide compositions

Info

Publication number
GB9818244D0
GB9818244D0 GBGB9818244.7A GB9818244A GB9818244D0 GB 9818244 D0 GB9818244 D0 GB 9818244D0 GB 9818244 A GB9818244 A GB 9818244A GB 9818244 D0 GB9818244 D0 GB 9818244D0
Authority
GB
United Kingdom
Prior art keywords
macrolide
macrolide compositions
compositions
stabilised
class
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GBGB9818244.7A
Other versions
GB2327610B (en
GB2327610A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9422306A external-priority patent/GB9422306D0/en
Application filed by Novartis AG filed Critical Novartis AG
Priority to GB9818244A priority Critical patent/GB2327610B/en
Priority claimed from GB9707484A external-priority patent/GB2308546B/en
Publication of GB9818244D0 publication Critical patent/GB9818244D0/en
Publication of GB2327610A publication Critical patent/GB2327610A/en
Application granted granted Critical
Publication of GB2327610B publication Critical patent/GB2327610B/en
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

A pharmaceutical composition for topical application comprising a macrolide, preferably rapamycin or a macrolide of the FK 506 class, is stabilised by the presence of an unsaturated fatty alcohol, preferably oleyl alcohol.
GB9818244A 1994-11-04 1995-10-26 Macrolide compositions Revoked GB2327610B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB9818244A GB2327610B (en) 1994-11-04 1995-10-26 Macrolide compositions

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9422306A GB9422306D0 (en) 1994-11-04 1994-11-04 Organic compounds
GB9707484A GB2308546B (en) 1994-10-26 1995-10-26 Topical macrolide compositions
GB9818244A GB2327610B (en) 1994-11-04 1995-10-26 Macrolide compositions

Publications (3)

Publication Number Publication Date
GB9818244D0 true GB9818244D0 (en) 1998-10-14
GB2327610A GB2327610A (en) 1999-02-03
GB2327610B GB2327610B (en) 1999-06-02

Family

ID=26305932

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9818244A Revoked GB2327610B (en) 1994-11-04 1995-10-26 Macrolide compositions

Country Status (1)

Country Link
GB (1) GB2327610B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0218996D0 (en) * 2002-08-14 2002-09-25 Novartis Ag Organic compounds
GB2398495B (en) * 2003-01-23 2007-08-22 Kent G Lau A drug delivery preparation comprising at least one anti-tumour drug and a topical carrier for the drug
GB0307866D0 (en) * 2003-04-04 2003-05-14 Novartis Ag Pharmaceutical composition
AU2005284422A1 (en) * 2004-09-16 2006-03-23 Bayer Healthcare Ag Dermally applicable formulations for treating skin diseases in animals

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4299826A (en) * 1979-10-12 1981-11-10 The Procter & Gamble Company Anti-acne composition
EP0474126B1 (en) * 1990-09-04 1997-03-19 Fujisawa Pharmaceutical Co., Ltd. Ointments containing tricyclic compound
DE10199039I2 (en) * 1993-10-22 2008-08-07 Hexal Ag Ind 25 PHARMACEUTICAL COMPOSITION WITH CYCLOSPORIN A, A VITAMIN DERIVATIVE AND AN EMULSIFIER

Also Published As

Publication number Publication date
GB2327610B (en) 1999-06-02
GB2327610A (en) 1999-02-03

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Legal Events

Date Code Title Description
773K Patent revoked under sect. 73(2)/1977

Free format text: PATENT REVOKED ON 20031002